Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | D24N | Missense | 2 |
| COAD | Colon adenocarcinoma | C467C | Silent | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E169* | Nonsense | 2 |
| BLCA | Bladder urothelial carcinoma | A807A | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | D1122G | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E169K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E404* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | E40K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E40Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E66Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G126R | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I539I | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | K580E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L18F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P334A | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q1224E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q713H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S475L | Missense | 1 |
| BRCA | Breast invasive carcinoma | A478A | Silent | 1 |
| BRCA | Breast invasive carcinoma | F966F | Silent | 1 |
| BRCA | Breast invasive carcinoma | G883S | Missense | 1 |
| BRCA | Breast invasive carcinoma | I669M | Missense | 1 |
| BRCA | Breast invasive carcinoma | L760R | Missense | 1 |
| BRCA | Breast invasive carcinoma | N1036N | Silent | 1 |
| BRCA | Breast invasive carcinoma | Q1229E | Missense | 1 |
| BRCA | Breast invasive carcinoma | R358I | Missense | 1 |
| BRCA | Breast invasive carcinoma | S829N | Missense | 1 |
| CESC | Cervical and endocervical cancers | D24N | Missense | 1 |
| CESC | Cervical and endocervical cancers | E528K | Missense | 1 |
| CESC | Cervical and endocervical cancers | I1258M | Missense | 1 |
| CESC | Cervical and endocervical cancers | S1284L | Missense | 1 |
| CESC | Cervical and endocervical cancers | S882C | Missense | 1 |
| COAD | Colon adenocarcinoma | C364Y | Missense | 1 |
| COAD | Colon adenocarcinoma | E528K | Missense | 1 |
| COAD | Colon adenocarcinoma | H1249H | Silent | 1 |
| COAD | Colon adenocarcinoma | L147L | Silent | 1 |
| COAD | Colon adenocarcinoma | N224N | Silent | 1 |
| COAD | Colon adenocarcinoma | P288H | Missense | 1 |
| COAD | Colon adenocarcinoma | P876H | Missense | 1 |
| COAD | Colon adenocarcinoma | P876P | Silent | 1 |
| COAD | Colon adenocarcinoma | P876S | Missense | 1 |
| COAD | Colon adenocarcinoma | Q205R | Missense | 1 |
| COAD | Colon adenocarcinoma | R1033C | Missense | 1 |
| COAD | Colon adenocarcinoma | R262C | Missense | 1 |
| COAD | Colon adenocarcinoma | R555H | Missense | 1 |
| COAD | Colon adenocarcinoma | R85R | Silent | 1 |
| COAD | Colon adenocarcinoma | R950C | Missense | 1 |
| COAD | Colon adenocarcinoma | V1299A | Missense | 1 |
| ESCA | Esophageal carcinoma | G1171G | Silent | 1 |
| ESCA | Esophageal carcinoma | P1072H | Missense | 1 |
| ESCA | Esophageal carcinoma | R262H | Missense | 1 |
| ESCA | Esophageal carcinoma | S766S | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D398N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | F758L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | N267S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P677P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V1131V | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | A1103T | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | H867Q | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | I850S | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | K381R | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | V11V | Silent | 1 |
| LGG | Brain Lower Grade Glioma | A749V | Missense | 1 |
| LGG | Brain Lower Grade Glioma | K580R | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R569H | Missense | 1 |
| LGG | Brain Lower Grade Glioma | V1308F | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | K425R | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | N755S | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | P780S | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | T868T | Silent | 1 |
| LUAD | Lung adenocarcinoma | G269E | Missense | 1 |
| LUAD | Lung adenocarcinoma | G783V | Missense | 1 |
| LUAD | Lung adenocarcinoma | I150V | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q1229* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | R1093W | Missense | 1 |
| LUAD | Lung adenocarcinoma | R402T | Missense | 1 |
| LUAD | Lung adenocarcinoma | W706R | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | A743A | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | E1001* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | L1311L | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | L238Q | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | Q374Q | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | P876P | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | S1155Y | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | S447L | Missense | 1 |
| PRAD | Prostate adenocarcinoma | D596G | Missense | 1 |
| PRAD | Prostate adenocarcinoma | H715Y | Missense | 1 |
| PRAD | Prostate adenocarcinoma | T1182T | Silent | 1 |
| PRAD | Prostate adenocarcinoma | T818A | Missense | 1 |
| READ | Rectum adenocarcinoma | A478S | Missense | 1 |
| READ | Rectum adenocarcinoma | C467C | Silent | 1 |
| SARC | Sarcoma | P407L | Missense | 1 |
| SARC | Sarcoma | P407S | Missense | 1 |
| SARC | Sarcoma | S347F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A478V | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D563N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G1026* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | K562K | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R132R | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S445F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S913F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | V1007A | Missense | 1 |
| STAD | Stomach adenocarcinoma | A1103A | Silent | 1 |
| STAD | Stomach adenocarcinoma | A1126T | Missense | 1 |
| STAD | Stomach adenocarcinoma | A23A | Silent | 1 |
| STAD | Stomach adenocarcinoma | C64Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | C687C | Silent | 1 |
| STAD | Stomach adenocarcinoma | E98G | Missense | 1 |
| STAD | Stomach adenocarcinoma | F530F | Silent | 1 |
| STAD | Stomach adenocarcinoma | F567V | Missense | 1 |
| STAD | Stomach adenocarcinoma | H245H | Silent | 1 |
| STAD | Stomach adenocarcinoma | K767T | Missense | 1 |
| STAD | Stomach adenocarcinoma | N671D | Missense | 1 |
| STAD | Stomach adenocarcinoma | P1170A | Missense | 1 |
| STAD | Stomach adenocarcinoma | P764S | Missense | 1 |
| STAD | Stomach adenocarcinoma | R107* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | R1162* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | R550H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R653Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | S445P | Missense | 1 |
| STAD | Stomach adenocarcinoma | S935G | Missense | 1 |
| STAD | Stomach adenocarcinoma | V38V | Silent | 1 |
| STAD | Stomach adenocarcinoma | V531I | Missense | 1 |
| STAD | Stomach adenocarcinoma | W1048* | Nonsense | 1 |
| TGCT | Testicular Germ Cell Tumors | C1009F | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | P820P | Silent | 1 |
| THCA | Thyroid carcinoma | I747V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | H983P | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I845L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K122N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1221C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R480* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R75I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R886R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R926R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T319I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V243F | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V658V | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 5.6 | 14.7 | 10 |
| BRCA | Breast invasive carcinoma | 976 | 8.3 | 6.3 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 5.3 | 0 |
| COAD | Colon adenocarcinoma | 367 | 19.4 | 11.6 | 0 |
| ESCA | Esophageal carcinoma | 185 | 5.6 | 2.1 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 5.6 | 3.2 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 1.1 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 2.8 | 3.2 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 4.2 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 2.8 | 3.2 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 0 | 6.3 | 10 |
| LUSC | Lung squamous cell carcinoma | 177 | 8.3 | 1.1 | 10 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 2.8 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 2.1 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 2.8 | 3.2 | 0 |
| READ | Rectum adenocarcinoma | 122 | 2.8 | 1.1 | 0 |
| SARC | Sarcoma | 247 | 0 | 3.2 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 5.6 | 5.3 | 10 |
| STAD | Stomach adenocarcinoma | 393 | 16.7 | 13.7 | 30 |
| TGCT | Testicular Germ Cell Tumors | 147 | 2.8 | 1.1 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 1.1 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 8.3 | 7.4 | 30 |