Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | R24Q | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | E107K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E258Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E326Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E449K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E451E | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | I185I | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L147V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Y269* | Nonsense | 1 |
| CESC | Cervical and endocervical cancers | P463L | Missense | 1 |
| COAD | Colon adenocarcinoma | E415V | Missense | 1 |
| COAD | Colon adenocarcinoma | L147L | Silent | 1 |
| COAD | Colon adenocarcinoma | L147P | Missense | 1 |
| COAD | Colon adenocarcinoma | P443H | Missense | 1 |
| COAD | Colon adenocarcinoma | R24W | Missense | 1 |
| COAD | Colon adenocarcinoma | R562Q | Missense | 1 |
| COAD | Colon adenocarcinoma | S280F | Missense | 1 |
| ESCA | Esophageal carcinoma | E318D | Missense | 1 |
| ESCA | Esophageal carcinoma | F594L | Missense | 1 |
| ESCA | Esophageal carcinoma | G586G | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D557V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G195C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | I145I | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | I56V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | N319K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q291E | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R58H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V34A | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | C184Y | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | K356T | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | M187I | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | V358M | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | D419Y | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | K424K | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | V568V | Silent | 1 |
| LGG | Brain Lower Grade Glioma | I482L | Missense | 1 |
| LGG | Brain Lower Grade Glioma | K287N | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | K504K | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | R315W | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S221G | Missense | 1 |
| LUAD | Lung adenocarcinoma | C244F | Missense | 1 |
| LUAD | Lung adenocarcinoma | E318Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | K447R | Missense | 1 |
| LUAD | Lung adenocarcinoma | P463P | Silent | 1 |
| LUAD | Lung adenocarcinoma | Q40* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | S268R | Missense | 1 |
| LUAD | Lung adenocarcinoma | S57I | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | A173A | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | G251R | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A243A | Silent | 1 |
| PRAD | Prostate adenocarcinoma | R315Q | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R315R | Silent | 1 |
| PRAD | Prostate adenocarcinoma | S267* | Nonsense | 1 |
| PRAD | Prostate adenocarcinoma | S311F | Missense | 1 |
| READ | Rectum adenocarcinoma | R562Q | Missense | 1 |
| SARC | Sarcoma | L498F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G155R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I219M | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q333* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | A30V | Missense | 1 |
| STAD | Stomach adenocarcinoma | H394H | Silent | 1 |
| STAD | Stomach adenocarcinoma | K263E | Missense | 1 |
| STAD | Stomach adenocarcinoma | L330R | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q117* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | R24W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R58R | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | K545N | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | Q392H | Missense | 1 |
| THCA | Thyroid carcinoma | S12R | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A115T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K263G | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K475T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R315Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R562Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R609Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S530S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V403M | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 13.3 | 8.6 | 20 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 0 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 1.7 | 0 |
| COAD | Colon adenocarcinoma | 367 | 6.7 | 13.8 | 0 |
| ESCA | Esophageal carcinoma | 185 | 6.7 | 3.4 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 6.7 | 12.1 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 6.9 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 13.3 | 1.7 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 3.4 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 6.7 | 3.4 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 6.7 | 8.6 | 20 |
| LUSC | Lung squamous cell carcinoma | 177 | 6.7 | 0 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 1.7 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 13.3 | 3.4 | 20 |
| READ | Rectum adenocarcinoma | 122 | 0 | 1.7 | 0 |
| SARC | Sarcoma | 247 | 0 | 1.7 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 0 | 3.4 | 20 |
| STAD | Stomach adenocarcinoma | 393 | 13.3 | 6.9 | 20 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 3.4 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 1.7 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 6.7 | 12.1 | 0 |