Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | R874Q | Missense | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R874Q | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | E18K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E392Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E569K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E703K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | F384L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | H1732Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | H1814Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I546V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K137K | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | K226T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L698L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | P1014R | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P1720A | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q1367E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q177H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q507Q | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | Q566Q | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | R572R | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | S1079* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | S1303* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | S1425F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S1563C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S1651F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S410F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | T1088I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | T1514P | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V686V | Silent | 1 |
| BRCA | Breast invasive carcinoma | H43P | Missense | 1 |
| BRCA | Breast invasive carcinoma | L1107L | Silent | 1 |
| BRCA | Breast invasive carcinoma | N87S | Missense | 1 |
| BRCA | Breast invasive carcinoma | Q1843K | Missense | 1 |
| BRCA | Breast invasive carcinoma | R1100* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | R1493Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | S1405L | Missense | 1 |
| BRCA | Breast invasive carcinoma | S1724S | Silent | 1 |
| BRCA | Breast invasive carcinoma | S218* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | S23* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | V395F | Missense | 1 |
| BRCA | Breast invasive carcinoma | V537I | Missense | 1 |
| BRCA | Breast invasive carcinoma | Y1531C | Missense | 1 |
| CESC | Cervical and endocervical cancers | H1744Y | Missense | 1 |
| CESC | Cervical and endocervical cancers | P1696A | Missense | 1 |
| CESC | Cervical and endocervical cancers | Q1588E | Missense | 1 |
| CESC | Cervical and endocervical cancers | Q1648* | Nonsense | 1 |
| CESC | Cervical and endocervical cancers | Q1745E | Missense | 1 |
| COAD | Colon adenocarcinoma | A415T | Missense | 1 |
| COAD | Colon adenocarcinoma | C138F | Missense | 1 |
| COAD | Colon adenocarcinoma | D1278H | Missense | 1 |
| COAD | Colon adenocarcinoma | D320N | Missense | 1 |
| COAD | Colon adenocarcinoma | D902N | Missense | 1 |
| COAD | Colon adenocarcinoma | E420D | Missense | 1 |
| COAD | Colon adenocarcinoma | G1198D | Missense | 1 |
| COAD | Colon adenocarcinoma | G1835G | Silent | 1 |
| COAD | Colon adenocarcinoma | H1420H | Silent | 1 |
| COAD | Colon adenocarcinoma | K1154N | Missense | 1 |
| COAD | Colon adenocarcinoma | L1107L | Silent | 1 |
| COAD | Colon adenocarcinoma | L1428P | Missense | 1 |
| COAD | Colon adenocarcinoma | L45L | Silent | 1 |
| COAD | Colon adenocarcinoma | P1042H | Missense | 1 |
| COAD | Colon adenocarcinoma | R1165I | Missense | 1 |
| COAD | Colon adenocarcinoma | R1167C | Missense | 1 |
| COAD | Colon adenocarcinoma | R405Q | Missense | 1 |
| COAD | Colon adenocarcinoma | S1471* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | S1471S | Silent | 1 |
| COAD | Colon adenocarcinoma | T912T | Silent | 1 |
| COAD | Colon adenocarcinoma | V1421I | Missense | 1 |
| COAD | Colon adenocarcinoma | V28I | Missense | 1 |
| ESCA | Esophageal carcinoma | E800K | Missense | 1 |
| ESCA | Esophageal carcinoma | H1675R | Missense | 1 |
| ESCA | Esophageal carcinoma | I106V | Missense | 1 |
| ESCA | Esophageal carcinoma | K788M | Missense | 1 |
| ESCA | Esophageal carcinoma | P1720L | Missense | 1 |
| ESCA | Esophageal carcinoma | Q367* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | Q507K | Missense | 1 |
| ESCA | Esophageal carcinoma | S1301C | Missense | 1 |
| GBM | Glioblastoma multiforme | P6L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A304S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A304V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G1601G | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | H1744Y | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K344K | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P1360S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q1367E | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q1620E | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q505K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R1135Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R69C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S1412* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S53L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S773C | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | C1199R | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E1398D | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | H1669R | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | Q1588R | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | D1086V | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | E299D | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | I262S | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | L720R | Missense | 1 |
| LGG | Brain Lower Grade Glioma | P1450P | Silent | 1 |
| LGG | Brain Lower Grade Glioma | P1717Q | Missense | 1 |
| LGG | Brain Lower Grade Glioma | P1773P | Silent | 1 |
| LGG | Brain Lower Grade Glioma | Q663Q | Silent | 1 |
| LGG | Brain Lower Grade Glioma | T443I | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | A21V | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | D1197A | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | D618H | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | E634E | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | F1750L | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | I481T | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | N1346S | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | N324N | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | Q840* | Nonsense | 1 |
| LIHC | Liver hepatocellular carcinoma | S1612A | Missense | 1 |
| LUAD | Lung adenocarcinoma | D1127G | Missense | 1 |
| LUAD | Lung adenocarcinoma | E603Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | E737Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | E949Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | F654F | Silent | 1 |
| LUAD | Lung adenocarcinoma | K347N | Missense | 1 |
| LUAD | Lung adenocarcinoma | L1181L | Silent | 1 |
| LUAD | Lung adenocarcinoma | N1614K | Missense | 1 |
| LUAD | Lung adenocarcinoma | N325S | Missense | 1 |
| LUAD | Lung adenocarcinoma | P6P | Silent | 1 |
| LUAD | Lung adenocarcinoma | Q1251Q | Silent | 1 |
| LUAD | Lung adenocarcinoma | R405L | Missense | 1 |
| LUAD | Lung adenocarcinoma | S909C | Missense | 1 |
| LUAD | Lung adenocarcinoma | T699K | Missense | 1 |
| LUAD | Lung adenocarcinoma | V33A | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | A1503V | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | D1028H | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E634E | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | P1549S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S1577F | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | G980R | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | M906L | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | S1228C | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | S1471T | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | Y931C | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A1508T | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A632S | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | S1021L | Missense | 1 |
| PRAD | Prostate adenocarcinoma | G1313G | Silent | 1 |
| PRAD | Prostate adenocarcinoma | H1660N | Missense | 1 |
| PRAD | Prostate adenocarcinoma | K722T | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R963H | Missense | 1 |
| PRAD | Prostate adenocarcinoma | S1752L | Missense | 1 |
| PRAD | Prostate adenocarcinoma | V1258L | Missense | 1 |
| READ | Rectum adenocarcinoma | A1200A | Silent | 1 |
| READ | Rectum adenocarcinoma | E1016* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | E921* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | K338N | Missense | 1 |
| READ | Rectum adenocarcinoma | R1100Q | Missense | 1 |
| READ | Rectum adenocarcinoma | R1276Q | Missense | 1 |
| READ | Rectum adenocarcinoma | R834I | Missense | 1 |
| READ | Rectum adenocarcinoma | S952Y | Missense | 1 |
| SARC | Sarcoma | E989K | Missense | 1 |
| SARC | Sarcoma | R178R | Silent | 1 |
| SARC | Sarcoma | R179R | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | A1513T | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F588F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P1417S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1719S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1748P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P95L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R1085K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1082S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S265L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S952F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T1136T | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | T443I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | V220V | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | Y431* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | A12T | Missense | 1 |
| STAD | Stomach adenocarcinoma | A1508T | Missense | 1 |
| STAD | Stomach adenocarcinoma | A1624V | Missense | 1 |
| STAD | Stomach adenocarcinoma | A608T | Missense | 1 |
| STAD | Stomach adenocarcinoma | A76T | Missense | 1 |
| STAD | Stomach adenocarcinoma | D1143N | Missense | 1 |
| STAD | Stomach adenocarcinoma | H153Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | K552T | Missense | 1 |
| STAD | Stomach adenocarcinoma | N828H | Missense | 1 |
| STAD | Stomach adenocarcinoma | P1627P | Silent | 1 |
| STAD | Stomach adenocarcinoma | P6Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q663R | Missense | 1 |
| STAD | Stomach adenocarcinoma | R246C | Missense | 1 |
| STAD | Stomach adenocarcinoma | R915W | Missense | 1 |
| STAD | Stomach adenocarcinoma | S1612F | Missense | 1 |
| STAD | Stomach adenocarcinoma | S1666S | Silent | 1 |
| STAD | Stomach adenocarcinoma | S1735P | Missense | 1 |
| STAD | Stomach adenocarcinoma | S655C | Missense | 1 |
| STAD | Stomach adenocarcinoma | T1455M | Missense | 1 |
| STAD | Stomach adenocarcinoma | T912T | Silent | 1 |
| STAD | Stomach adenocarcinoma | V1604L | Missense | 1 |
| STAD | Stomach adenocarcinoma | V223A | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | P894P | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | Y66C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A1842V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C616R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D1143N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D225A | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D902N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E1388K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E599* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E806* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E921D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E994* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F374L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I1142I | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I951I | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L1027L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L1321R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L1590V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L307L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N324H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P1644P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q1836H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q337H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1100* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R473H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S909F | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S952Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T1455T | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y895* | Nonsense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 13.3 | 11.6 | 11.1 |
| BRCA | Breast invasive carcinoma | 976 | 4.4 | 4.9 | 16.7 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 2.4 | 5.6 |
| COAD | Colon adenocarcinoma | 367 | 13.3 | 10.4 | 5.6 |
| ESCA | Esophageal carcinoma | 185 | 0 | 4.3 | 5.6 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0.6 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 4.4 | 6.7 | 5.6 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 2.4 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 2.4 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 6.7 | 1.2 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 4.4 | 4.3 | 5.6 |
| LUAD | Lung adenocarcinoma | 533 | 8.9 | 6.7 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 2.2 | 2.4 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 3 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 1.8 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 2.2 | 3 | 0 |
| READ | Rectum adenocarcinoma | 122 | 2.2 | 3 | 11.1 |
| SARC | Sarcoma | 247 | 4.4 | 0.6 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 11.1 | 4.9 | 5.6 |
| STAD | Stomach adenocarcinoma | 393 | 6.7 | 11.6 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 2.2 | 0.6 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 13.3 | 11 | 27.8 |