Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | G413R | Missense | 3 |
| COAD | Colon adenocarcinoma | Q556R | Missense | 2 |
| COAD | Colon adenocarcinoma | T366I | Missense | 2 |
| READ | Rectum adenocarcinoma | G413* | Nonsense | 2 |
| BLCA | Bladder urothelial carcinoma | E213Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | F351L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L503V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P488S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q379H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R303Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R493C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V304I | Missense | 1 |
| BRCA | Breast invasive carcinoma | E320G | Missense | 1 |
| BRCA | Breast invasive carcinoma | E531K | Missense | 1 |
| BRCA | Breast invasive carcinoma | I476T | Missense | 1 |
| BRCA | Breast invasive carcinoma | L107I | Missense | 1 |
| BRCA | Breast invasive carcinoma | M289I | Missense | 1 |
| BRCA | Breast invasive carcinoma | R516Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | E213Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | F384F | Silent | 1 |
| CESC | Cervical and endocervical cancers | R246T | Missense | 1 |
| CESC | Cervical and endocervical cancers | S14S | Silent | 1 |
| CESC | Cervical and endocervical cancers | W193C | Missense | 1 |
| COAD | Colon adenocarcinoma | G413G | Silent | 1 |
| COAD | Colon adenocarcinoma | K585N | Missense | 1 |
| COAD | Colon adenocarcinoma | P164S | Missense | 1 |
| COAD | Colon adenocarcinoma | Q556Q | Silent | 1 |
| COAD | Colon adenocarcinoma | S322S | Silent | 1 |
| COAD | Colon adenocarcinoma | S75S | Silent | 1 |
| COAD | Colon adenocarcinoma | V191V | Silent | 1 |
| COAD | Colon adenocarcinoma | W255C | Missense | 1 |
| ESCA | Esophageal carcinoma | G495A | Missense | 1 |
| ESCA | Esophageal carcinoma | K461N | Missense | 1 |
| ESCA | Esophageal carcinoma | N128S | Missense | 1 |
| GBM | Glioblastoma multiforme | Q556Q | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | H490D | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | I393V | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | F364I | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | N223N | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | M51R | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | K48E | Missense | 1 |
| LUAD | Lung adenocarcinoma | A257A | Silent | 1 |
| LUAD | Lung adenocarcinoma | D324D | Silent | 1 |
| LUAD | Lung adenocarcinoma | R520C | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P245T | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | G413V | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | Q556Q | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | G427E | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | S428Y | Missense | 1 |
| SARC | Sarcoma | F384F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | K358K | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L398F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P456L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R507R | Silent | 1 |
| STAD | Stomach adenocarcinoma | E213G | Missense | 1 |
| STAD | Stomach adenocarcinoma | R520H | Missense | 1 |
| STAD | Stomach adenocarcinoma | T183A | Missense | 1 |
| STAD | Stomach adenocarcinoma | T326A | Missense | 1 |
| THYM | Thymoma | P33R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D534D | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L398I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V443V | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 16.7 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 12.5 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 11.8 | 6.2 | 0 |
| COAD | Colon adenocarcinoma | 367 | 29.4 | 20.8 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 6.2 | 0 |
| GBM | Glioblastoma multiforme | 283 | 5.9 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 4.2 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 5.9 | 2.1 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 2.1 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 2.1 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 11.8 | 2.1 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 2.1 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 5.9 | 2.1 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 4.2 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 0 | 100 |
| SARC | Sarcoma | 247 | 5.9 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 11.8 | 4.2 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 0 | 8.3 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 2.1 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 11.8 | 2.1 | 0 |