Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | D693N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E745K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K640N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K701K | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L1525* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | S282L | Missense | 1 |
| COAD | Colon adenocarcinoma | A460A | Silent | 1 |
| COAD | Colon adenocarcinoma | L1003L | Silent | 1 |
| COAD | Colon adenocarcinoma | P1164P | Silent | 1 |
| COAD | Colon adenocarcinoma | Q1301Q | Silent | 1 |
| COAD | Colon adenocarcinoma | Q578Q | Silent | 1 |
| COAD | Colon adenocarcinoma | R1419C | Missense | 1 |
| COAD | Colon adenocarcinoma | R1442Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R768* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | S114N | Missense | 1 |
| GBM | Glioblastoma multiforme | S307C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A1304A | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D1129V | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E126K | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | G1390V | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | E971D | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | K186E | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | L290L | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | R1056R | Silent | 1 |
| LUAD | Lung adenocarcinoma | A1018P | Missense | 1 |
| LUAD | Lung adenocarcinoma | E455K | Missense | 1 |
| LUAD | Lung adenocarcinoma | L344L | Silent | 1 |
| LUAD | Lung adenocarcinoma | L898L | Silent | 1 |
| LUAD | Lung adenocarcinoma | R1069I | Missense | 1 |
| LUAD | Lung adenocarcinoma | V1288V | Silent | 1 |
| LUAD | Lung adenocarcinoma | W503L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E1348* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | E184* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | R1433R | Silent | 1 |
| PRAD | Prostate adenocarcinoma | A926T | Missense | 1 |
| PRAD | Prostate adenocarcinoma | M1388I | Missense | 1 |
| PRAD | Prostate adenocarcinoma | V489V | Silent | 1 |
| READ | Rectum adenocarcinoma | L1077I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P588S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R132C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R1478* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | R624G | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1356F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S949F | Missense | 1 |
| STAD | Stomach adenocarcinoma | C358W | Missense | 1 |
| STAD | Stomach adenocarcinoma | D1287E | Missense | 1 |
| STAD | Stomach adenocarcinoma | P15P | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | A610D | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 6.7 | 14.3 | 20 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 0 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 0 | 0 |
| COAD | Colon adenocarcinoma | 367 | 33.3 | 10.7 | 20 |
| ESCA | Esophageal carcinoma | 185 | 0 | 0 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 3.6 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 6.7 | 3.6 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 7.1 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 13.3 | 7.1 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 20 | 14.3 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 6.7 | 0 | 40 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 6.7 | 7.1 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 3.6 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 0 | 17.9 | 20 |
| STAD | Stomach adenocarcinoma | 393 | 6.7 | 7.1 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 3.6 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 0 | 0 | 0 |