Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| UCEC | Uterine Corpus Endometrial Carcinoma | R22C | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | C344S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | C377R | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D121N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E508K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E545Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E549Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E562K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G67D | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V530I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | W509* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | C357C | Silent | 1 |
| BRCA | Breast invasive carcinoma | F362F | Silent | 1 |
| BRCA | Breast invasive carcinoma | G363R | Missense | 1 |
| BRCA | Breast invasive carcinoma | R214C | Missense | 1 |
| BRCA | Breast invasive carcinoma | T152M | Missense | 1 |
| COAD | Colon adenocarcinoma | A340A | Silent | 1 |
| COAD | Colon adenocarcinoma | A503V | Missense | 1 |
| COAD | Colon adenocarcinoma | D63N | Missense | 1 |
| COAD | Colon adenocarcinoma | L456R | Missense | 1 |
| COAD | Colon adenocarcinoma | P310S | Missense | 1 |
| COAD | Colon adenocarcinoma | R166W | Missense | 1 |
| COAD | Colon adenocarcinoma | R229W | Missense | 1 |
| COAD | Colon adenocarcinoma | R248C | Missense | 1 |
| COAD | Colon adenocarcinoma | R346Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R375C | Missense | 1 |
| COAD | Colon adenocarcinoma | R404R | Silent | 1 |
| COAD | Colon adenocarcinoma | R406* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | T435A | Missense | 1 |
| ESCA | Esophageal carcinoma | A463T | Missense | 1 |
| ESCA | Esophageal carcinoma | P294T | Missense | 1 |
| ESCA | Esophageal carcinoma | R248H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K558K | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L69F | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P470L | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | P466P | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | P561P | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | V47V | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | R253H | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R369C | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | P294P | Silent | 1 |
| LUAD | Lung adenocarcinoma | C191F | Missense | 1 |
| LUAD | Lung adenocarcinoma | E508* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | G364C | Missense | 1 |
| LUAD | Lung adenocarcinoma | G54D | Missense | 1 |
| LUAD | Lung adenocarcinoma | H239L | Missense | 1 |
| LUAD | Lung adenocarcinoma | M278T | Missense | 1 |
| LUAD | Lung adenocarcinoma | T454S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | K538K | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | L456R | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | V321I | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | Q103Q | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | R404H | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R18H | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A503V | Missense | 1 |
| PRAD | Prostate adenocarcinoma | P310P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | A73A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P284L | Missense | 1 |
| STAD | Stomach adenocarcinoma | A556T | Missense | 1 |
| STAD | Stomach adenocarcinoma | D358N | Missense | 1 |
| STAD | Stomach adenocarcinoma | P423L | Missense | 1 |
| STAD | Stomach adenocarcinoma | R229W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R248H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R346W | Missense | 1 |
| STAD | Stomach adenocarcinoma | T435A | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | A437D | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | L456P | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | Y34H | Missense | 1 |
| THCA | Thyroid carcinoma | P128S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C188S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L216L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L61I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R169K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R17C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R18H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R18R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R229L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R22H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R369C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R375C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V520I | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 14.1 | 33.3 |
| BRCA | Breast invasive carcinoma | 976 | 13.3 | 4.7 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 0 | 0 |
| COAD | Colon adenocarcinoma | 367 | 13.3 | 15.6 | 33.3 |
| ESCA | Esophageal carcinoma | 185 | 0 | 4.7 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 6.7 | 3.1 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 20 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 1.6 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 1.6 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 6.7 | 0 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 0 | 9.4 | 33.3 |
| LUSC | Lung squamous cell carcinoma | 177 | 6.7 | 3.1 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 6.7 | 1.6 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 1.6 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 6.7 | 1.6 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 0 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 6.7 | 1.6 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 0 | 10.9 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 4.7 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 1.6 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 13.3 | 18.8 | 0 |