Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| OV | Ovarian serous cystadenocarcinoma | E113D | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | D328H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E146D | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E264K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L207V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L512V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L651V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P436L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R240S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R415W | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R536Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S435Y | Missense | 1 |
| BRCA | Breast invasive carcinoma | E146E | Silent | 1 |
| BRCA | Breast invasive carcinoma | M356I | Missense | 1 |
| BRCA | Breast invasive carcinoma | Q144* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | V638G | Missense | 1 |
| CESC | Cervical and endocervical cancers | K399N | Missense | 1 |
| COAD | Colon adenocarcinoma | D523Y | Missense | 1 |
| COAD | Colon adenocarcinoma | E113* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | K41T | Missense | 1 |
| COAD | Colon adenocarcinoma | L616I | Missense | 1 |
| COAD | Colon adenocarcinoma | R160H | Missense | 1 |
| COAD | Colon adenocarcinoma | R47W | Missense | 1 |
| COAD | Colon adenocarcinoma | R617Q | Missense | 1 |
| COAD | Colon adenocarcinoma | T109A | Missense | 1 |
| COAD | Colon adenocarcinoma | W381* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | G412E | Missense | 1 |
| ESCA | Esophageal carcinoma | Y483C | Missense | 1 |
| GBM | Glioblastoma multiforme | R262Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A503T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E163* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E264* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | I347I | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L117F | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | N450S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q154E | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q594H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S548F | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S573C | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | G74G | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | S433N | Missense | 1 |
| LAML | Acute Myeloid Leukemia | D289G | Missense | 1 |
| LAML | Acute Myeloid Leukemia | Y283C | Missense | 1 |
| LGG | Brain Lower Grade Glioma | D159Y | Missense | 1 |
| LGG | Brain Lower Grade Glioma | M625R | Missense | 1 |
| LGG | Brain Lower Grade Glioma | P604H | Missense | 1 |
| LGG | Brain Lower Grade Glioma | W297R | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | K247R | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | Q215* | Nonsense | 1 |
| LIHC | Liver hepatocellular carcinoma | R48H | Missense | 1 |
| LUAD | Lung adenocarcinoma | A526S | Missense | 1 |
| LUAD | Lung adenocarcinoma | E28Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | L461P | Missense | 1 |
| LUAD | Lung adenocarcinoma | M386I | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q292L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G582G | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | P384R | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R630P | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A392A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | A561A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | I347I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L45F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | N31N | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P535S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S496S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S573F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Y153H | Missense | 1 |
| STAD | Stomach adenocarcinoma | G567G | Silent | 1 |
| STAD | Stomach adenocarcinoma | I190I | Silent | 1 |
| STAD | Stomach adenocarcinoma | I520I | Silent | 1 |
| STAD | Stomach adenocarcinoma | Q255H | Missense | 1 |
| STAD | Stomach adenocarcinoma | S440S | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | E39Q | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | Y153Y | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A441T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A488V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q594Q | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R481Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R86R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V304F | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V665D | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 18.3 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 6.2 | 3.3 | 16.7 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 1.7 | 0 |
| COAD | Colon adenocarcinoma | 367 | 0 | 11.7 | 33.3 |
| ESCA | Esophageal carcinoma | 185 | 0 | 3.3 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 1.7 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 6.2 | 11.7 | 33.3 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 6.2 | 1.7 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 3.3 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 6.7 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 3.3 | 16.7 |
| LUAD | Lung adenocarcinoma | 533 | 0 | 8.3 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 6.2 | 0 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 5 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 1.7 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 0 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 31.2 | 6.7 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 25 | 1.7 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 6.2 | 1.7 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 12.5 | 8.3 | 0 |