Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | E925K | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | S1128F | Missense | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P224P | Silent | 2 |
| BLCA | Bladder urothelial carcinoma | D244N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E428* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | E554Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E677Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E704* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | K26E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L1194I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L748L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | Q5E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q822E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S1165L | Missense | 1 |
| BRCA | Breast invasive carcinoma | E427K | Missense | 1 |
| BRCA | Breast invasive carcinoma | L1129L | Silent | 1 |
| BRCA | Breast invasive carcinoma | L1148L | Silent | 1 |
| BRCA | Breast invasive carcinoma | Q1326K | Missense | 1 |
| BRCA | Breast invasive carcinoma | Q205Q | Silent | 1 |
| BRCA | Breast invasive carcinoma | R887W | Missense | 1 |
| CESC | Cervical and endocervical cancers | E1317K | Missense | 1 |
| CESC | Cervical and endocervical cancers | E422Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | E928K | Missense | 1 |
| CESC | Cervical and endocervical cancers | L1008L | Silent | 1 |
| CESC | Cervical and endocervical cancers | L509L | Silent | 1 |
| COAD | Colon adenocarcinoma | A456A | Silent | 1 |
| COAD | Colon adenocarcinoma | C688S | Missense | 1 |
| COAD | Colon adenocarcinoma | D908N | Missense | 1 |
| COAD | Colon adenocarcinoma | I286I | Silent | 1 |
| COAD | Colon adenocarcinoma | M633V | Missense | 1 |
| COAD | Colon adenocarcinoma | P224L | Missense | 1 |
| COAD | Colon adenocarcinoma | P786R | Missense | 1 |
| COAD | Colon adenocarcinoma | R1231Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R158H | Missense | 1 |
| COAD | Colon adenocarcinoma | R66C | Missense | 1 |
| COAD | Colon adenocarcinoma | S1049I | Missense | 1 |
| COAD | Colon adenocarcinoma | S1287F | Missense | 1 |
| COAD | Colon adenocarcinoma | V97A | Missense | 1 |
| ESCA | Esophageal carcinoma | C363* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | K425E | Missense | 1 |
| ESCA | Esophageal carcinoma | Q1205L | Missense | 1 |
| ESCA | Esophageal carcinoma | R1123Q | Missense | 1 |
| ESCA | Esophageal carcinoma | R377R | Silent | 1 |
| ESCA | Esophageal carcinoma | T611M | Missense | 1 |
| GBM | Glioblastoma multiforme | A917T | Missense | 1 |
| GBM | Glioblastoma multiforme | E982K | Missense | 1 |
| GBM | Glioblastoma multiforme | R641H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | C1083S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | C295S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E861K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K903K | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L514L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L800L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | N1279S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P1050P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P15S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q205Q | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R1152Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S474F | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S975S | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | D112Y | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | E811D | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | R395R | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | S768N | Missense | 1 |
| LAML | Acute Myeloid Leukemia | E953G | Missense | 1 |
| LGG | Brain Lower Grade Glioma | E1272D | Missense | 1 |
| LGG | Brain Lower Grade Glioma | F123C | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R755Q | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | E1312G | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | E501D | Missense | 1 |
| LUAD | Lung adenocarcinoma | C630Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | E413V | Missense | 1 |
| LUAD | Lung adenocarcinoma | G442G | Silent | 1 |
| LUAD | Lung adenocarcinoma | G745C | Missense | 1 |
| LUAD | Lung adenocarcinoma | G789R | Missense | 1 |
| LUAD | Lung adenocarcinoma | I1121I | Silent | 1 |
| LUAD | Lung adenocarcinoma | K615N | Missense | 1 |
| LUAD | Lung adenocarcinoma | L831F | Missense | 1 |
| LUAD | Lung adenocarcinoma | P14L | Missense | 1 |
| LUAD | Lung adenocarcinoma | P14S | Missense | 1 |
| LUAD | Lung adenocarcinoma | R167W | Missense | 1 |
| LUAD | Lung adenocarcinoma | R614L | Missense | 1 |
| LUAD | Lung adenocarcinoma | R641L | Missense | 1 |
| LUAD | Lung adenocarcinoma | R776P | Missense | 1 |
| LUAD | Lung adenocarcinoma | S705S | Silent | 1 |
| LUAD | Lung adenocarcinoma | V374V | Silent | 1 |
| LUAD | Lung adenocarcinoma | V798M | Missense | 1 |
| LUAD | Lung adenocarcinoma | W1182R | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | A217V | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | A315A | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | D1081H | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P535L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R349R | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | V84M | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | D1224Y | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | C616Y | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | L1082M | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | M1191T | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | P1019P | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | R1147W | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R804W | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | S979N | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A900V | Missense | 1 |
| PRAD | Prostate adenocarcinoma | E980A | Missense | 1 |
| PRAD | Prostate adenocarcinoma | G516G | Silent | 1 |
| PRAD | Prostate adenocarcinoma | G745D | Missense | 1 |
| PRAD | Prostate adenocarcinoma | P902P | Silent | 1 |
| READ | Rectum adenocarcinoma | A917T | Missense | 1 |
| READ | Rectum adenocarcinoma | S820L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D244Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D290D | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | E536E | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | F307F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | F468F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G1325E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G1325R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G537S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I1215I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | I564I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L1151L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L195L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L339L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L517L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L950L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P1032S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1033P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P105L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P105P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P14P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P309S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P560L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P568S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P786P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P987L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R1152W | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R340R | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S975L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | V125V | Silent | 1 |
| STAD | Stomach adenocarcinoma | C616C | Silent | 1 |
| STAD | Stomach adenocarcinoma | D1299Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | D55G | Missense | 1 |
| STAD | Stomach adenocarcinoma | E343K | Missense | 1 |
| STAD | Stomach adenocarcinoma | G326G | Silent | 1 |
| STAD | Stomach adenocarcinoma | I1315V | Missense | 1 |
| STAD | Stomach adenocarcinoma | L517M | Missense | 1 |
| STAD | Stomach adenocarcinoma | P1197P | Silent | 1 |
| STAD | Stomach adenocarcinoma | R1124Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R641H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R804W | Missense | 1 |
| STAD | Stomach adenocarcinoma | S795S | Silent | 1 |
| STAD | Stomach adenocarcinoma | T267M | Missense | 1 |
| STAD | Stomach adenocarcinoma | V1064I | Missense | 1 |
| STAD | Stomach adenocarcinoma | V335M | Missense | 1 |
| STAD | Stomach adenocarcinoma | Y160Y | Silent | 1 |
| STAD | Stomach adenocarcinoma | Y274Y | Silent | 1 |
| THCA | Thyroid carcinoma | A315P | Missense | 1 |
| THCA | Thyroid carcinoma | T1266N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A1072T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A217T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A21T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A880A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E22* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F1314L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G1158G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K25N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K492N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L1223M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L965M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P809L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q5E | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1192W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R158H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R294* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R297I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R471K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y274Y | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 1.9 | 8.3 | 40 |
| BRCA | Breast invasive carcinoma | 976 | 5.7 | 2.5 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 3.8 | 2.5 | 0 |
| COAD | Colon adenocarcinoma | 367 | 3.8 | 9.1 | 0 |
| ESCA | Esophageal carcinoma | 185 | 1.9 | 3.3 | 20 |
| GBM | Glioblastoma multiforme | 283 | 0 | 2.5 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 11.3 | 5.8 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0.8 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 1.9 | 1.7 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0.8 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 2.5 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 1.7 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 7.5 | 11.6 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 3.8 | 3.3 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0.8 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 1.9 | 5 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 3.8 | 2.5 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 1.7 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 32.1 | 11.6 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 11.3 | 9.1 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 1.7 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 9.4 | 11.6 | 40 |