Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| LIHC | Liver hepatocellular carcinoma | P90S | Missense | 3 |
| BLCA | Bladder urothelial carcinoma | E292Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K678N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R445L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S673* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | T564M | Missense | 1 |
| CESC | Cervical and endocervical cancers | R445H | Missense | 1 |
| CESC | Cervical and endocervical cancers | T120M | Missense | 1 |
| COAD | Colon adenocarcinoma | F296F | Silent | 1 |
| COAD | Colon adenocarcinoma | F658L | Missense | 1 |
| COAD | Colon adenocarcinoma | G610R | Missense | 1 |
| COAD | Colon adenocarcinoma | R234Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R415C | Missense | 1 |
| COAD | Colon adenocarcinoma | S241S | Silent | 1 |
| COAD | Colon adenocarcinoma | T380M | Missense | 1 |
| ESCA | Esophageal carcinoma | D190E | Missense | 1 |
| ESCA | Esophageal carcinoma | Y328C | Missense | 1 |
| GBM | Glioblastoma multiforme | R646W | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A224S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A482T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E287Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E88E | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K158K | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P383P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R699W | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V706I | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E394D | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | N444I | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | T308M | Missense | 1 |
| LGG | Brain Lower Grade Glioma | C417C | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | P461R | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S520F | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | Y355C | Missense | 1 |
| LUAD | Lung adenocarcinoma | A119T | Missense | 1 |
| LUAD | Lung adenocarcinoma | E39D | Missense | 1 |
| LUAD | Lung adenocarcinoma | F471F | Silent | 1 |
| LUAD | Lung adenocarcinoma | I269I | Silent | 1 |
| LUAD | Lung adenocarcinoma | R491C | Missense | 1 |
| LUAD | Lung adenocarcinoma | S136S | Silent | 1 |
| LUAD | Lung adenocarcinoma | T54T | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | L295I | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | V12V | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | P357A | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | Y11Y | Silent | 1 |
| PRAD | Prostate adenocarcinoma | R683W | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D708N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H259Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I635I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | I713I | Silent | 1 |
| STAD | Stomach adenocarcinoma | A389A | Silent | 1 |
| STAD | Stomach adenocarcinoma | A612V | Missense | 1 |
| STAD | Stomach adenocarcinoma | A680T | Missense | 1 |
| STAD | Stomach adenocarcinoma | E488D | Missense | 1 |
| STAD | Stomach adenocarcinoma | G388E | Missense | 1 |
| STAD | Stomach adenocarcinoma | R483W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R669C | Missense | 1 |
| STAD | Stomach adenocarcinoma | R691C | Missense | 1 |
| STAD | Stomach adenocarcinoma | Y303Y | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A201V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A418T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D334N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | H451Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I210I | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P602S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y11Y | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y326* | Nonsense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 8.3 | 50 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 0 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 4.2 | 0 |
| COAD | Colon adenocarcinoma | 367 | 11.1 | 10.4 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 4.2 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 2.1 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 16.7 | 10.4 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 2.1 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 4.2 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 5.6 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 12.5 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 22.2 | 6.2 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 5.6 | 2.1 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 2.1 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 5.6 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 2.1 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 0 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 11.1 | 4.2 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 11.1 | 14.6 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 11.1 | 10.4 | 50 |