Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| UCEC | Uterine Corpus Endometrial Carcinoma | F332L | Missense | 3 |
| BLCA | Bladder urothelial carcinoma | K9N | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | I531I | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | K414K | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | K414N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L411L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | M171I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q197* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | T166T | Silent | 1 |
| BRCA | Breast invasive carcinoma | C213C | Silent | 1 |
| BRCA | Breast invasive carcinoma | K48E | Missense | 1 |
| CESC | Cervical and endocervical cancers | D494N | Missense | 1 |
| CESC | Cervical and endocervical cancers | E413K | Missense | 1 |
| COAD | Colon adenocarcinoma | A12S | Missense | 1 |
| COAD | Colon adenocarcinoma | C62S | Missense | 1 |
| COAD | Colon adenocarcinoma | G228C | Missense | 1 |
| COAD | Colon adenocarcinoma | G77D | Missense | 1 |
| COAD | Colon adenocarcinoma | P18P | Silent | 1 |
| COAD | Colon adenocarcinoma | R288Q | Missense | 1 |
| COAD | Colon adenocarcinoma | T181T | Silent | 1 |
| ESCA | Esophageal carcinoma | D15Y | Missense | 1 |
| ESCA | Esophageal carcinoma | G423C | Missense | 1 |
| ESCA | Esophageal carcinoma | G483W | Missense | 1 |
| ESCA | Esophageal carcinoma | G544V | Missense | 1 |
| GBM | Glioblastoma multiforme | A334V | Missense | 1 |
| GBM | Glioblastoma multiforme | A431D | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | C368F | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L362L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R524W | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S26S | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | P125A | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A487T | Missense | 1 |
| LGG | Brain Lower Grade Glioma | D548E | Missense | 1 |
| LGG | Brain Lower Grade Glioma | V205I | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | D108G | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | T491T | Silent | 1 |
| LUAD | Lung adenocarcinoma | A355A | Silent | 1 |
| LUAD | Lung adenocarcinoma | D548E | Missense | 1 |
| LUAD | Lung adenocarcinoma | E320* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | Q598H | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | A355V | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | Q401H | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A164A | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | G383G | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | L477M | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R506R | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | V237M | Missense | 1 |
| PRAD | Prostate adenocarcinoma | G423G | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | E156K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P188L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P22L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P245L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S252L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S326L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Y386C | Missense | 1 |
| STAD | Stomach adenocarcinoma | D516N | Missense | 1 |
| STAD | Stomach adenocarcinoma | F449S | Missense | 1 |
| STAD | Stomach adenocarcinoma | K31K | Silent | 1 |
| STAD | Stomach adenocarcinoma | S441N | Missense | 1 |
| STAD | Stomach adenocarcinoma | T379N | Missense | 1 |
| STAD | Stomach adenocarcinoma | V298I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C169C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C213C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K104N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q389P | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R168* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R206L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R459Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T123T | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V214I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V476M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y547H | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 21.1 | 7.5 | 33.3 |
| BRCA | Breast invasive carcinoma | 976 | 5.3 | 1.9 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 3.8 | 0 |
| COAD | Colon adenocarcinoma | 367 | 10.5 | 9.4 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 7.5 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 3.8 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 10.5 | 3.8 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 1.9 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 5.7 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 5.3 | 1.9 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 5.3 | 3.8 | 33.3 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 3.8 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 15.8 | 3.8 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 5.3 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 0 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 0 | 13.2 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 5.3 | 9.4 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 15.8 | 18.9 | 33.3 |