Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | S215L | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | S838F | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | D1632G | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I698I | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L649L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | P747A | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S864C | Missense | 1 |
| BRCA | Breast invasive carcinoma | E1346K | Missense | 1 |
| BRCA | Breast invasive carcinoma | L1103L | Silent | 1 |
| BRCA | Breast invasive carcinoma | P300L | Missense | 1 |
| CESC | Cervical and endocervical cancers | L804L | Silent | 1 |
| CESC | Cervical and endocervical cancers | R1556L | Missense | 1 |
| CESC | Cervical and endocervical cancers | R328W | Missense | 1 |
| COAD | Colon adenocarcinoma | A1557T | Missense | 1 |
| COAD | Colon adenocarcinoma | A25V | Missense | 1 |
| COAD | Colon adenocarcinoma | E1620* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | G718G | Silent | 1 |
| COAD | Colon adenocarcinoma | P1082L | Missense | 1 |
| COAD | Colon adenocarcinoma | P54H | Missense | 1 |
| COAD | Colon adenocarcinoma | R38H | Missense | 1 |
| COAD | Colon adenocarcinoma | R478H | Missense | 1 |
| COAD | Colon adenocarcinoma | R984W | Missense | 1 |
| COAD | Colon adenocarcinoma | T1434M | Missense | 1 |
| COAD | Colon adenocarcinoma | V1243M | Missense | 1 |
| COAD | Colon adenocarcinoma | V1508I | Missense | 1 |
| ESCA | Esophageal carcinoma | P1318Q | Missense | 1 |
| ESCA | Esophageal carcinoma | R1075Q | Missense | 1 |
| ESCA | Esophageal carcinoma | R306W | Missense | 1 |
| ESCA | Esophageal carcinoma | R84T | Missense | 1 |
| ESCA | Esophageal carcinoma | T761A | Missense | 1 |
| GBM | Glioblastoma multiforme | P1050L | Missense | 1 |
| GBM | Glioblastoma multiforme | P849L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E1122D | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E881K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G830R | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L804L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P1065P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R669* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R908C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S402S | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S852L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V1166V | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V1462V | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | G1360C | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | L1181P | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | L1218M | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | A1423A | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | A18A | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | W1410C | Missense | 1 |
| LGG | Brain Lower Grade Glioma | G885G | Silent | 1 |
| LGG | Brain Lower Grade Glioma | L1201P | Missense | 1 |
| LGG | Brain Lower Grade Glioma | P1100H | Missense | 1 |
| LGG | Brain Lower Grade Glioma | P250A | Missense | 1 |
| LGG | Brain Lower Grade Glioma | S552N | Missense | 1 |
| LGG | Brain Lower Grade Glioma | V1200A | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | F1396F | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | R192W | Missense | 1 |
| LUAD | Lung adenocarcinoma | A58D | Missense | 1 |
| LUAD | Lung adenocarcinoma | D1254G | Missense | 1 |
| LUAD | Lung adenocarcinoma | E1026E | Silent | 1 |
| LUAD | Lung adenocarcinoma | E1174Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | E1591K | Missense | 1 |
| LUAD | Lung adenocarcinoma | E961K | Missense | 1 |
| LUAD | Lung adenocarcinoma | G137A | Missense | 1 |
| LUAD | Lung adenocarcinoma | G189V | Missense | 1 |
| LUAD | Lung adenocarcinoma | G296C | Missense | 1 |
| LUAD | Lung adenocarcinoma | K1169N | Missense | 1 |
| LUAD | Lung adenocarcinoma | L1103L | Silent | 1 |
| LUAD | Lung adenocarcinoma | R411W | Missense | 1 |
| LUAD | Lung adenocarcinoma | S30P | Missense | 1 |
| LUAD | Lung adenocarcinoma | S705C | Missense | 1 |
| LUAD | Lung adenocarcinoma | V1166V | Silent | 1 |
| LUAD | Lung adenocarcinoma | V535M | Missense | 1 |
| LUAD | Lung adenocarcinoma | V994V | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | E926K | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G647G | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | L732V | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P217L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P470A | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R229Q | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S399T | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A1281T | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | D1037N | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | G659R | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | G813E | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | S399T | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | S444I | Missense | 1 |
| PCPG | Pheochromocytoma and Paraganglioma | G859S | Missense | 1 |
| PCPG | Pheochromocytoma and Paraganglioma | Q1550E | Missense | 1 |
| PRAD | Prostate adenocarcinoma | D1569D | Silent | 1 |
| PRAD | Prostate adenocarcinoma | I1215F | Missense | 1 |
| PRAD | Prostate adenocarcinoma | P7L | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R1035L | Missense | 1 |
| READ | Rectum adenocarcinoma | P104P | Silent | 1 |
| SARC | Sarcoma | R1031C | Missense | 1 |
| SARC | Sarcoma | R437C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A377V | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F140F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G661E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G88E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H615Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I1440V | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L101L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L1222L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P335S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P35P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P428P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P440S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P588L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P588S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R102W | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R1156* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | R1457Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R880R | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S1221S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S1287S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S388F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S806F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S866S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S867L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T923T | Silent | 1 |
| STAD | Stomach adenocarcinoma | A1051A | Silent | 1 |
| STAD | Stomach adenocarcinoma | A1572A | Silent | 1 |
| STAD | Stomach adenocarcinoma | A422V | Missense | 1 |
| STAD | Stomach adenocarcinoma | A429A | Silent | 1 |
| STAD | Stomach adenocarcinoma | A857T | Missense | 1 |
| STAD | Stomach adenocarcinoma | C382C | Silent | 1 |
| STAD | Stomach adenocarcinoma | D359D | Silent | 1 |
| STAD | Stomach adenocarcinoma | E1240K | Missense | 1 |
| STAD | Stomach adenocarcinoma | G1098G | Silent | 1 |
| STAD | Stomach adenocarcinoma | G1113S | Missense | 1 |
| STAD | Stomach adenocarcinoma | G718G | Silent | 1 |
| STAD | Stomach adenocarcinoma | L113L | Silent | 1 |
| STAD | Stomach adenocarcinoma | P658P | Silent | 1 |
| STAD | Stomach adenocarcinoma | R102W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1093C | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1194W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1263W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R14W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1566S | Missense | 1 |
| STAD | Stomach adenocarcinoma | R306Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | S39S | Silent | 1 |
| STAD | Stomach adenocarcinoma | T127I | Missense | 1 |
| STAD | Stomach adenocarcinoma | T398S | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | L732L | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | Q1614H | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | Q722P | Missense | 1 |
| THCA | Thyroid carcinoma | A884V | Missense | 1 |
| THCA | Thyroid carcinoma | S399T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A1352V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D1333E | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E1577K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G1565G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G326G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L461L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P32P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P415P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P529P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1246H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V1462M | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 4.2 | 4.5 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 2.1 | 1.8 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 2.1 | 1.8 | 0 |
| COAD | Colon adenocarcinoma | 367 | 2.1 | 9 | 33.3 |
| ESCA | Esophageal carcinoma | 185 | 0 | 4.5 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 1.8 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 10.4 | 4.5 | 33.3 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 2.7 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 4.2 | 0.9 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 2.1 | 4.5 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 2.1 | 0.9 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 8.3 | 11.7 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 2.1 | 5.4 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 5.4 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 1.8 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 2.1 | 2.7 | 0 |
| READ | Rectum adenocarcinoma | 122 | 2.1 | 0 | 0 |
| SARC | Sarcoma | 247 | 0 | 1.8 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 20.8 | 14.4 | 33.3 |
| STAD | Stomach adenocarcinoma | 393 | 20.8 | 11.7 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 2.1 | 1.8 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 1.8 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 12.5 | 4.5 | 0 |