Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| SKCM | Skin Cutaneous Melanoma | F1264F | Silent | 2 |
| SKCM | Skin Cutaneous Melanoma | H899Y | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | P436S | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | P697S | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | A134P | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D1479N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E1406Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E48Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | H153Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | H419N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I453M | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L407L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L667F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | M310I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P261S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P265T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P508R | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R641Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S495* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | T818M | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V928V | Silent | 1 |
| BRCA | Breast invasive carcinoma | A1125V | Missense | 1 |
| BRCA | Breast invasive carcinoma | E1178K | Missense | 1 |
| BRCA | Breast invasive carcinoma | E1200* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | L1134L | Silent | 1 |
| BRCA | Breast invasive carcinoma | M391I | Missense | 1 |
| BRCA | Breast invasive carcinoma | M744I | Missense | 1 |
| BRCA | Breast invasive carcinoma | N735N | Silent | 1 |
| BRCA | Breast invasive carcinoma | S920N | Missense | 1 |
| CESC | Cervical and endocervical cancers | E1243K | Missense | 1 |
| CESC | Cervical and endocervical cancers | Q1196Q | Silent | 1 |
| CESC | Cervical and endocervical cancers | S212C | Missense | 1 |
| CESC | Cervical and endocervical cancers | S263Y | Missense | 1 |
| COAD | Colon adenocarcinoma | A1005D | Missense | 1 |
| COAD | Colon adenocarcinoma | A1142V | Missense | 1 |
| COAD | Colon adenocarcinoma | A994A | Silent | 1 |
| COAD | Colon adenocarcinoma | D1082G | Missense | 1 |
| COAD | Colon adenocarcinoma | F1126S | Missense | 1 |
| COAD | Colon adenocarcinoma | F472S | Missense | 1 |
| COAD | Colon adenocarcinoma | G1302V | Missense | 1 |
| COAD | Colon adenocarcinoma | G1395* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | G868G | Silent | 1 |
| COAD | Colon adenocarcinoma | G886W | Missense | 1 |
| COAD | Colon adenocarcinoma | I106S | Missense | 1 |
| COAD | Colon adenocarcinoma | I486V | Missense | 1 |
| COAD | Colon adenocarcinoma | I565I | Silent | 1 |
| COAD | Colon adenocarcinoma | K1343R | Missense | 1 |
| COAD | Colon adenocarcinoma | L1240L | Silent | 1 |
| COAD | Colon adenocarcinoma | L70I | Missense | 1 |
| COAD | Colon adenocarcinoma | P333P | Silent | 1 |
| COAD | Colon adenocarcinoma | P475S | Missense | 1 |
| COAD | Colon adenocarcinoma | P476L | Missense | 1 |
| COAD | Colon adenocarcinoma | Q388R | Missense | 1 |
| COAD | Colon adenocarcinoma | R501R | Silent | 1 |
| COAD | Colon adenocarcinoma | S1328Y | Missense | 1 |
| COAD | Colon adenocarcinoma | S264R | Missense | 1 |
| COAD | Colon adenocarcinoma | S925Y | Missense | 1 |
| COAD | Colon adenocarcinoma | T634T | Silent | 1 |
| COAD | Colon adenocarcinoma | V29V | Silent | 1 |
| ESCA | Esophageal carcinoma | E88* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | G228A | Missense | 1 |
| ESCA | Esophageal carcinoma | P272H | Missense | 1 |
| ESCA | Esophageal carcinoma | Q1113P | Missense | 1 |
| ESCA | Esophageal carcinoma | Q990R | Missense | 1 |
| ESCA | Esophageal carcinoma | R1252R | Silent | 1 |
| ESCA | Esophageal carcinoma | T964S | Missense | 1 |
| GBM | Glioblastoma multiforme | D57N | Missense | 1 |
| GBM | Glioblastoma multiforme | G1386G | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E1200K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L934V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | N777N | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P341P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q987P | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R1296* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R325L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S1351R | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S206N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V1330V | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V477V | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | L780L | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | E1278K | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | N176D | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | P1380P | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | S952L | Missense | 1 |
| LGG | Brain Lower Grade Glioma | S920G | Missense | 1 |
| LGG | Brain Lower Grade Glioma | V748A | Missense | 1 |
| LGG | Brain Lower Grade Glioma | V759M | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | F696L | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | L938V | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | M1468V | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | N1208K | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | N166N | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | S678S | Silent | 1 |
| LUAD | Lung adenocarcinoma | A725T | Missense | 1 |
| LUAD | Lung adenocarcinoma | E1200* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | E1432D | Missense | 1 |
| LUAD | Lung adenocarcinoma | E454D | Missense | 1 |
| LUAD | Lung adenocarcinoma | G1220C | Missense | 1 |
| LUAD | Lung adenocarcinoma | G1448R | Missense | 1 |
| LUAD | Lung adenocarcinoma | G684* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | H961R | Missense | 1 |
| LUAD | Lung adenocarcinoma | L44L | Silent | 1 |
| LUAD | Lung adenocarcinoma | L667F | Missense | 1 |
| LUAD | Lung adenocarcinoma | M1149L | Missense | 1 |
| LUAD | Lung adenocarcinoma | M391I | Missense | 1 |
| LUAD | Lung adenocarcinoma | P1061L | Missense | 1 |
| LUAD | Lung adenocarcinoma | P1133L | Missense | 1 |
| LUAD | Lung adenocarcinoma | P1167P | Silent | 1 |
| LUAD | Lung adenocarcinoma | P167S | Missense | 1 |
| LUAD | Lung adenocarcinoma | P721P | Silent | 1 |
| LUAD | Lung adenocarcinoma | R1162I | Missense | 1 |
| LUAD | Lung adenocarcinoma | S1084F | Missense | 1 |
| LUAD | Lung adenocarcinoma | S1084S | Silent | 1 |
| LUAD | Lung adenocarcinoma | S152C | Missense | 1 |
| LUAD | Lung adenocarcinoma | S537C | Missense | 1 |
| LUAD | Lung adenocarcinoma | T835A | Missense | 1 |
| LUAD | Lung adenocarcinoma | T862R | Missense | 1 |
| LUAD | Lung adenocarcinoma | V1071V | Silent | 1 |
| LUAD | Lung adenocarcinoma | V1085I | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | D1155Y | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E1183Q | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G447E | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G724E | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | I323M | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | I828F | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | N254Y | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P1367A | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S917G | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S968* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | T319S | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | D1082Y | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | G1302G | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | H382P | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | L1434L | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | P1080L | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A1142V | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A994A | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | D1407D | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | E1406* | Nonsense | 1 |
| PAAD | Pancreatic adenocarcinoma | G612D | Missense | 1 |
| PCPG | Pheochromocytoma and Paraganglioma | G800D | Missense | 1 |
| PCPG | Pheochromocytoma and Paraganglioma | P822R | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R104K | Missense | 1 |
| PRAD | Prostate adenocarcinoma | V1234V | Silent | 1 |
| READ | Rectum adenocarcinoma | G1386G | Silent | 1 |
| READ | Rectum adenocarcinoma | R1165W | Missense | 1 |
| READ | Rectum adenocarcinoma | R1252I | Missense | 1 |
| SARC | Sarcoma | P977S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A108E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A118A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | E1262K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F1340C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F472F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G1395R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G947R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H1218Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I1222I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | I1393I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | I375I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | I924I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L1049R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L1403I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L407L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L687L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L963L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L966L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P1042S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1045L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P119S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1203P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P145S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P17L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P313L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P350S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P365S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P368S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P402S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P438L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P476L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P625S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P681S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P890S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P911S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P978L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q1070Q | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | Q1310* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q458* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | R1441W | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R659K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1321F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S462L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S512F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S512S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S695L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S806F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S820S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | T496A | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | V1440V | Silent | 1 |
| STAD | Stomach adenocarcinoma | A1128V | Missense | 1 |
| STAD | Stomach adenocarcinoma | G1079G | Silent | 1 |
| STAD | Stomach adenocarcinoma | G1470W | Missense | 1 |
| STAD | Stomach adenocarcinoma | H1289Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | K1174E | Missense | 1 |
| STAD | Stomach adenocarcinoma | K1211K | Silent | 1 |
| STAD | Stomach adenocarcinoma | K1270E | Missense | 1 |
| STAD | Stomach adenocarcinoma | L55F | Missense | 1 |
| STAD | Stomach adenocarcinoma | L579* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | N915Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | P1061P | Silent | 1 |
| STAD | Stomach adenocarcinoma | R1252I | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1299W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R28H | Missense | 1 |
| STAD | Stomach adenocarcinoma | S159Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | S700P | Missense | 1 |
| STAD | Stomach adenocarcinoma | V769A | Missense | 1 |
| STAD | Stomach adenocarcinoma | V769I | Missense | 1 |
| STAD | Stomach adenocarcinoma | V869I | Missense | 1 |
| THCA | Thyroid carcinoma | S906P | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A758V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C1003C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E1213K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G1220G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G868G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | H281Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I486T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L1166L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L361F | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L43V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L632L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N523K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N745K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N765S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P475Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P753H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q49* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q661L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1296Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R141W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S318P | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S492S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S702Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S968L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S968S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T411A | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T664M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T862A | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T86I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V1076I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V1389V | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y53C | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 3.2 | 7.8 | 7.7 |
| BRCA | Breast invasive carcinoma | 976 | 3.2 | 2.8 | 7.7 |
| CESC | Cervical and endocervical cancers | 194 | 1.6 | 1.7 | 0 |
| COAD | Colon adenocarcinoma | 367 | 12.9 | 9.5 | 7.7 |
| ESCA | Esophageal carcinoma | 185 | 1.6 | 2.8 | 7.7 |
| GBM | Glioblastoma multiforme | 283 | 1.6 | 0.6 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 6.5 | 3.4 | 7.7 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 1.6 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 1.6 | 1.7 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 1.7 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 3.2 | 2.2 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 8.1 | 10.6 | 15.4 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 5.6 | 7.7 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 3.2 | 1.7 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 3.2 | 1.1 | 7.7 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 1.1 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 1.6 | 0.6 | 0 |
| READ | Rectum adenocarcinoma | 122 | 1.6 | 1.1 | 0 |
| SARC | Sarcoma | 247 | 0 | 0.6 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 27.4 | 21.8 | 15.4 |
| STAD | Stomach adenocarcinoma | 393 | 4.8 | 8.4 | 7.7 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0.6 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 12.9 | 12.8 | 7.7 |