Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| UCEC | Uterine Corpus Endometrial Carcinoma | R1020W | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | L1107F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L1123L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L146L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | Q1018E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R1020W | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R774W | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R7R | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | S993C | Missense | 1 |
| BRCA | Breast invasive carcinoma | D440N | Missense | 1 |
| BRCA | Breast invasive carcinoma | F276F | Silent | 1 |
| BRCA | Breast invasive carcinoma | G436E | Missense | 1 |
| BRCA | Breast invasive carcinoma | I535V | Missense | 1 |
| BRCA | Breast invasive carcinoma | Q355* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | R20Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | S996N | Missense | 1 |
| BRCA | Breast invasive carcinoma | T526P | Missense | 1 |
| CESC | Cervical and endocervical cancers | E136K | Missense | 1 |
| CESC | Cervical and endocervical cancers | L1099L | Silent | 1 |
| CESC | Cervical and endocervical cancers | L385F | Missense | 1 |
| CESC | Cervical and endocervical cancers | Q1159Q | Silent | 1 |
| CESC | Cervical and endocervical cancers | Q125* | Nonsense | 1 |
| CESC | Cervical and endocervical cancers | Q158Q | Silent | 1 |
| CESC | Cervical and endocervical cancers | Q355H | Missense | 1 |
| CESC | Cervical and endocervical cancers | R1068Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | S746R | Missense | 1 |
| COAD | Colon adenocarcinoma | C588C | Silent | 1 |
| COAD | Colon adenocarcinoma | F148C | Missense | 1 |
| COAD | Colon adenocarcinoma | F635F | Silent | 1 |
| COAD | Colon adenocarcinoma | H223R | Missense | 1 |
| COAD | Colon adenocarcinoma | K793N | Missense | 1 |
| COAD | Colon adenocarcinoma | K808E | Missense | 1 |
| COAD | Colon adenocarcinoma | R1045W | Missense | 1 |
| COAD | Colon adenocarcinoma | R1057C | Missense | 1 |
| COAD | Colon adenocarcinoma | R1057H | Missense | 1 |
| COAD | Colon adenocarcinoma | R1117R | Silent | 1 |
| COAD | Colon adenocarcinoma | R137Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R325R | Silent | 1 |
| COAD | Colon adenocarcinoma | R607Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R733Q | Missense | 1 |
| COAD | Colon adenocarcinoma | S960G | Missense | 1 |
| COAD | Colon adenocarcinoma | S960S | Silent | 1 |
| ESCA | Esophageal carcinoma | G371W | Missense | 1 |
| ESCA | Esophageal carcinoma | K529K | Silent | 1 |
| ESCA | Esophageal carcinoma | R431Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A285A | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | F165L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | F231F | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P235P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R9C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T1055M | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | A490V | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | S1072R | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | T802M | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | V736V | Silent | 1 |
| LGG | Brain Lower Grade Glioma | D868G | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R566W | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | C669S | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | F148L | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | I964T | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | M191L | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | N313S | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | Q820R | Missense | 1 |
| LUAD | Lung adenocarcinoma | A842V | Missense | 1 |
| LUAD | Lung adenocarcinoma | G854W | Missense | 1 |
| LUAD | Lung adenocarcinoma | L1085L | Silent | 1 |
| LUAD | Lung adenocarcinoma | L1099L | Silent | 1 |
| LUAD | Lung adenocarcinoma | L979L | Silent | 1 |
| LUAD | Lung adenocarcinoma | N879S | Missense | 1 |
| LUAD | Lung adenocarcinoma | R69R | Silent | 1 |
| LUAD | Lung adenocarcinoma | S1095C | Missense | 1 |
| LUAD | Lung adenocarcinoma | S617S | Silent | 1 |
| LUAD | Lung adenocarcinoma | Y244C | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G16C | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R339H | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R753H | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | W221L | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | D1070N | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | H223Y | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | I794L | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | R1117C | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | S960N | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | E860E | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | L549L | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | Q846Q | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | Y129C | Missense | 1 |
| PRAD | Prostate adenocarcinoma | K271K | Silent | 1 |
| PRAD | Prostate adenocarcinoma | L819M | Missense | 1 |
| PRAD | Prostate adenocarcinoma | S470Y | Missense | 1 |
| SARC | Sarcoma | L622L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | A940V | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L1149F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L72* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | L957F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P673S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R572* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | S370F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S558S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S797L | Missense | 1 |
| STAD | Stomach adenocarcinoma | A684G | Missense | 1 |
| STAD | Stomach adenocarcinoma | D1016G | Missense | 1 |
| STAD | Stomach adenocarcinoma | D889D | Silent | 1 |
| STAD | Stomach adenocarcinoma | E1098G | Missense | 1 |
| STAD | Stomach adenocarcinoma | E691* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | E859E | Silent | 1 |
| STAD | Stomach adenocarcinoma | G796G | Silent | 1 |
| STAD | Stomach adenocarcinoma | H434Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | H748R | Missense | 1 |
| STAD | Stomach adenocarcinoma | I1118V | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q894R | Missense | 1 |
| STAD | Stomach adenocarcinoma | R703L | Missense | 1 |
| STAD | Stomach adenocarcinoma | R834S | Missense | 1 |
| STAD | Stomach adenocarcinoma | R903C | Missense | 1 |
| STAD | Stomach adenocarcinoma | S750S | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | C1129Y | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | E859E | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | Q68* | Nonsense | 1 |
| THCA | Thyroid carcinoma | C207Y | Missense | 1 |
| THCA | Thyroid carcinoma | D754N | Missense | 1 |
| THCA | Thyroid carcinoma | E860E | Silent | 1 |
| THCA | Thyroid carcinoma | P536L | Missense | 1 |
| THYM | Thymoma | E860E | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A238V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D24Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F328F | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K117T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K518Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K575N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L702M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1134Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R21H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R572Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R753R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V204A | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y10H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y330Y | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 7.9 | 5.4 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 2.6 | 6.5 | 16.7 |
| CESC | Cervical and endocervical cancers | 194 | 7.9 | 5.4 | 16.7 |
| COAD | Colon adenocarcinoma | 367 | 13.2 | 11.8 | 0 |
| ESCA | Esophageal carcinoma | 185 | 2.6 | 2.2 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 7.9 | 3.2 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 2.6 | 3.2 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 2.2 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 6.5 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 13.2 | 5.4 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 4.3 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 5.4 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 7.9 | 1.1 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 2.6 | 2.2 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 0 | 0 |
| SARC | Sarcoma | 247 | 2.6 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 2.6 | 6.5 | 33.3 |
| STAD | Stomach adenocarcinoma | 393 | 10.5 | 10.8 | 16.7 |
| TGCT | Testicular Germ Cell Tumors | 147 | 2.6 | 1.1 | 16.7 |
| THCA | Thyroid carcinoma | 495 | 2.6 | 3.2 | 0 |
| THYM | Thymoma | 119 | 2.6 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 7.9 | 14 | 0 |