Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | G231C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | H177D | Missense | 1 |
| BRCA | Breast invasive carcinoma | C176* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | L97L | Silent | 1 |
| BRCA | Breast invasive carcinoma | R127K | Missense | 1 |
| BRCA | Breast invasive carcinoma | S183S | Silent | 1 |
| CESC | Cervical and endocervical cancers | G204R | Missense | 1 |
| COAD | Colon adenocarcinoma | C55Y | Missense | 1 |
| COAD | Colon adenocarcinoma | I107V | Missense | 1 |
| COAD | Colon adenocarcinoma | R40H | Missense | 1 |
| GBM | Glioblastoma multiforme | A82V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G162A | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L207F | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R166K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S230A | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S230L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S230S | Silent | 1 |
| LGG | Brain Lower Grade Glioma | L97L | Silent | 1 |
| LUAD | Lung adenocarcinoma | A158A | Silent | 1 |
| LUAD | Lung adenocarcinoma | Q146* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | R40C | Missense | 1 |
| LUAD | Lung adenocarcinoma | T126T | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | P118L | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | I107I | Silent | 1 |
| PRAD | Prostate adenocarcinoma | P118P | Silent | 1 |
| READ | Rectum adenocarcinoma | E141* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | H60H | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | F101F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G191E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I107I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | K39R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P175S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P87L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | V75V | Silent | 1 |
| STAD | Stomach adenocarcinoma | A71T | Missense | 1 |
| STAD | Stomach adenocarcinoma | H116R | Missense | 1 |
| STAD | Stomach adenocarcinoma | K34R | Missense | 1 |
| STAD | Stomach adenocarcinoma | L148S | Missense | 1 |
| STAD | Stomach adenocarcinoma | R40H | Missense | 1 |
| THCA | Thyroid carcinoma | L97L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A158V | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 8 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 15.4 | 4 | 33.3 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 4 | 0 |
| COAD | Colon adenocarcinoma | 367 | 0 | 12 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 0 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 4 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 7.7 | 20 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 7.7 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 0 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 15.4 | 4 | 33.3 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 4 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 7.7 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 7.7 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 7.7 | 0 | 33.3 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 23.1 | 16 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 0 | 20 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 7.7 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 0 | 4 | 0 |