Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| UCEC | Uterine Corpus Endometrial Carcinoma | R893Q | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | E1139K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E131Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E516K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E906* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | E944K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | F480L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I1165V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I48M | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I492M | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K1422N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L1233F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L432V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q799* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | R1584K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R52W | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R785R | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | S1194* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | S1319F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S528C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V133V | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | V268V | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | V830V | Silent | 1 |
| BRCA | Breast invasive carcinoma | D257H | Missense | 1 |
| BRCA | Breast invasive carcinoma | E939Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | G245G | Silent | 1 |
| BRCA | Breast invasive carcinoma | L117M | Missense | 1 |
| BRCA | Breast invasive carcinoma | L1681P | Missense | 1 |
| BRCA | Breast invasive carcinoma | P1474P | Silent | 1 |
| BRCA | Breast invasive carcinoma | R264Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | R674W | Missense | 1 |
| BRCA | Breast invasive carcinoma | S1366S | Silent | 1 |
| CESC | Cervical and endocervical cancers | D1500H | Missense | 1 |
| CESC | Cervical and endocervical cancers | E1095K | Missense | 1 |
| CESC | Cervical and endocervical cancers | F1316F | Silent | 1 |
| CESC | Cervical and endocervical cancers | H319D | Missense | 1 |
| CESC | Cervical and endocervical cancers | L1074L | Silent | 1 |
| CESC | Cervical and endocervical cancers | L149V | Missense | 1 |
| CESC | Cervical and endocervical cancers | P331T | Missense | 1 |
| CESC | Cervical and endocervical cancers | R1282H | Missense | 1 |
| CESC | Cervical and endocervical cancers | R266Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | R782* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | A1648A | Silent | 1 |
| COAD | Colon adenocarcinoma | E111E | Silent | 1 |
| COAD | Colon adenocarcinoma | E1207* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | E1384K | Missense | 1 |
| COAD | Colon adenocarcinoma | E1649V | Missense | 1 |
| COAD | Colon adenocarcinoma | E190D | Missense | 1 |
| COAD | Colon adenocarcinoma | F566I | Missense | 1 |
| COAD | Colon adenocarcinoma | K1504K | Silent | 1 |
| COAD | Colon adenocarcinoma | K1535M | Missense | 1 |
| COAD | Colon adenocarcinoma | L1229P | Missense | 1 |
| COAD | Colon adenocarcinoma | M1390I | Missense | 1 |
| COAD | Colon adenocarcinoma | P1237L | Missense | 1 |
| COAD | Colon adenocarcinoma | R603Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R648Q | Missense | 1 |
| COAD | Colon adenocarcinoma | S1201P | Missense | 1 |
| COAD | Colon adenocarcinoma | S231N | Missense | 1 |
| COAD | Colon adenocarcinoma | V1093A | Missense | 1 |
| COAD | Colon adenocarcinoma | V1328M | Missense | 1 |
| COAD | Colon adenocarcinoma | W1256R | Missense | 1 |
| ESCA | Esophageal carcinoma | E1114K | Missense | 1 |
| ESCA | Esophageal carcinoma | L1455M | Missense | 1 |
| ESCA | Esophageal carcinoma | M634I | Missense | 1 |
| ESCA | Esophageal carcinoma | R1467W | Missense | 1 |
| ESCA | Esophageal carcinoma | R764* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | T1078T | Silent | 1 |
| GBM | Glioblastoma multiforme | L1191F | Missense | 1 |
| GBM | Glioblastoma multiforme | L1540* | Nonsense | 1 |
| GBM | Glioblastoma multiforme | R1222R | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E305K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E651E | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E980D | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K960K | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L166L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | M277V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P1371S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S400S | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T1225I | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | D1339V | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | F526F | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | V537I | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | C1615R | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | P1420R | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A274T | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A522A | Silent | 1 |
| LGG | Brain Lower Grade Glioma | D1339D | Silent | 1 |
| LGG | Brain Lower Grade Glioma | G1086D | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R428W | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | I492M | Missense | 1 |
| LUAD | Lung adenocarcinoma | A1052T | Missense | 1 |
| LUAD | Lung adenocarcinoma | A11P | Missense | 1 |
| LUAD | Lung adenocarcinoma | A510S | Missense | 1 |
| LUAD | Lung adenocarcinoma | D1106V | Missense | 1 |
| LUAD | Lung adenocarcinoma | D1460D | Silent | 1 |
| LUAD | Lung adenocarcinoma | I1296M | Missense | 1 |
| LUAD | Lung adenocarcinoma | K1567N | Missense | 1 |
| LUAD | Lung adenocarcinoma | L105V | Missense | 1 |
| LUAD | Lung adenocarcinoma | M876I | Missense | 1 |
| LUAD | Lung adenocarcinoma | P325S | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q1411* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | R1077R | Silent | 1 |
| LUAD | Lung adenocarcinoma | R1090R | Silent | 1 |
| LUAD | Lung adenocarcinoma | R735S | Missense | 1 |
| LUAD | Lung adenocarcinoma | S1603C | Missense | 1 |
| LUAD | Lung adenocarcinoma | V921V | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | A1611A | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | E64Q | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | L157V | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | L166L | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | L925L | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | P1241S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R264* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | R359L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S1403F | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | T134T | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | Y553C | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | L1229F | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | L1448F | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | Q655E | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | E18Q | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | L725F | Missense | 1 |
| PCPG | Pheochromocytoma and Paraganglioma | D273D | Silent | 1 |
| PRAD | Prostate adenocarcinoma | A274T | Missense | 1 |
| PRAD | Prostate adenocarcinoma | G1172V | Missense | 1 |
| PRAD | Prostate adenocarcinoma | K1206* | Nonsense | 1 |
| PRAD | Prostate adenocarcinoma | Q1197P | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R1239W | Missense | 1 |
| PRAD | Prostate adenocarcinoma | V1426V | Silent | 1 |
| READ | Rectum adenocarcinoma | D1079N | Missense | 1 |
| READ | Rectum adenocarcinoma | D1633G | Missense | 1 |
| READ | Rectum adenocarcinoma | D486N | Missense | 1 |
| READ | Rectum adenocarcinoma | E825* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | K238T | Missense | 1 |
| READ | Rectum adenocarcinoma | M634I | Missense | 1 |
| READ | Rectum adenocarcinoma | R1239W | Missense | 1 |
| READ | Rectum adenocarcinoma | S1404Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A1150A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | D772A | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E343K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I114I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L1211F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L763V | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | M1683V | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1237P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P1420L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1592L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1592P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P325L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P624L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P710P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R1428Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R719C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1201F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S414C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S414S | Silent | 1 |
| STAD | Stomach adenocarcinoma | A1253V | Missense | 1 |
| STAD | Stomach adenocarcinoma | D905D | Silent | 1 |
| STAD | Stomach adenocarcinoma | E825* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | E855V | Missense | 1 |
| STAD | Stomach adenocarcinoma | I539V | Missense | 1 |
| STAD | Stomach adenocarcinoma | K374R | Missense | 1 |
| STAD | Stomach adenocarcinoma | K713N | Missense | 1 |
| STAD | Stomach adenocarcinoma | L1300F | Missense | 1 |
| STAD | Stomach adenocarcinoma | L725L | Silent | 1 |
| STAD | Stomach adenocarcinoma | L894L | Silent | 1 |
| STAD | Stomach adenocarcinoma | P1041L | Missense | 1 |
| STAD | Stomach adenocarcinoma | P17P | Silent | 1 |
| STAD | Stomach adenocarcinoma | P449L | Missense | 1 |
| STAD | Stomach adenocarcinoma | P469Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1051Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1261W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R301W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R607C | Missense | 1 |
| STAD | Stomach adenocarcinoma | R696W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R968R | Silent | 1 |
| STAD | Stomach adenocarcinoma | S1187S | Silent | 1 |
| STAD | Stomach adenocarcinoma | V230L | Missense | 1 |
| STAD | Stomach adenocarcinoma | W1053* | Nonsense | 1 |
| TGCT | Testicular Germ Cell Tumors | P423S | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | V669I | Missense | 1 |
| THCA | Thyroid carcinoma | K1162Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A1006T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A351V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A941T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C683C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D1079N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D628G | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E638* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G284D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I492S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K113N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K1407N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K982N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L888F | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P215P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P328P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P423L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P721T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q597P | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1031C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1508Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R266* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R674R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R696W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R782Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R818R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S1423N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S1488I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T793T | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 8.2 | 10.2 | 20 |
| BRCA | Breast invasive carcinoma | 976 | 6.1 | 4.1 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 4.1 | 4.8 | 6.7 |
| COAD | Colon adenocarcinoma | 367 | 6.1 | 10.2 | 6.7 |
| ESCA | Esophageal carcinoma | 185 | 2 | 2.7 | 6.7 |
| GBM | Glioblastoma multiforme | 283 | 2 | 0.7 | 6.7 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 8.2 | 3.4 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 2 | 1.4 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 1.4 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 4.1 | 2 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 0.7 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 8.2 | 7.5 | 6.7 |
| LUSC | Lung squamous cell carcinoma | 177 | 8.2 | 4.1 | 6.7 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 2 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 1.4 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 2 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 2 | 2.7 | 6.7 |
| READ | Rectum adenocarcinoma | 122 | 0 | 4.8 | 6.7 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 12.2 | 8.8 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 12.2 | 10.2 | 13.3 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 1.4 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0.7 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 12.2 | 15 | 13.3 |