Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| SKCM | Skin Cutaneous Melanoma | G93E | Missense | 3 |
| SKCM | Skin Cutaneous Melanoma | S529L | Missense | 3 |
| PRAD | Prostate adenocarcinoma | R718Q | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | D586N | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | D73N | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | E101K | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | E618K | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | F841F | Silent | 2 |
| SKCM | Skin Cutaneous Melanoma | G364G | Silent | 2 |
| SKCM | Skin Cutaneous Melanoma | G614E | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | G720E | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | K543K | Silent | 2 |
| SKCM | Skin Cutaneous Melanoma | P258S | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | P308S | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | P85S | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | R560Q | Missense | 2 |
| SKCM | Skin Cutaneous Melanoma | S300F | Missense | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R205S | Missense | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R741Q | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | C23* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | D264Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E240K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E461Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E653Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E657Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E895K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E895V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | F282V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L148L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L175L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L660F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | M94L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P43S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q199* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | Q44* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | R83G | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S328* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | S409L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S760L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Y21C | Missense | 1 |
| BRCA | Breast invasive carcinoma | A1030A | Silent | 1 |
| BRCA | Breast invasive carcinoma | A180A | Silent | 1 |
| BRCA | Breast invasive carcinoma | A465A | Silent | 1 |
| BRCA | Breast invasive carcinoma | A500D | Missense | 1 |
| BRCA | Breast invasive carcinoma | C754C | Silent | 1 |
| BRCA | Breast invasive carcinoma | D31H | Missense | 1 |
| BRCA | Breast invasive carcinoma | D877D | Silent | 1 |
| BRCA | Breast invasive carcinoma | P75T | Missense | 1 |
| BRCA | Breast invasive carcinoma | Q439P | Missense | 1 |
| BRCA | Breast invasive carcinoma | R22C | Missense | 1 |
| BRCA | Breast invasive carcinoma | S172L | Missense | 1 |
| BRCA | Breast invasive carcinoma | Y197H | Missense | 1 |
| CESC | Cervical and endocervical cancers | C213W | Missense | 1 |
| CESC | Cervical and endocervical cancers | D624H | Missense | 1 |
| CESC | Cervical and endocervical cancers | E694K | Missense | 1 |
| COAD | Colon adenocarcinoma | A1031A | Silent | 1 |
| COAD | Colon adenocarcinoma | A154T | Missense | 1 |
| COAD | Colon adenocarcinoma | A296T | Missense | 1 |
| COAD | Colon adenocarcinoma | A465A | Silent | 1 |
| COAD | Colon adenocarcinoma | D919D | Silent | 1 |
| COAD | Colon adenocarcinoma | D919N | Missense | 1 |
| COAD | Colon adenocarcinoma | E4K | Missense | 1 |
| COAD | Colon adenocarcinoma | L371L | Silent | 1 |
| COAD | Colon adenocarcinoma | M702I | Missense | 1 |
| COAD | Colon adenocarcinoma | P935P | Silent | 1 |
| COAD | Colon adenocarcinoma | R120C | Missense | 1 |
| COAD | Colon adenocarcinoma | R120H | Missense | 1 |
| COAD | Colon adenocarcinoma | R772C | Missense | 1 |
| COAD | Colon adenocarcinoma | R839* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | S172L | Missense | 1 |
| COAD | Colon adenocarcinoma | S409L | Missense | 1 |
| COAD | Colon adenocarcinoma | V269V | Silent | 1 |
| ESCA | Esophageal carcinoma | D677V | Missense | 1 |
| ESCA | Esophageal carcinoma | P77A | Missense | 1 |
| ESCA | Esophageal carcinoma | R723R | Silent | 1 |
| ESCA | Esophageal carcinoma | T567I | Missense | 1 |
| GBM | Glioblastoma multiforme | C23C | Silent | 1 |
| GBM | Glioblastoma multiforme | G310S | Missense | 1 |
| GBM | Glioblastoma multiforme | G89W | Missense | 1 |
| GBM | Glioblastoma multiforme | N616N | Silent | 1 |
| GBM | Glioblastoma multiforme | P304L | Missense | 1 |
| GBM | Glioblastoma multiforme | R853K | Missense | 1 |
| GBM | Glioblastoma multiforme | S3S | Silent | 1 |
| GBM | Glioblastoma multiforme | S409S | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A157A | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A32S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E374K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E928* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | F226L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | F431F | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G249* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G410D | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | I899V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q989K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R151R | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R604Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R772H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S172S | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V155V | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Y281C | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | M430I | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | V470L | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | W1023* | Nonsense | 1 |
| LGG | Brain Lower Grade Glioma | A1035V | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A211V | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A465V | Missense | 1 |
| LGG | Brain Lower Grade Glioma | E940G | Missense | 1 |
| LGG | Brain Lower Grade Glioma | G806G | Silent | 1 |
| LGG | Brain Lower Grade Glioma | K110N | Missense | 1 |
| LGG | Brain Lower Grade Glioma | P258H | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R148Q | Missense | 1 |
| LGG | Brain Lower Grade Glioma | S3S | Silent | 1 |
| LGG | Brain Lower Grade Glioma | T229M | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | G34E | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | G946A | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | H952R | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | N113I | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | N233Y | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | P568A | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | R723R | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | S127C | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S172S | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | S48Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | A481S | Missense | 1 |
| LUAD | Lung adenocarcinoma | C729S | Missense | 1 |
| LUAD | Lung adenocarcinoma | D412H | Missense | 1 |
| LUAD | Lung adenocarcinoma | E418K | Missense | 1 |
| LUAD | Lung adenocarcinoma | G107G | Silent | 1 |
| LUAD | Lung adenocarcinoma | I76S | Missense | 1 |
| LUAD | Lung adenocarcinoma | K92E | Missense | 1 |
| LUAD | Lung adenocarcinoma | L660F | Missense | 1 |
| LUAD | Lung adenocarcinoma | N42S | Missense | 1 |
| LUAD | Lung adenocarcinoma | R661M | Missense | 1 |
| LUAD | Lung adenocarcinoma | S487S | Silent | 1 |
| LUAD | Lung adenocarcinoma | S910R | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | A279S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E4K | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E55K | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | N844K | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R706S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R839L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | T649T | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | T680T | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | T909A | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | D119Y | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | M702V | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | N795S | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A595D | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A926T | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | N738D | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | P709S | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | P990T | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R6K | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | T73T | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | V363I | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A246A | Silent | 1 |
| PRAD | Prostate adenocarcinoma | A707V | Missense | 1 |
| PRAD | Prostate adenocarcinoma | M1002I | Missense | 1 |
| PRAD | Prostate adenocarcinoma | S814L | Missense | 1 |
| PRAD | Prostate adenocarcinoma | S934Y | Missense | 1 |
| READ | Rectum adenocarcinoma | M859I | Missense | 1 |
| READ | Rectum adenocarcinoma | R772C | Missense | 1 |
| SARC | Sarcoma | D142N | Missense | 1 |
| SARC | Sarcoma | E940K | Missense | 1 |
| SARC | Sarcoma | F761Y | Missense | 1 |
| SARC | Sarcoma | P13S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A1030V | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A825A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | D169N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D395N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D420N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D638N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D881N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E104K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E240E | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | E240K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E27K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E722K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E778K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E821K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F188F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G249E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G298R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G486D | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G548D | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G611E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G901E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G904E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G915E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H1013Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I100I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | I126I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | I74I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | K905K | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L394I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L490L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L509L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | M534I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | N202N | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | N66I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P288S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P308L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P43L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P508L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P523S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P570S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P603S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P634S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P734S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P77S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q546K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R798K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R839Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R963R | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S1020F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S127N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S144N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S172L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S201L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S231F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S322F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S40S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S626F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S698L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S814L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T46S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T73T | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | V155V | Silent | 1 |
| STAD | Stomach adenocarcinoma | A1030V | Missense | 1 |
| STAD | Stomach adenocarcinoma | D472H | Missense | 1 |
| STAD | Stomach adenocarcinoma | E914* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | G611G | Silent | 1 |
| STAD | Stomach adenocarcinoma | K265R | Missense | 1 |
| STAD | Stomach adenocarcinoma | N145S | Missense | 1 |
| STAD | Stomach adenocarcinoma | P22S | Missense | 1 |
| STAD | Stomach adenocarcinoma | P67P | Silent | 1 |
| STAD | Stomach adenocarcinoma | R148W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R158Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | S173S | Silent | 1 |
| STAD | Stomach adenocarcinoma | S529S | Silent | 1 |
| STAD | Stomach adenocarcinoma | T73T | Silent | 1 |
| THYM | Thymoma | M29T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A12T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A654D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E882G | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L800L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P990L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R120C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R205G | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R208C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R735R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R83* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T168M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T168T | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T229R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V617V | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 3.2 | 7.3 | 40 |
| BRCA | Breast invasive carcinoma | 976 | 8.1 | 3.4 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 1.5 | 0 |
| COAD | Colon adenocarcinoma | 367 | 9.7 | 4.9 | 10 |
| ESCA | Esophageal carcinoma | 185 | 1.6 | 1.5 | 0 |
| GBM | Glioblastoma multiforme | 283 | 6.5 | 2 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 8.1 | 4.4 | 20 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 1 | 10 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 3.2 | 3.9 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 3.2 | 3.9 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 3.2 | 4.9 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 3.2 | 3.4 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 1.5 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 1.6 | 3.4 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 1.6 | 2.9 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 1 | 0 |
| SARC | Sarcoma | 247 | 0 | 2 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 32.3 | 37.1 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 8.1 | 3.4 | 10 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0.5 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 6.5 | 6.3 | 10 |