Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | E179* | Nonsense | 2 |
| PAAD | Pancreatic adenocarcinoma | A7V | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | A414T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | F571L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I180T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L435F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R377Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R609C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S99F | Missense | 1 |
| BRCA | Breast invasive carcinoma | A504T | Missense | 1 |
| BRCA | Breast invasive carcinoma | E252D | Missense | 1 |
| BRCA | Breast invasive carcinoma | G371D | Missense | 1 |
| BRCA | Breast invasive carcinoma | R377Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | S97A | Missense | 1 |
| BRCA | Breast invasive carcinoma | Y300Y | Silent | 1 |
| CESC | Cervical and endocervical cancers | I202I | Silent | 1 |
| CESC | Cervical and endocervical cancers | L327V | Missense | 1 |
| CESC | Cervical and endocervical cancers | R544C | Missense | 1 |
| COAD | Colon adenocarcinoma | F259L | Missense | 1 |
| COAD | Colon adenocarcinoma | K186T | Missense | 1 |
| COAD | Colon adenocarcinoma | L429L | Silent | 1 |
| COAD | Colon adenocarcinoma | L429P | Missense | 1 |
| COAD | Colon adenocarcinoma | M420I | Missense | 1 |
| COAD | Colon adenocarcinoma | R372C | Missense | 1 |
| COAD | Colon adenocarcinoma | R544H | Missense | 1 |
| COAD | Colon adenocarcinoma | T443T | Silent | 1 |
| COAD | Colon adenocarcinoma | V317I | Missense | 1 |
| COAD | Colon adenocarcinoma | V365V | Silent | 1 |
| ESCA | Esophageal carcinoma | N52S | Missense | 1 |
| ESCA | Esophageal carcinoma | R512R | Silent | 1 |
| GBM | Glioblastoma multiforme | S425N | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | R377R | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | F381L | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | H320Q | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | R544C | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R609C | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | A109S | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | G316C | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | N480Y | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | V25V | Silent | 1 |
| LUAD | Lung adenocarcinoma | A440A | Silent | 1 |
| LUAD | Lung adenocarcinoma | A7V | Missense | 1 |
| LUAD | Lung adenocarcinoma | G65D | Missense | 1 |
| LUAD | Lung adenocarcinoma | L535L | Silent | 1 |
| LUAD | Lung adenocarcinoma | M403V | Missense | 1 |
| LUAD | Lung adenocarcinoma | R74* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | V432L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | D412Y | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | F153F | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | H320Y | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P391P | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | L429L | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | R586C | Missense | 1 |
| PCPG | Pheochromocytoma and Paraganglioma | A7V | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A414T | Missense | 1 |
| PRAD | Prostate adenocarcinoma | D143G | Missense | 1 |
| PRAD | Prostate adenocarcinoma | I614V | Missense | 1 |
| READ | Rectum adenocarcinoma | Y595H | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E24K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P515S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P612S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R586C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S59F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S73S | Silent | 1 |
| STAD | Stomach adenocarcinoma | A598V | Missense | 1 |
| STAD | Stomach adenocarcinoma | D367D | Silent | 1 |
| STAD | Stomach adenocarcinoma | F470L | Missense | 1 |
| STAD | Stomach adenocarcinoma | G310R | Missense | 1 |
| STAD | Stomach adenocarcinoma | H582R | Missense | 1 |
| STAD | Stomach adenocarcinoma | K519E | Missense | 1 |
| STAD | Stomach adenocarcinoma | R377Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R413C | Missense | 1 |
| STAD | Stomach adenocarcinoma | R413R | Silent | 1 |
| STAD | Stomach adenocarcinoma | R583Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | T443M | Missense | 1 |
| STAD | Stomach adenocarcinoma | V499A | Missense | 1 |
| STAD | Stomach adenocarcinoma | W265* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | W484* | Nonsense | 1 |
| TGCT | Testicular Germ Cell Tumors | A555D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A414T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A557V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E48A | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G392R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N242I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P119P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P90S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R79Q | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 10.4 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 5.9 | 7.5 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 5.9 | 3 | 0 |
| COAD | Colon adenocarcinoma | 367 | 17.6 | 10.4 | 40 |
| ESCA | Esophageal carcinoma | 185 | 5.9 | 1.5 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 1.5 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 0 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 5.9 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 4.5 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 1.5 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 5.9 | 4.5 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 11.8 | 6 | 20 |
| LUSC | Lung squamous cell carcinoma | 177 | 11.8 | 3 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 5.9 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 4.5 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 1.5 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 4.5 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 1.5 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 5.9 | 7.5 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 11.8 | 14.9 | 40 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 1.5 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 5.9 | 10.4 | 0 |