Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | A789A | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | E232K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E453E | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | E477K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | F398F | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | F694F | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | H185Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I780V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q180R | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q207Q | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | R214T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R526T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S289* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | E373Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | P641P | Silent | 1 |
| BRCA | Breast invasive carcinoma | R251Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | S785W | Missense | 1 |
| CESC | Cervical and endocervical cancers | H253N | Missense | 1 |
| CESC | Cervical and endocervical cancers | L521L | Silent | 1 |
| COAD | Colon adenocarcinoma | A513V | Missense | 1 |
| COAD | Colon adenocarcinoma | G290C | Missense | 1 |
| COAD | Colon adenocarcinoma | Q592* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | Q84R | Missense | 1 |
| COAD | Colon adenocarcinoma | S393S | Silent | 1 |
| COAD | Colon adenocarcinoma | S785S | Silent | 1 |
| COAD | Colon adenocarcinoma | V281G | Missense | 1 |
| ESCA | Esophageal carcinoma | L441L | Silent | 1 |
| ESCA | Esophageal carcinoma | Y773C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G409D | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q368Q | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R258R | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R316L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S523* | Nonsense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | L229L | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | R316Q | Missense | 1 |
| LAML | Acute Myeloid Leukemia | P641P | Silent | 1 |
| LGG | Brain Lower Grade Glioma | C618C | Silent | 1 |
| LGG | Brain Lower Grade Glioma | G367R | Missense | 1 |
| LGG | Brain Lower Grade Glioma | P641S | Missense | 1 |
| LGG | Brain Lower Grade Glioma | V252F | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | H812Y | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | T810T | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | V567E | Missense | 1 |
| LUAD | Lung adenocarcinoma | E232Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | F300C | Missense | 1 |
| LUAD | Lung adenocarcinoma | G800E | Missense | 1 |
| LUAD | Lung adenocarcinoma | R653R | Silent | 1 |
| LUAD | Lung adenocarcinoma | T610T | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | E443* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | H484D | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | P152T | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A177T | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | I804L | Missense | 1 |
| PRAD | Prostate adenocarcinoma | I199T | Missense | 1 |
| PRAD | Prostate adenocarcinoma | P471S | Missense | 1 |
| READ | Rectum adenocarcinoma | A343D | Missense | 1 |
| READ | Rectum adenocarcinoma | F264F | Silent | 1 |
| READ | Rectum adenocarcinoma | S172L | Missense | 1 |
| READ | Rectum adenocarcinoma | V400V | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L273L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L307M | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L622V | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P152P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P272P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | Q509* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | R321C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S126S | Silent | 1 |
| STAD | Stomach adenocarcinoma | I199M | Missense | 1 |
| STAD | Stomach adenocarcinoma | L497L | Silent | 1 |
| STAD | Stomach adenocarcinoma | R295R | Silent | 1 |
| STAD | Stomach adenocarcinoma | R608R | Silent | 1 |
| STAD | Stomach adenocarcinoma | R795* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | S523S | Silent | 1 |
| STAD | Stomach adenocarcinoma | W646R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C618C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E477K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F264F | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F678F | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K454R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R795* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R838C | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 16.1 | 16.3 | 14.3 |
| BRCA | Breast invasive carcinoma | 976 | 3.2 | 7 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 3.2 | 2.3 | 0 |
| COAD | Colon adenocarcinoma | 367 | 6.5 | 9.3 | 14.3 |
| ESCA | Esophageal carcinoma | 185 | 3.2 | 2.3 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 6.5 | 4.7 | 14.3 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 3.2 | 2.3 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 3.2 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 3.2 | 7 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 3.2 | 4.7 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 6.5 | 7 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 2.3 | 14.3 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 2.3 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 4.7 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 4.7 | 0 |
| READ | Rectum adenocarcinoma | 122 | 6.5 | 4.7 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 12.9 | 7 | 14.3 |
| STAD | Stomach adenocarcinoma | 393 | 12.9 | 4.7 | 14.3 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 9.7 | 7 | 14.3 |