Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | E784E | Silent | 3 |
| LGG | Brain Lower Grade Glioma | A591A | Silent | 2 |
| BLCA | Bladder urothelial carcinoma | E631Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E849E | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | F269F | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | H42N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K306T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L650L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | Q1049Q | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | Q1053H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R1020T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R898T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S405L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V412V | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | V817I | Missense | 1 |
| BRCA | Breast invasive carcinoma | A630S | Missense | 1 |
| BRCA | Breast invasive carcinoma | E28E | Silent | 1 |
| BRCA | Breast invasive carcinoma | G146G | Silent | 1 |
| BRCA | Breast invasive carcinoma | I480K | Missense | 1 |
| BRCA | Breast invasive carcinoma | P230P | Silent | 1 |
| BRCA | Breast invasive carcinoma | Q226E | Missense | 1 |
| BRCA | Breast invasive carcinoma | R121H | Missense | 1 |
| BRCA | Breast invasive carcinoma | R863* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | S451L | Missense | 1 |
| CESC | Cervical and endocervical cancers | A630V | Missense | 1 |
| CESC | Cervical and endocervical cancers | I825I | Silent | 1 |
| CESC | Cervical and endocervical cancers | K1031K | Silent | 1 |
| CESC | Cervical and endocervical cancers | S1047C | Missense | 1 |
| CESC | Cervical and endocervical cancers | V296V | Silent | 1 |
| COAD | Colon adenocarcinoma | D396N | Missense | 1 |
| COAD | Colon adenocarcinoma | I464I | Silent | 1 |
| COAD | Colon adenocarcinoma | K125N | Missense | 1 |
| COAD | Colon adenocarcinoma | P383H | Missense | 1 |
| COAD | Colon adenocarcinoma | P52L | Missense | 1 |
| COAD | Colon adenocarcinoma | R220* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | R572H | Missense | 1 |
| COAD | Colon adenocarcinoma | S880S | Silent | 1 |
| COAD | Colon adenocarcinoma | T768M | Missense | 1 |
| COAD | Colon adenocarcinoma | V870M | Missense | 1 |
| ESCA | Esophageal carcinoma | C14F | Missense | 1 |
| ESCA | Esophageal carcinoma | E504K | Missense | 1 |
| ESCA | Esophageal carcinoma | E708V | Missense | 1 |
| ESCA | Esophageal carcinoma | P12S | Missense | 1 |
| ESCA | Esophageal carcinoma | P52H | Missense | 1 |
| ESCA | Esophageal carcinoma | T623R | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A103T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D594Y | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E387D | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | H278L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K53M | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S506L | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | K720K | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | R745Q | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R724W | Missense | 1 |
| LGG | Brain Lower Grade Glioma | Y61* | Nonsense | 1 |
| LIHC | Liver hepatocellular carcinoma | C813D | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | G45G | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | P348L | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | V1039A | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | V547L | Missense | 1 |
| LUAD | Lung adenocarcinoma | A136A | Silent | 1 |
| LUAD | Lung adenocarcinoma | A376S | Missense | 1 |
| LUAD | Lung adenocarcinoma | A781A | Silent | 1 |
| LUAD | Lung adenocarcinoma | E430E | Silent | 1 |
| LUAD | Lung adenocarcinoma | E519D | Missense | 1 |
| LUAD | Lung adenocarcinoma | G538G | Silent | 1 |
| LUAD | Lung adenocarcinoma | H644H | Silent | 1 |
| LUAD | Lung adenocarcinoma | I544I | Silent | 1 |
| LUAD | Lung adenocarcinoma | K381I | Missense | 1 |
| LUAD | Lung adenocarcinoma | K499N | Missense | 1 |
| LUAD | Lung adenocarcinoma | L765F | Missense | 1 |
| LUAD | Lung adenocarcinoma | P791L | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q589L | Missense | 1 |
| LUAD | Lung adenocarcinoma | R100S | Missense | 1 |
| LUAD | Lung adenocarcinoma | V251V | Silent | 1 |
| LUAD | Lung adenocarcinoma | V782L | Missense | 1 |
| LUAD | Lung adenocarcinoma | Y1040* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | Y953C | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | A646S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E695* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | G1018G | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | S434F | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | V420V | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | E784D | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | S678S | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | A591V | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | C778C | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | M319V | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R1041H | Missense | 1 |
| READ | Rectum adenocarcinoma | R220Q | Missense | 1 |
| READ | Rectum adenocarcinoma | T677A | Missense | 1 |
| SARC | Sarcoma | C931F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E390* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | E792K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L33F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S250L | Missense | 1 |
| STAD | Stomach adenocarcinoma | A1036A | Silent | 1 |
| STAD | Stomach adenocarcinoma | A103S | Missense | 1 |
| STAD | Stomach adenocarcinoma | A750A | Silent | 1 |
| STAD | Stomach adenocarcinoma | C718R | Missense | 1 |
| STAD | Stomach adenocarcinoma | D408E | Missense | 1 |
| STAD | Stomach adenocarcinoma | D852G | Missense | 1 |
| STAD | Stomach adenocarcinoma | E981V | Missense | 1 |
| STAD | Stomach adenocarcinoma | G106S | Missense | 1 |
| STAD | Stomach adenocarcinoma | I73V | Missense | 1 |
| STAD | Stomach adenocarcinoma | N11D | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1020* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | R121H | Missense | 1 |
| STAD | Stomach adenocarcinoma | T921I | Missense | 1 |
| STAD | Stomach adenocarcinoma | V723V | Silent | 1 |
| STAD | Stomach adenocarcinoma | W751C | Missense | 1 |
| STAD | Stomach adenocarcinoma | Y255Y | Silent | 1 |
| STAD | Stomach adenocarcinoma | Y474Y | Silent | 1 |
| THCA | Thyroid carcinoma | G302E | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A1036A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A614V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A719G | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A750V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A781A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C60C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E268K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E498D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I926I | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I962T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q804Q | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R121H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R58I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R786* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S534R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S713R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T379I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T623M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T623T | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T887T | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V158I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V440V | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 11.4 | 9.2 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 6.8 | 5.7 | 12.5 |
| CESC | Cervical and endocervical cancers | 194 | 6.8 | 2.3 | 0 |
| COAD | Colon adenocarcinoma | 367 | 11.4 | 8 | 12.5 |
| ESCA | Esophageal carcinoma | 185 | 0 | 6.9 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 6.9 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 2.3 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 1.1 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 4.5 | 1.1 | 12.5 |
| LIHC | Liver hepatocellular carcinoma | 373 | 2.3 | 4.6 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 15.9 | 11.5 | 12.5 |
| LUSC | Lung squamous cell carcinoma | 177 | 4.5 | 2.3 | 12.5 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 2.3 | 1.1 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 2.3 | 3.4 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 2.3 | 0 |
| SARC | Sarcoma | 247 | 0 | 1.1 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 0 | 3.4 | 12.5 |
| STAD | Stomach adenocarcinoma | 393 | 11.4 | 12.6 | 12.5 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 1.1 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 18.2 | 14.9 | 12.5 |