Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| UCEC | Uterine Corpus Endometrial Carcinoma | R1025C | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | A482P | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D551H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E1032K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E1034K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E466Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | F185F | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | F832F | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L194L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L952L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | P68A | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q700Q | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | S457C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Y726F | Missense | 1 |
| BRCA | Breast invasive carcinoma | E426K | Missense | 1 |
| BRCA | Breast invasive carcinoma | E426Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | E728Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | K1012R | Missense | 1 |
| BRCA | Breast invasive carcinoma | L499F | Missense | 1 |
| BRCA | Breast invasive carcinoma | N128S | Missense | 1 |
| BRCA | Breast invasive carcinoma | P348L | Missense | 1 |
| BRCA | Breast invasive carcinoma | T428T | Silent | 1 |
| BRCA | Breast invasive carcinoma | T440P | Missense | 1 |
| BRCA | Breast invasive carcinoma | V462V | Silent | 1 |
| CESC | Cervical and endocervical cancers | S936Y | Missense | 1 |
| COAD | Colon adenocarcinoma | A2T | Missense | 1 |
| COAD | Colon adenocarcinoma | A567T | Missense | 1 |
| COAD | Colon adenocarcinoma | E118K | Missense | 1 |
| COAD | Colon adenocarcinoma | I1029I | Silent | 1 |
| COAD | Colon adenocarcinoma | N911N | Silent | 1 |
| COAD | Colon adenocarcinoma | R119Q | Missense | 1 |
| COAD | Colon adenocarcinoma | T926T | Silent | 1 |
| COAD | Colon adenocarcinoma | V321A | Missense | 1 |
| COAD | Colon adenocarcinoma | W53G | Missense | 1 |
| ESCA | Esophageal carcinoma | A485T | Missense | 1 |
| ESCA | Esophageal carcinoma | A568T | Missense | 1 |
| ESCA | Esophageal carcinoma | K602N | Missense | 1 |
| ESCA | Esophageal carcinoma | R438M | Missense | 1 |
| ESCA | Esophageal carcinoma | S508L | Missense | 1 |
| ESCA | Esophageal carcinoma | T243T | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E1028K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E465K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G683* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R154I | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R966T | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | F202F | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | Q645H | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | E372Q | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | I156N | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A101D | Missense | 1 |
| LGG | Brain Lower Grade Glioma | I297T | Missense | 1 |
| LGG | Brain Lower Grade Glioma | M584T | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | Y1053* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | H857L | Missense | 1 |
| LUAD | Lung adenocarcinoma | K314N | Missense | 1 |
| LUAD | Lung adenocarcinoma | P174T | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q846E | Missense | 1 |
| LUAD | Lung adenocarcinoma | S459S | Silent | 1 |
| LUAD | Lung adenocarcinoma | T539M | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E118* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | E558Q | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | I87V | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | T428M | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | E944A | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R605H | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R921M | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R744W | Missense | 1 |
| PRAD | Prostate adenocarcinoma | S936F | Missense | 1 |
| READ | Rectum adenocarcinoma | G265G | Silent | 1 |
| READ | Rectum adenocarcinoma | R1013I | Missense | 1 |
| READ | Rectum adenocarcinoma | R110C | Missense | 1 |
| READ | Rectum adenocarcinoma | V48V | Silent | 1 |
| SARC | Sarcoma | N290S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F585L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F585V | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P416L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P416P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S184F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S593S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | T167A | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | V500V | Silent | 1 |
| STAD | Stomach adenocarcinoma | K756N | Missense | 1 |
| STAD | Stomach adenocarcinoma | L222L | Silent | 1 |
| STAD | Stomach adenocarcinoma | L771P | Missense | 1 |
| STAD | Stomach adenocarcinoma | L941F | Missense | 1 |
| STAD | Stomach adenocarcinoma | R152W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R498H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R605H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R825C | Missense | 1 |
| STAD | Stomach adenocarcinoma | S36F | Missense | 1 |
| STAD | Stomach adenocarcinoma | S713L | Missense | 1 |
| STAD | Stomach adenocarcinoma | T76M | Missense | 1 |
| STAD | Stomach adenocarcinoma | V490M | Missense | 1 |
| STAD | Stomach adenocarcinoma | V544M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A1061V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R400Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R597H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R647Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R825H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S28N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S713L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V319M | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 26.3 | 9.9 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 10.5 | 9.9 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 1.2 | 0 |
| COAD | Colon adenocarcinoma | 367 | 15.8 | 7.4 | 0 |
| ESCA | Esophageal carcinoma | 185 | 5.3 | 6.2 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 4.9 | 33.3 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 5.3 | 1.2 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 2.5 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 3.7 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 0 | 33.3 |
| LUAD | Lung adenocarcinoma | 533 | 5.3 | 6.2 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 2.5 | 33.3 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 1.2 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 3.7 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 2.5 | 0 |
| READ | Rectum adenocarcinoma | 122 | 10.5 | 2.5 | 0 |
| SARC | Sarcoma | 247 | 0 | 1.2 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 15.8 | 6.2 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 5.3 | 14.8 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 0 | 12.3 | 0 |