Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | V87V | Silent | 2 |
| BLCA | Bladder urothelial carcinoma | D17H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D430N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E304K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E439K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K464N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q563* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | R344C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R75I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R76T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V222V | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | V438M | Missense | 1 |
| BRCA | Breast invasive carcinoma | E299Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | I544M | Missense | 1 |
| BRCA | Breast invasive carcinoma | R520C | Missense | 1 |
| BRCA | Breast invasive carcinoma | S45F | Missense | 1 |
| CESC | Cervical and endocervical cancers | S18F | Missense | 1 |
| COAD | Colon adenocarcinoma | E322D | Missense | 1 |
| COAD | Colon adenocarcinoma | G505C | Missense | 1 |
| COAD | Colon adenocarcinoma | L528P | Missense | 1 |
| COAD | Colon adenocarcinoma | R127Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R227Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R312G | Missense | 1 |
| COAD | Colon adenocarcinoma | R312R | Silent | 1 |
| COAD | Colon adenocarcinoma | R382R | Silent | 1 |
| COAD | Colon adenocarcinoma | R509C | Missense | 1 |
| ESCA | Esophageal carcinoma | G291G | Silent | 1 |
| ESCA | Esophageal carcinoma | R311L | Missense | 1 |
| ESCA | Esophageal carcinoma | R95L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A341T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D242N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | F370F | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | H238D | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | N243N | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | V438L | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | Y366C | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | K263Q | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | R6S | Missense | 1 |
| LGG | Brain Lower Grade Glioma | S276N | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | P125L | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | V108F | Missense | 1 |
| LUAD | Lung adenocarcinoma | A119A | Silent | 1 |
| LUAD | Lung adenocarcinoma | A549S | Missense | 1 |
| LUAD | Lung adenocarcinoma | A549V | Missense | 1 |
| LUAD | Lung adenocarcinoma | A589S | Missense | 1 |
| LUAD | Lung adenocarcinoma | D582H | Missense | 1 |
| LUAD | Lung adenocarcinoma | G343V | Missense | 1 |
| LUAD | Lung adenocarcinoma | H149Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | S512L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E583K | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G189D | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S56F | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | R312T | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | S178S | Silent | 1 |
| PRAD | Prostate adenocarcinoma | A425T | Missense | 1 |
| PRAD | Prostate adenocarcinoma | T548M | Missense | 1 |
| READ | Rectum adenocarcinoma | R172H | Missense | 1 |
| READ | Rectum adenocarcinoma | R41Q | Missense | 1 |
| READ | Rectum adenocarcinoma | S99A | Missense | 1 |
| SARC | Sarcoma | R509C | Missense | 1 |
| SARC | Sarcoma | T35T | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G570E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L476F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P356L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P608L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S466L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T289T | Silent | 1 |
| STAD | Stomach adenocarcinoma | G274G | Silent | 1 |
| STAD | Stomach adenocarcinoma | K503N | Missense | 1 |
| STAD | Stomach adenocarcinoma | L309I | Missense | 1 |
| STAD | Stomach adenocarcinoma | S18S | Silent | 1 |
| STAD | Stomach adenocarcinoma | S30P | Missense | 1 |
| STAD | Stomach adenocarcinoma | S64Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | T548T | Silent | 1 |
| STAD | Stomach adenocarcinoma | W390* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E232* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E281D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F181L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F370L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K426N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K464N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L434* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R271I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R400G | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R400H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R529C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S135Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T548M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V550V | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 18.8 | 12.9 | 25 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 5.7 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 1.4 | 0 |
| COAD | Colon adenocarcinoma | 367 | 12.5 | 10 | 0 |
| ESCA | Esophageal carcinoma | 185 | 6.2 | 2.9 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 12.5 | 4.3 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 2.9 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 2.9 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 1.4 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 2.9 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 6.2 | 10 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 4.3 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 1.4 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 6.2 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 2.9 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 4.3 | 0 |
| SARC | Sarcoma | 247 | 6.2 | 1.4 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 6.2 | 7.1 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 18.8 | 5.7 | 25 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 6.2 | 15.7 | 50 |