Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | Q1253Q | Silent | 4 |
| PRAD | Prostate adenocarcinoma | Q1253Q | Silent | 4 |
| ESCA | Esophageal carcinoma | Q1261Q | Silent | 3 |
| BLCA | Bladder urothelial carcinoma | F1280F | Silent | 2 |
| BLCA | Bladder urothelial carcinoma | S644* | Nonsense | 2 |
| LGG | Brain Lower Grade Glioma | Q1253Q | Silent | 2 |
| PAAD | Pancreatic adenocarcinoma | Q1253Q | Silent | 2 |
| STAD | Stomach adenocarcinoma | D718D | Silent | 2 |
| STAD | Stomach adenocarcinoma | Q1256Q | Silent | 2 |
| BLCA | Bladder urothelial carcinoma | D165N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D92N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E163K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I873M | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L1061L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | P499A | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q1141* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | Q1320* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | Q1421* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | S1291S | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | S1375C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S494L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S662C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S841T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | T103A | Missense | 1 |
| BRCA | Breast invasive carcinoma | L1060F | Missense | 1 |
| BRCA | Breast invasive carcinoma | L548W | Missense | 1 |
| BRCA | Breast invasive carcinoma | P1342S | Missense | 1 |
| BRCA | Breast invasive carcinoma | P412A | Missense | 1 |
| BRCA | Breast invasive carcinoma | Q81K | Missense | 1 |
| BRCA | Breast invasive carcinoma | S1016C | Missense | 1 |
| BRCA | Breast invasive carcinoma | S1137C | Missense | 1 |
| BRCA | Breast invasive carcinoma | S176P | Missense | 1 |
| BRCA | Breast invasive carcinoma | S819* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | V141V | Silent | 1 |
| CESC | Cervical and endocervical cancers | S671C | Missense | 1 |
| COAD | Colon adenocarcinoma | A1204V | Missense | 1 |
| COAD | Colon adenocarcinoma | A1304T | Missense | 1 |
| COAD | Colon adenocarcinoma | A70A | Silent | 1 |
| COAD | Colon adenocarcinoma | A995T | Missense | 1 |
| COAD | Colon adenocarcinoma | D566D | Silent | 1 |
| COAD | Colon adenocarcinoma | E41G | Missense | 1 |
| COAD | Colon adenocarcinoma | E704K | Missense | 1 |
| COAD | Colon adenocarcinoma | G310G | Silent | 1 |
| COAD | Colon adenocarcinoma | G326D | Missense | 1 |
| COAD | Colon adenocarcinoma | K1091T | Missense | 1 |
| COAD | Colon adenocarcinoma | M891I | Missense | 1 |
| COAD | Colon adenocarcinoma | P1198P | Silent | 1 |
| COAD | Colon adenocarcinoma | P499H | Missense | 1 |
| COAD | Colon adenocarcinoma | P499L | Missense | 1 |
| COAD | Colon adenocarcinoma | P612H | Missense | 1 |
| COAD | Colon adenocarcinoma | Q1253Q | Silent | 1 |
| COAD | Colon adenocarcinoma | Q1261Q | Silent | 1 |
| COAD | Colon adenocarcinoma | Q1263Q | Silent | 1 |
| COAD | Colon adenocarcinoma | Q1267E | Missense | 1 |
| COAD | Colon adenocarcinoma | Q1380Q | Silent | 1 |
| ESCA | Esophageal carcinoma | A1190T | Missense | 1 |
| ESCA | Esophageal carcinoma | C248F | Missense | 1 |
| ESCA | Esophageal carcinoma | K1363* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | Q1256Q | Silent | 1 |
| GBM | Glioblastoma multiforme | H592H | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D93N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K73M | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P877L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q1213Q | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R1074K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R198H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R36W | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S1413S | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S453F | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S715F | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | G1341D | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | N936K | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | Q1189E | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | R258S | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A1382V | Missense | 1 |
| LGG | Brain Lower Grade Glioma | Q1218H | Missense | 1 |
| LGG | Brain Lower Grade Glioma | Q1263Q | Silent | 1 |
| LGG | Brain Lower Grade Glioma | S413N | Missense | 1 |
| LGG | Brain Lower Grade Glioma | S842* | Nonsense | 1 |
| LGG | Brain Lower Grade Glioma | T357R | Missense | 1 |
| LGG | Brain Lower Grade Glioma | V356V | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | D1293Y | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | G1130G | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | K647R | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | M481I | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | N1043D | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | P932R | Missense | 1 |
| LUAD | Lung adenocarcinoma | A1087S | Missense | 1 |
| LUAD | Lung adenocarcinoma | A1353S | Missense | 1 |
| LUAD | Lung adenocarcinoma | A606S | Missense | 1 |
| LUAD | Lung adenocarcinoma | D93D | Silent | 1 |
| LUAD | Lung adenocarcinoma | F335L | Missense | 1 |
| LUAD | Lung adenocarcinoma | G1112V | Missense | 1 |
| LUAD | Lung adenocarcinoma | G675W | Missense | 1 |
| LUAD | Lung adenocarcinoma | I958V | Missense | 1 |
| LUAD | Lung adenocarcinoma | L688V | Missense | 1 |
| LUAD | Lung adenocarcinoma | M1395K | Missense | 1 |
| LUAD | Lung adenocarcinoma | P552L | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q1274E | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q146* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | S441S | Silent | 1 |
| LUAD | Lung adenocarcinoma | S669C | Missense | 1 |
| LUAD | Lung adenocarcinoma | T1164T | Silent | 1 |
| LUAD | Lung adenocarcinoma | T789A | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | L116R | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | L804F | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P923Q | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | Q1380H | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | D359V | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | D566Y | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | D718D | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | P1198R | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | D295V | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | S517I | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | T535T | Silent | 1 |
| PRAD | Prostate adenocarcinoma | S867G | Missense | 1 |
| READ | Rectum adenocarcinoma | D165Y | Missense | 1 |
| READ | Rectum adenocarcinoma | E209K | Missense | 1 |
| READ | Rectum adenocarcinoma | E74A | Missense | 1 |
| READ | Rectum adenocarcinoma | G1124* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | P499H | Missense | 1 |
| READ | Rectum adenocarcinoma | Q1255Q | Silent | 1 |
| READ | Rectum adenocarcinoma | Q146Q | Silent | 1 |
| READ | Rectum adenocarcinoma | R286K | Missense | 1 |
| READ | Rectum adenocarcinoma | S520R | Missense | 1 |
| SARC | Sarcoma | Q1255Q | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G692E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I480I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L473F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | N1285T | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1090L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1162P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P1310S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P656P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P868L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P868S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P915S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q1213* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q231* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | R1156Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R198C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R360G | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R487C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R849C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1216F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1337L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1343F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1343S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S536F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S635S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S916S | Silent | 1 |
| STAD | Stomach adenocarcinoma | C1424Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | G1318E | Missense | 1 |
| STAD | Stomach adenocarcinoma | H823Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | I774S | Missense | 1 |
| STAD | Stomach adenocarcinoma | L1170H | Missense | 1 |
| STAD | Stomach adenocarcinoma | L8V | Missense | 1 |
| STAD | Stomach adenocarcinoma | L961L | Silent | 1 |
| STAD | Stomach adenocarcinoma | M448T | Missense | 1 |
| STAD | Stomach adenocarcinoma | N379D | Missense | 1 |
| STAD | Stomach adenocarcinoma | N691N | Silent | 1 |
| STAD | Stomach adenocarcinoma | P850P | Silent | 1 |
| STAD | Stomach adenocarcinoma | Q119* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | Q1253Q | Silent | 1 |
| STAD | Stomach adenocarcinoma | Q1257Q | Silent | 1 |
| STAD | Stomach adenocarcinoma | Q977Q | Silent | 1 |
| STAD | Stomach adenocarcinoma | R1156Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R16* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | R964Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | S404S | Silent | 1 |
| STAD | Stomach adenocarcinoma | S494P | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | Q1257Q | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | R590R | Silent | 1 |
| THCA | Thyroid carcinoma | N358S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A1190S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G1119G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N458T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P331P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q1257Q | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q1267H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q370H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1171I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1339I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R854Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S1391N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S429R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S539F | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 12.3 | 8.2 | 35.7 |
| BRCA | Breast invasive carcinoma | 976 | 1.5 | 6.6 | 7.1 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 0.8 | 0 |
| COAD | Colon adenocarcinoma | 367 | 12.3 | 9.8 | 0 |
| ESCA | Esophageal carcinoma | 185 | 6.2 | 1.6 | 7.1 |
| GBM | Glioblastoma multiforme | 283 | 1.5 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 3.1 | 6.6 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 3.3 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 6.2 | 3.3 | 7.1 |
| LIHC | Liver hepatocellular carcinoma | 373 | 1.5 | 4.1 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 4.6 | 10.7 | 7.1 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 3.3 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 1.5 | 2.5 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 4.6 | 1.6 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 6.2 | 0.8 | 0 |
| READ | Rectum adenocarcinoma | 122 | 3.1 | 4.9 | 7.1 |
| SARC | Sarcoma | 247 | 1.5 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 9.2 | 13.9 | 14.3 |
| STAD | Stomach adenocarcinoma | 393 | 16.9 | 9 | 14.3 |
| TGCT | Testicular Germ Cell Tumors | 147 | 3.1 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0.8 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 4.6 | 8.2 | 0 |