Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | D449H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E143Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E348Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E470K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E60Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E688Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K170K | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | K632N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L719L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | R202T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R236T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R327T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R412T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R755G | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V518M | Missense | 1 |
| BRCA | Breast invasive carcinoma | A564E | Missense | 1 |
| BRCA | Breast invasive carcinoma | A658V | Missense | 1 |
| BRCA | Breast invasive carcinoma | D811N | Missense | 1 |
| BRCA | Breast invasive carcinoma | E187* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | G601V | Missense | 1 |
| BRCA | Breast invasive carcinoma | K120N | Missense | 1 |
| BRCA | Breast invasive carcinoma | T240S | Missense | 1 |
| BRCA | Breast invasive carcinoma | V262G | Missense | 1 |
| CESC | Cervical and endocervical cancers | E523K | Missense | 1 |
| CESC | Cervical and endocervical cancers | E688Q | Missense | 1 |
| COAD | Colon adenocarcinoma | I784I | Silent | 1 |
| COAD | Colon adenocarcinoma | R330G | Missense | 1 |
| COAD | Colon adenocarcinoma | S204Y | Missense | 1 |
| COAD | Colon adenocarcinoma | T385M | Missense | 1 |
| ESCA | Esophageal carcinoma | A12T | Missense | 1 |
| ESCA | Esophageal carcinoma | D237V | Missense | 1 |
| ESCA | Esophageal carcinoma | D87N | Missense | 1 |
| ESCA | Esophageal carcinoma | G601V | Missense | 1 |
| ESCA | Esophageal carcinoma | G657* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | G800E | Missense | 1 |
| GBM | Glioblastoma multiforme | G634R | Missense | 1 |
| GBM | Glioblastoma multiforme | Y579C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E395K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | H308N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K214Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K232E | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K632N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q805H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S680* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | A47G | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | P184T | Missense | 1 |
| LGG | Brain Lower Grade Glioma | T324T | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | K229N | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | T649I | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | V662V | Silent | 1 |
| LUAD | Lung adenocarcinoma | D547H | Missense | 1 |
| LUAD | Lung adenocarcinoma | E289Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | E668K | Missense | 1 |
| LUAD | Lung adenocarcinoma | G397V | Missense | 1 |
| LUAD | Lung adenocarcinoma | L638L | Silent | 1 |
| LUAD | Lung adenocarcinoma | L714F | Missense | 1 |
| LUAD | Lung adenocarcinoma | R250T | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | L685L | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | R236T | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S525L | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | Q366E | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A609V | Missense | 1 |
| SARC | Sarcoma | W503L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E428K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I203F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P14S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S85L | Missense | 1 |
| STAD | Stomach adenocarcinoma | D615N | Missense | 1 |
| STAD | Stomach adenocarcinoma | E105G | Missense | 1 |
| STAD | Stomach adenocarcinoma | I682I | Silent | 1 |
| STAD | Stomach adenocarcinoma | N628N | Silent | 1 |
| STAD | Stomach adenocarcinoma | P92P | Silent | 1 |
| STAD | Stomach adenocarcinoma | S316N | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | A47A | Silent | 1 |
| THCA | Thyroid carcinoma | K247* | Nonsense | 1 |
| THYM | Thymoma | R422K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A658V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A796P | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D237Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D325N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D717N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E146* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F353L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I734M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L534S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L685L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N459N | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P801L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R741C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V258V | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V359M | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 14.3 | 18.1 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 9.7 | 20 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 2.8 | 0 |
| COAD | Colon adenocarcinoma | 367 | 7.1 | 4.2 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 6.9 | 20 |
| GBM | Glioblastoma multiforme | 283 | 0 | 2.8 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 8.3 | 20 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 2.8 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 7.1 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 7.1 | 2.8 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 7.1 | 8.3 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 7.1 | 2.8 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 1.4 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 1.4 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 0 | 0 |
| SARC | Sarcoma | 247 | 0 | 1.4 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 0 | 5.6 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 21.4 | 4.2 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 7.1 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 20 |
| THYM | Thymoma | 119 | 0 | 1.4 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 21.4 | 15.3 | 20 |