Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | P470P | Silent | 2 |
| COAD | Colon adenocarcinoma | R201R | Silent | 2 |
| BLCA | Bladder urothelial carcinoma | L1176L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L715V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q651* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | R1169H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R1290G | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R81C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S1004C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S12Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S1382N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S266L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S471* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | S565F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | T360S | Missense | 1 |
| BRCA | Breast invasive carcinoma | A91A | Silent | 1 |
| BRCA | Breast invasive carcinoma | E85V | Missense | 1 |
| BRCA | Breast invasive carcinoma | G828G | Silent | 1 |
| BRCA | Breast invasive carcinoma | G978E | Missense | 1 |
| BRCA | Breast invasive carcinoma | L1243L | Silent | 1 |
| BRCA | Breast invasive carcinoma | L843L | Silent | 1 |
| BRCA | Breast invasive carcinoma | P235T | Missense | 1 |
| BRCA | Breast invasive carcinoma | P503P | Silent | 1 |
| BRCA | Breast invasive carcinoma | Q459* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | S655L | Missense | 1 |
| BRCA | Breast invasive carcinoma | V621V | Silent | 1 |
| CESC | Cervical and endocervical cancers | P11P | Silent | 1 |
| CESC | Cervical and endocervical cancers | Q1348* | Nonsense | 1 |
| CESC | Cervical and endocervical cancers | Q1348E | Missense | 1 |
| COAD | Colon adenocarcinoma | A536V | Missense | 1 |
| COAD | Colon adenocarcinoma | A704T | Missense | 1 |
| COAD | Colon adenocarcinoma | E189K | Missense | 1 |
| COAD | Colon adenocarcinoma | F270F | Silent | 1 |
| COAD | Colon adenocarcinoma | L1206P | Missense | 1 |
| COAD | Colon adenocarcinoma | L264I | Missense | 1 |
| COAD | Colon adenocarcinoma | L370L | Silent | 1 |
| COAD | Colon adenocarcinoma | M438T | Missense | 1 |
| COAD | Colon adenocarcinoma | M949I | Missense | 1 |
| COAD | Colon adenocarcinoma | P470H | Missense | 1 |
| COAD | Colon adenocarcinoma | Q1032R | Missense | 1 |
| COAD | Colon adenocarcinoma | Q1251R | Missense | 1 |
| COAD | Colon adenocarcinoma | Q1256* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | R1203C | Missense | 1 |
| COAD | Colon adenocarcinoma | R13W | Missense | 1 |
| COAD | Colon adenocarcinoma | R1461W | Missense | 1 |
| COAD | Colon adenocarcinoma | R201L | Missense | 1 |
| COAD | Colon adenocarcinoma | S512R | Missense | 1 |
| COAD | Colon adenocarcinoma | S716N | Missense | 1 |
| COAD | Colon adenocarcinoma | T1262N | Missense | 1 |
| COAD | Colon adenocarcinoma | T1319M | Missense | 1 |
| COAD | Colon adenocarcinoma | T361A | Missense | 1 |
| COAD | Colon adenocarcinoma | T825T | Silent | 1 |
| ESCA | Esophageal carcinoma | A253E | Missense | 1 |
| ESCA | Esophageal carcinoma | E1013Q | Missense | 1 |
| ESCA | Esophageal carcinoma | P67T | Missense | 1 |
| ESCA | Esophageal carcinoma | Q957* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | R201W | Missense | 1 |
| ESCA | Esophageal carcinoma | V961L | Missense | 1 |
| GBM | Glioblastoma multiforme | F441F | Silent | 1 |
| GBM | Glioblastoma multiforme | Q885H | Missense | 1 |
| GBM | Glioblastoma multiforme | R874* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D811V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E133V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G392E | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L346L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | M1394L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | M577L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q406K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R1290W | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R1329L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V963A | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E1013E | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | P760T | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | P901P | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | P956L | Missense | 1 |
| LGG | Brain Lower Grade Glioma | G1057D | Missense | 1 |
| LGG | Brain Lower Grade Glioma | K279K | Silent | 1 |
| LGG | Brain Lower Grade Glioma | R13M | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | E325G | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | G1281S | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | M569V | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | P11P | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | P1313P | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | P1429P | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | Q107H | Missense | 1 |
| LUAD | Lung adenocarcinoma | D113Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | G1363R | Missense | 1 |
| LUAD | Lung adenocarcinoma | G1376E | Missense | 1 |
| LUAD | Lung adenocarcinoma | G184V | Missense | 1 |
| LUAD | Lung adenocarcinoma | G344V | Missense | 1 |
| LUAD | Lung adenocarcinoma | G545W | Missense | 1 |
| LUAD | Lung adenocarcinoma | I839V | Missense | 1 |
| LUAD | Lung adenocarcinoma | L1218F | Missense | 1 |
| LUAD | Lung adenocarcinoma | L672F | Missense | 1 |
| LUAD | Lung adenocarcinoma | M652L | Missense | 1 |
| LUAD | Lung adenocarcinoma | P516A | Missense | 1 |
| LUAD | Lung adenocarcinoma | P654A | Missense | 1 |
| LUAD | Lung adenocarcinoma | R1088P | Missense | 1 |
| LUAD | Lung adenocarcinoma | R1162Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | R1290Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | R273R | Silent | 1 |
| LUAD | Lung adenocarcinoma | S269N | Missense | 1 |
| LUAD | Lung adenocarcinoma | T1316S | Missense | 1 |
| LUAD | Lung adenocarcinoma | V1416V | Silent | 1 |
| LUAD | Lung adenocarcinoma | Y160C | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | D811V | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E1013Q | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E189* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | G446E | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G545R | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P257P | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | P384L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | Q1082* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | Q365* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | R357L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R491H | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | V139L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | W296* | Nonsense | 1 |
| OV | Ovarian serous cystadenocarcinoma | L1206R | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | S444T | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | L147P | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | L154L | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | Q1237Q | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | S1164S | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | S399R | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | Y747Y | Silent | 1 |
| PRAD | Prostate adenocarcinoma | L552L | Silent | 1 |
| PRAD | Prostate adenocarcinoma | T1001M | Missense | 1 |
| PRAD | Prostate adenocarcinoma | V450V | Silent | 1 |
| READ | Rectum adenocarcinoma | A309V | Missense | 1 |
| READ | Rectum adenocarcinoma | F586L | Missense | 1 |
| READ | Rectum adenocarcinoma | N931H | Missense | 1 |
| READ | Rectum adenocarcinoma | R982Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E42K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F822F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | M1286I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1350L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P23S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P384L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P426S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P516L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P615S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P775S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P910S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R1169C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R1261Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1351S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S1425S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S565F | Missense | 1 |
| STAD | Stomach adenocarcinoma | A1070S | Missense | 1 |
| STAD | Stomach adenocarcinoma | A1166T | Missense | 1 |
| STAD | Stomach adenocarcinoma | A1357V | Missense | 1 |
| STAD | Stomach adenocarcinoma | A309V | Missense | 1 |
| STAD | Stomach adenocarcinoma | A348A | Silent | 1 |
| STAD | Stomach adenocarcinoma | A404A | Silent | 1 |
| STAD | Stomach adenocarcinoma | A90T | Missense | 1 |
| STAD | Stomach adenocarcinoma | D1121N | Missense | 1 |
| STAD | Stomach adenocarcinoma | D1451G | Missense | 1 |
| STAD | Stomach adenocarcinoma | D614N | Missense | 1 |
| STAD | Stomach adenocarcinoma | E75* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | G344D | Missense | 1 |
| STAD | Stomach adenocarcinoma | H371H | Silent | 1 |
| STAD | Stomach adenocarcinoma | K157N | Missense | 1 |
| STAD | Stomach adenocarcinoma | K688N | Missense | 1 |
| STAD | Stomach adenocarcinoma | M1326I | Missense | 1 |
| STAD | Stomach adenocarcinoma | M990V | Missense | 1 |
| STAD | Stomach adenocarcinoma | N886N | Silent | 1 |
| STAD | Stomach adenocarcinoma | P1429S | Missense | 1 |
| STAD | Stomach adenocarcinoma | P566L | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q222* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | R1248Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R148R | Silent | 1 |
| STAD | Stomach adenocarcinoma | R261S | Missense | 1 |
| STAD | Stomach adenocarcinoma | R289I | Missense | 1 |
| STAD | Stomach adenocarcinoma | R746C | Missense | 1 |
| STAD | Stomach adenocarcinoma | R768R | Silent | 1 |
| STAD | Stomach adenocarcinoma | R974Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | S668T | Missense | 1 |
| STAD | Stomach adenocarcinoma | T1179M | Missense | 1 |
| STAD | Stomach adenocarcinoma | T169M | Missense | 1 |
| STAD | Stomach adenocarcinoma | T729A | Missense | 1 |
| STAD | Stomach adenocarcinoma | V621M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A309V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A848T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E1104K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E51G | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E787D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F230F | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G1180D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | H490H | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I336I | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N182T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q1233H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q1297Q | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q1348* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q1369Q | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1088Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1248* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1261Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1329Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S682S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T786A | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 2.1 | 7 | 13.3 |
| BRCA | Breast invasive carcinoma | 976 | 12.8 | 2.8 | 6.7 |
| CESC | Cervical and endocervical cancers | 194 | 2.1 | 0.7 | 6.7 |
| COAD | Colon adenocarcinoma | 367 | 14.9 | 13.4 | 6.7 |
| ESCA | Esophageal carcinoma | 185 | 0 | 3.5 | 6.7 |
| GBM | Glioblastoma multiforme | 283 | 2.1 | 0.7 | 6.7 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 2.1 | 6.3 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 2.1 | 0.7 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 2.1 | 0.7 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 2.1 | 1.4 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 6.4 | 2.8 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 4.3 | 12.7 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 2.1 | 5.6 | 26.7 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 1.4 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 8.5 | 1.4 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 4.3 | 0.7 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 2.8 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 6.4 | 9.2 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 12.8 | 17.6 | 13.3 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 12.8 | 8.5 | 13.3 |