Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | E221E | Silent | 2 |
| COAD | Colon adenocarcinoma | R179C | Missense | 2 |
| COAD | Colon adenocarcinoma | S1222P | Missense | 2 |
| COAD | Colon adenocarcinoma | S1222S | Silent | 2 |
| COAD | Colon adenocarcinoma | S643P | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | D111N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K650N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L756I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P464P | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | R1451R | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | S1298C | Missense | 1 |
| BRCA | Breast invasive carcinoma | A1000A | Silent | 1 |
| BRCA | Breast invasive carcinoma | A1295P | Missense | 1 |
| BRCA | Breast invasive carcinoma | A663V | Missense | 1 |
| BRCA | Breast invasive carcinoma | D1107H | Missense | 1 |
| BRCA | Breast invasive carcinoma | E1274K | Missense | 1 |
| BRCA | Breast invasive carcinoma | E981K | Missense | 1 |
| BRCA | Breast invasive carcinoma | E985E | Silent | 1 |
| BRCA | Breast invasive carcinoma | K459N | Missense | 1 |
| BRCA | Breast invasive carcinoma | L115L | Silent | 1 |
| BRCA | Breast invasive carcinoma | Q1294L | Missense | 1 |
| BRCA | Breast invasive carcinoma | V161V | Silent | 1 |
| CESC | Cervical and endocervical cancers | A32A | Silent | 1 |
| CESC | Cervical and endocervical cancers | E1283K | Missense | 1 |
| CESC | Cervical and endocervical cancers | E1490K | Missense | 1 |
| CESC | Cervical and endocervical cancers | I31I | Silent | 1 |
| CESC | Cervical and endocervical cancers | I689I | Silent | 1 |
| CESC | Cervical and endocervical cancers | S717* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | C1188S | Missense | 1 |
| COAD | Colon adenocarcinoma | D254Y | Missense | 1 |
| COAD | Colon adenocarcinoma | E1527K | Missense | 1 |
| COAD | Colon adenocarcinoma | E465D | Missense | 1 |
| COAD | Colon adenocarcinoma | E926G | Missense | 1 |
| COAD | Colon adenocarcinoma | E933A | Missense | 1 |
| COAD | Colon adenocarcinoma | P1253T | Missense | 1 |
| COAD | Colon adenocarcinoma | P554H | Missense | 1 |
| COAD | Colon adenocarcinoma | P573P | Silent | 1 |
| COAD | Colon adenocarcinoma | R1059R | Silent | 1 |
| COAD | Colon adenocarcinoma | R1166H | Missense | 1 |
| COAD | Colon adenocarcinoma | R179H | Missense | 1 |
| COAD | Colon adenocarcinoma | R681* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | V581M | Missense | 1 |
| COAD | Colon adenocarcinoma | W1420* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | W534R | Missense | 1 |
| COAD | Colon adenocarcinoma | W983* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | S1178L | Missense | 1 |
| ESCA | Esophageal carcinoma | S204S | Silent | 1 |
| GBM | Glioblastoma multiforme | R1165C | Missense | 1 |
| GBM | Glioblastoma multiforme | R627C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D337N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E1024* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G1354E | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K1092K | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | M670I | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R211P | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V504L | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | C512W | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | C730F | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | C730R | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E1152K | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E284* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E592V | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E798* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | G536W | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | H733P | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | K459* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | Q1554H | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | Q813* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | R1458W | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | R215* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | R681* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | S1110* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | V119V | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | G1339D | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A652T | Missense | 1 |
| LGG | Brain Lower Grade Glioma | G398G | Silent | 1 |
| LGG | Brain Lower Grade Glioma | K498M | Missense | 1 |
| LGG | Brain Lower Grade Glioma | P480L | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R929Q | Missense | 1 |
| LGG | Brain Lower Grade Glioma | S1541F | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | E693G | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | E906G | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | G170V | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | L1351L | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | M673V | Missense | 1 |
| LUAD | Lung adenocarcinoma | A1009A | Silent | 1 |
| LUAD | Lung adenocarcinoma | A1489T | Missense | 1 |
| LUAD | Lung adenocarcinoma | A882A | Silent | 1 |
| LUAD | Lung adenocarcinoma | D347D | Silent | 1 |
| LUAD | Lung adenocarcinoma | E1405E | Silent | 1 |
| LUAD | Lung adenocarcinoma | E656K | Missense | 1 |
| LUAD | Lung adenocarcinoma | E784* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | E985* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | G170* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | H300D | Missense | 1 |
| LUAD | Lung adenocarcinoma | L1220L | Silent | 1 |
| LUAD | Lung adenocarcinoma | L1549L | Silent | 1 |
| LUAD | Lung adenocarcinoma | L257V | Missense | 1 |
| LUAD | Lung adenocarcinoma | L662L | Silent | 1 |
| LUAD | Lung adenocarcinoma | L700L | Silent | 1 |
| LUAD | Lung adenocarcinoma | L763L | Silent | 1 |
| LUAD | Lung adenocarcinoma | M251I | Missense | 1 |
| LUAD | Lung adenocarcinoma | M506I | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q675* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | R1483W | Missense | 1 |
| LUAD | Lung adenocarcinoma | R328L | Missense | 1 |
| LUAD | Lung adenocarcinoma | R585H | Missense | 1 |
| LUAD | Lung adenocarcinoma | Y535C | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | A614S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E386Q | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E646V | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | L756I | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | Q168L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R68R | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | E23Q | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | G912E | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | L1547L | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | P1429L | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | R179H | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | S643F | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | Q237H | Missense | 1 |
| PCPG | Pheochromocytoma and Paraganglioma | N587D | Missense | 1 |
| READ | Rectum adenocarcinoma | E645* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | S1222P | Missense | 1 |
| SARC | Sarcoma | E1152D | Missense | 1 |
| SARC | Sarcoma | N491S | Missense | 1 |
| SARC | Sarcoma | P1539S | Missense | 1 |
| SARC | Sarcoma | R212Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A1149A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | A1264A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | H350Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I238I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L1455L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P231L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P454S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R1218C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1537L | Missense | 1 |
| STAD | Stomach adenocarcinoma | A319A | Silent | 1 |
| STAD | Stomach adenocarcinoma | A401A | Silent | 1 |
| STAD | Stomach adenocarcinoma | A406A | Silent | 1 |
| STAD | Stomach adenocarcinoma | A612A | Silent | 1 |
| STAD | Stomach adenocarcinoma | C1551Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | C825C | Silent | 1 |
| STAD | Stomach adenocarcinoma | D754D | Silent | 1 |
| STAD | Stomach adenocarcinoma | E1476K | Missense | 1 |
| STAD | Stomach adenocarcinoma | E1497Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | E669D | Missense | 1 |
| STAD | Stomach adenocarcinoma | F1089F | Silent | 1 |
| STAD | Stomach adenocarcinoma | F806L | Missense | 1 |
| STAD | Stomach adenocarcinoma | H632Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | M950V | Missense | 1 |
| STAD | Stomach adenocarcinoma | P163S | Missense | 1 |
| STAD | Stomach adenocarcinoma | P480Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R136Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R159H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R211W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R378R | Silent | 1 |
| STAD | Stomach adenocarcinoma | R634H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R787Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | S287S | Silent | 1 |
| STAD | Stomach adenocarcinoma | V81A | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | C825C | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | S1485* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A1106T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A1292T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A22T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C368C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D703D | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E386Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F92L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G1053D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G333G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G591R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I1419V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L1026F | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N230N | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N574D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P1231T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1435H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R766W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R936C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S1182S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S1484N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T713M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V1214M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y157Y | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 3.9 | 3.3 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 7.8 | 5.7 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 5.9 | 1.6 | 5.6 |
| COAD | Colon adenocarcinoma | 367 | 11.8 | 14.8 | 16.7 |
| ESCA | Esophageal carcinoma | 185 | 2 | 0.8 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 1.6 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 2 | 4.1 | 5.6 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 2 | 7.4 | 38.9 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0.8 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 2 | 4.1 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 2 | 3.3 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 17.6 | 8.2 | 22.2 |
| LUSC | Lung squamous cell carcinoma | 177 | 2 | 4.1 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 2 | 4.1 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0.8 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0.8 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 0.8 | 5.6 |
| SARC | Sarcoma | 247 | 0 | 3.3 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 7.8 | 4.1 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 17.6 | 12.3 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 2 | 0 | 5.6 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 11.8 | 13.9 | 0 |