Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | D222N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D22D | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | E677Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E697* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | E8K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I279I | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | K646K | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | R34R | Silent | 1 |
| BRCA | Breast invasive carcinoma | D464H | Missense | 1 |
| BRCA | Breast invasive carcinoma | L185L | Silent | 1 |
| BRCA | Breast invasive carcinoma | L440L | Silent | 1 |
| BRCA | Breast invasive carcinoma | Q491H | Missense | 1 |
| BRCA | Breast invasive carcinoma | R59W | Missense | 1 |
| BRCA | Breast invasive carcinoma | T557M | Missense | 1 |
| BRCA | Breast invasive carcinoma | V674V | Silent | 1 |
| CESC | Cervical and endocervical cancers | E57K | Missense | 1 |
| CESC | Cervical and endocervical cancers | S304F | Missense | 1 |
| CESC | Cervical and endocervical cancers | S481S | Silent | 1 |
| COAD | Colon adenocarcinoma | A483T | Missense | 1 |
| COAD | Colon adenocarcinoma | A522T | Missense | 1 |
| COAD | Colon adenocarcinoma | D363D | Silent | 1 |
| COAD | Colon adenocarcinoma | D705N | Missense | 1 |
| COAD | Colon adenocarcinoma | G425G | Silent | 1 |
| COAD | Colon adenocarcinoma | G644R | Missense | 1 |
| COAD | Colon adenocarcinoma | L24P | Missense | 1 |
| COAD | Colon adenocarcinoma | L72F | Missense | 1 |
| COAD | Colon adenocarcinoma | R382Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R673C | Missense | 1 |
| COAD | Colon adenocarcinoma | T347T | Silent | 1 |
| ESCA | Esophageal carcinoma | E19* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | V545V | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E424Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | F198F | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K620K | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K646K | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L566L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P194S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V681L | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | K186R | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | K492R | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | Y247C | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A410V | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R328W | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R352H | Missense | 1 |
| LGG | Brain Lower Grade Glioma | V450I | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | L245H | Missense | 1 |
| LUAD | Lung adenocarcinoma | K107N | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q237L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E17* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | L185M | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | E20K | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | G29D | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | L24L | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | I495T | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | K107K | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | L442M | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | P634P | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | R328R | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | Y357N | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R284L | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R328W | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R673C | Missense | 1 |
| READ | Rectum adenocarcinoma | P634L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A436V | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E100K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H400H | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | K123R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L454F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L454L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P439S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R284Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | W510L | Missense | 1 |
| STAD | Stomach adenocarcinoma | D364D | Silent | 1 |
| STAD | Stomach adenocarcinoma | K405N | Missense | 1 |
| STAD | Stomach adenocarcinoma | K686E | Missense | 1 |
| STAD | Stomach adenocarcinoma | R242Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R394* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | R639* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | R639Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | T98I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A687T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C583C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D180N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D23N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L440M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | M16K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P499P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R394Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R419* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R632I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S189I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S662L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T638T | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V210V | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 14.8 | 4.9 | 16.7 |
| BRCA | Breast invasive carcinoma | 976 | 11.1 | 6.6 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 3.7 | 3.3 | 0 |
| COAD | Colon adenocarcinoma | 367 | 11.1 | 13.1 | 0 |
| ESCA | Esophageal carcinoma | 185 | 3.7 | 0 | 16.7 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 14.8 | 4.9 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 1.6 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 3.3 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 6.6 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 1.6 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 0 | 3.3 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 1.6 | 16.7 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 3.7 | 3.3 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 11.1 | 4.9 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 4.9 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 1.6 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 7.4 | 11.5 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 3.7 | 8.2 | 33.3 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 14.8 | 14.8 | 16.7 |