Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| ESCA | Esophageal carcinoma | K336T | Missense | 2 |
| HNSC | Head and Neck squamous cell carcinoma | Q193* | Nonsense | 2 |
| BLCA | Bladder urothelial carcinoma | C237C | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | E91Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K9K | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L257V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S41R | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V64V | Silent | 1 |
| BRCA | Breast invasive carcinoma | A66A | Silent | 1 |
| BRCA | Breast invasive carcinoma | D158H | Missense | 1 |
| BRCA | Breast invasive carcinoma | H349P | Missense | 1 |
| BRCA | Breast invasive carcinoma | L411L | Silent | 1 |
| BRCA | Breast invasive carcinoma | R522K | Missense | 1 |
| BRCA | Breast invasive carcinoma | V328V | Silent | 1 |
| CESC | Cervical and endocervical cancers | D238N | Missense | 1 |
| COAD | Colon adenocarcinoma | A107A | Silent | 1 |
| COAD | Colon adenocarcinoma | A497A | Silent | 1 |
| COAD | Colon adenocarcinoma | A51V | Missense | 1 |
| COAD | Colon adenocarcinoma | D135G | Missense | 1 |
| COAD | Colon adenocarcinoma | F160C | Missense | 1 |
| COAD | Colon adenocarcinoma | F575V | Missense | 1 |
| COAD | Colon adenocarcinoma | G332S | Missense | 1 |
| COAD | Colon adenocarcinoma | G557S | Missense | 1 |
| COAD | Colon adenocarcinoma | G618D | Missense | 1 |
| COAD | Colon adenocarcinoma | Q26H | Missense | 1 |
| COAD | Colon adenocarcinoma | R221C | Missense | 1 |
| COAD | Colon adenocarcinoma | R420C | Missense | 1 |
| COAD | Colon adenocarcinoma | V552V | Silent | 1 |
| ESCA | Esophageal carcinoma | F330C | Missense | 1 |
| ESCA | Esophageal carcinoma | N268I | Missense | 1 |
| ESCA | Esophageal carcinoma | N5N | Silent | 1 |
| ESCA | Esophageal carcinoma | P360S | Missense | 1 |
| ESCA | Esophageal carcinoma | S436* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | T38N | Missense | 1 |
| ESCA | Esophageal carcinoma | V283G | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A282T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D21D | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E69D | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | H606Y | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P187R | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q49H | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | P264R | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | R23H | Missense | 1 |
| LGG | Brain Lower Grade Glioma | Q172K | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | G386E | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S99S | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | W141* | Nonsense | 1 |
| LIHC | Liver hepatocellular carcinoma | W56C | Missense | 1 |
| LUAD | Lung adenocarcinoma | A168A | Silent | 1 |
| LUAD | Lung adenocarcinoma | E28* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | E451K | Missense | 1 |
| LUAD | Lung adenocarcinoma | G392C | Missense | 1 |
| LUAD | Lung adenocarcinoma | K159I | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q539K | Missense | 1 |
| LUAD | Lung adenocarcinoma | S183T | Missense | 1 |
| LUAD | Lung adenocarcinoma | T581T | Silent | 1 |
| LUAD | Lung adenocarcinoma | W128L | Missense | 1 |
| LUAD | Lung adenocarcinoma | W162L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E252* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | K176N | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R536W | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | T581R | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | V494V | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | I468F | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | L529F | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R516Q | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | V201M | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | W56* | Nonsense | 1 |
| PRAD | Prostate adenocarcinoma | A594V | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R17C | Missense | 1 |
| READ | Rectum adenocarcinoma | A212V | Missense | 1 |
| READ | Rectum adenocarcinoma | L58V | Missense | 1 |
| READ | Rectum adenocarcinoma | T367T | Silent | 1 |
| SARC | Sarcoma | D21D | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | D126N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D13N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D220N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D320N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D419N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E143K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E613K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F446F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G140R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G386R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I151I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | I601I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | K413K | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | M12I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | M300I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | M88I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P152S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P519S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P530S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P593L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P67P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P95P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R203R | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R516Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R536W | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S407L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S41N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | V68F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | W128* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | A285V | Missense | 1 |
| STAD | Stomach adenocarcinoma | D323E | Missense | 1 |
| STAD | Stomach adenocarcinoma | G489S | Missense | 1 |
| STAD | Stomach adenocarcinoma | L208S | Missense | 1 |
| STAD | Stomach adenocarcinoma | P98S | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q539Q | Silent | 1 |
| STAD | Stomach adenocarcinoma | S189Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | S554P | Missense | 1 |
| STAD | Stomach adenocarcinoma | T509M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A212T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A212V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D234N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E60* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K157T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K464Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R17H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R542C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V64V | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 11.5 | 3.4 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 11.5 | 3.4 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 1.1 | 0 |
| COAD | Colon adenocarcinoma | 367 | 11.5 | 11.4 | 0 |
| ESCA | Esophageal carcinoma | 185 | 3.8 | 8 | 11.1 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 3.8 | 5.7 | 22.2 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 2.3 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 1.1 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 3.8 | 2.3 | 11.1 |
| LUAD | Lung adenocarcinoma | 533 | 7.7 | 8 | 11.1 |
| LUSC | Lung squamous cell carcinoma | 177 | 3.8 | 3.4 | 11.1 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 1.1 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 3.4 | 11.1 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 2.3 | 0 |
| READ | Rectum adenocarcinoma | 122 | 3.8 | 2.3 | 0 |
| SARC | Sarcoma | 247 | 3.8 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 26.9 | 23.9 | 11.1 |
| STAD | Stomach adenocarcinoma | 393 | 3.8 | 9.1 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 3.8 | 8 | 11.1 |