Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | I151M | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K244K | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L371L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L579L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | N206K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R92T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S123L | Missense | 1 |
| BRCA | Breast invasive carcinoma | F225F | Silent | 1 |
| BRCA | Breast invasive carcinoma | R406Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | V20I | Missense | 1 |
| CESC | Cervical and endocervical cancers | E533* | Nonsense | 1 |
| CESC | Cervical and endocervical cancers | K311T | Missense | 1 |
| COAD | Colon adenocarcinoma | G47R | Missense | 1 |
| COAD | Colon adenocarcinoma | G507S | Missense | 1 |
| COAD | Colon adenocarcinoma | K565T | Missense | 1 |
| COAD | Colon adenocarcinoma | M473I | Missense | 1 |
| COAD | Colon adenocarcinoma | N131N | Silent | 1 |
| COAD | Colon adenocarcinoma | N131S | Missense | 1 |
| COAD | Colon adenocarcinoma | R512W | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D221H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S262I | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | L459L | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | Y422H | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | L124R | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | P476T | Missense | 1 |
| LGG | Brain Lower Grade Glioma | M54I | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | F548L | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | H574L | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | I333L | Missense | 1 |
| LUAD | Lung adenocarcinoma | L506V | Missense | 1 |
| LUAD | Lung adenocarcinoma | L9L | Silent | 1 |
| LUAD | Lung adenocarcinoma | R251M | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | A494T | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E501Q | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | K340R | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | R492T | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | V302V | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | A513T | Missense | 1 |
| PRAD | Prostate adenocarcinoma | P191P | Silent | 1 |
| READ | Rectum adenocarcinoma | I404T | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | K252* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | M53I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R119R | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R181G | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R442W | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R468R | Silent | 1 |
| STAD | Stomach adenocarcinoma | F323V | Missense | 1 |
| STAD | Stomach adenocarcinoma | K117T | Missense | 1 |
| STAD | Stomach adenocarcinoma | P63S | Missense | 1 |
| STAD | Stomach adenocarcinoma | S415S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E48* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I358I | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P440H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R378C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R83C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S123* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S135Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S266Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T21A | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 23.1 | 9.5 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 7.7 | 4.8 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 2.4 | 25 |
| COAD | Colon adenocarcinoma | 367 | 7.7 | 14.3 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 0 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 4.8 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 7.7 | 2.4 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 4.8 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 2.4 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 7.1 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 7.7 | 4.8 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 4.8 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 7.7 | 4.8 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 2.4 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 7.7 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 2.4 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 15.4 | 7.1 | 25 |
| STAD | Stomach adenocarcinoma | 393 | 7.7 | 7.1 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 7.7 | 14.3 | 50 |