Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| CESC | Cervical and endocervical cancers | K202K | Silent | 2 |
| BLCA | Bladder urothelial carcinoma | K124N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q103H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q128Q | Silent | 1 |
| BRCA | Breast invasive carcinoma | E7K | Missense | 1 |
| BRCA | Breast invasive carcinoma | L143L | Silent | 1 |
| BRCA | Breast invasive carcinoma | L177Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | N87S | Missense | 1 |
| BRCA | Breast invasive carcinoma | T66T | Silent | 1 |
| CESC | Cervical and endocervical cancers | L243L | Silent | 1 |
| COAD | Colon adenocarcinoma | A199T | Missense | 1 |
| COAD | Colon adenocarcinoma | D246D | Silent | 1 |
| COAD | Colon adenocarcinoma | N87N | Silent | 1 |
| COAD | Colon adenocarcinoma | P12P | Silent | 1 |
| ESCA | Esophageal carcinoma | D285E | Missense | 1 |
| GBM | Glioblastoma multiforme | A260A | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K157K | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K41N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K73K | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L196L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | N209S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R80R | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Y83Y | Silent | 1 |
| LGG | Brain Lower Grade Glioma | D274D | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | A242S | Missense | 1 |
| LUAD | Lung adenocarcinoma | E268K | Missense | 1 |
| LUAD | Lung adenocarcinoma | L243L | Silent | 1 |
| LUAD | Lung adenocarcinoma | V251L | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | D246H | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A267V | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R102C | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R65S | Missense | 1 |
| READ | Rectum adenocarcinoma | E7K | Missense | 1 |
| SARC | Sarcoma | S85F | Missense | 1 |
| SARC | Sarcoma | T97M | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A255A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | D274H | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E279K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F218F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P191L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P204L | Missense | 1 |
| STAD | Stomach adenocarcinoma | A184V | Missense | 1 |
| STAD | Stomach adenocarcinoma | A260V | Missense | 1 |
| STAD | Stomach adenocarcinoma | A267S | Missense | 1 |
| STAD | Stomach adenocarcinoma | A98T | Missense | 1 |
| STAD | Stomach adenocarcinoma | D270D | Silent | 1 |
| STAD | Stomach adenocarcinoma | D271N | Missense | 1 |
| STAD | Stomach adenocarcinoma | E7* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | L208F | Missense | 1 |
| STAD | Stomach adenocarcinoma | P204P | Silent | 1 |
| STAD | Stomach adenocarcinoma | R65H | Missense | 1 |
| STAD | Stomach adenocarcinoma | S77N | Missense | 1 |
| STAD | Stomach adenocarcinoma | T211M | Missense | 1 |
| STAD | Stomach adenocarcinoma | V291V | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I115M | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 4.5 | 6.1 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 9.1 | 9.1 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 13.6 | 0 | 0 |
| COAD | Colon adenocarcinoma | 367 | 13.6 | 3 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 3 | 0 |
| GBM | Glioblastoma multiforme | 283 | 4.5 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 22.7 | 6.1 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 4.5 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 3 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 4.5 | 6.1 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 0 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 3 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 3 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 6.1 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 3 | 0 |
| SARC | Sarcoma | 247 | 0 | 6.1 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 9.1 | 12.1 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 13.6 | 27.3 | 100 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 0 | 3 | 0 |