Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | T705A | Missense | 3 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E369D | Missense | 3 |
| BLCA | Bladder urothelial carcinoma | D767H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D930N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E495K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L200L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | N512N | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | S916C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | T388I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V242V | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | V714V | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | W804C | Missense | 1 |
| BRCA | Breast invasive carcinoma | C270C | Silent | 1 |
| BRCA | Breast invasive carcinoma | D194N | Missense | 1 |
| BRCA | Breast invasive carcinoma | G801V | Missense | 1 |
| BRCA | Breast invasive carcinoma | G814R | Missense | 1 |
| BRCA | Breast invasive carcinoma | P803T | Missense | 1 |
| CESC | Cervical and endocervical cancers | D923N | Missense | 1 |
| COAD | Colon adenocarcinoma | E488G | Missense | 1 |
| COAD | Colon adenocarcinoma | K662E | Missense | 1 |
| COAD | Colon adenocarcinoma | P590P | Silent | 1 |
| COAD | Colon adenocarcinoma | P666P | Silent | 1 |
| COAD | Colon adenocarcinoma | P774S | Missense | 1 |
| COAD | Colon adenocarcinoma | R793G | Missense | 1 |
| COAD | Colon adenocarcinoma | R900L | Missense | 1 |
| COAD | Colon adenocarcinoma | T705S | Missense | 1 |
| COAD | Colon adenocarcinoma | W804* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | Y704C | Missense | 1 |
| ESCA | Esophageal carcinoma | D53Y | Missense | 1 |
| ESCA | Esophageal carcinoma | R447Q | Missense | 1 |
| ESCA | Esophageal carcinoma | S763S | Silent | 1 |
| GBM | Glioblastoma multiforme | D434V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E573K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | M667I | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S208S | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T123T | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V459L | Missense | 1 |
| LAML | Acute Myeloid Leukemia | K584E | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A450D | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A797T | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R757C | Missense | 1 |
| LGG | Brain Lower Grade Glioma | S381P | Missense | 1 |
| LGG | Brain Lower Grade Glioma | T705I | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | G568C | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | K103T | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | K85R | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | L155I | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | N120K | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | V206A | Missense | 1 |
| LUAD | Lung adenocarcinoma | A694S | Missense | 1 |
| LUAD | Lung adenocarcinoma | D935H | Missense | 1 |
| LUAD | Lung adenocarcinoma | E212K | Missense | 1 |
| LUAD | Lung adenocarcinoma | N136D | Missense | 1 |
| LUAD | Lung adenocarcinoma | W939S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | D53H | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G262V | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | M493I | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R80G | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | T705T | Silent | 1 |
| PCPG | Pheochromocytoma and Paraganglioma | E309Q | Missense | 1 |
| READ | Rectum adenocarcinoma | F322L | Missense | 1 |
| READ | Rectum adenocarcinoma | S595Y | Missense | 1 |
| READ | Rectum adenocarcinoma | T705I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I749I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | K584N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L811L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | N136S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | N625D | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P298L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P385S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | V49A | Missense | 1 |
| STAD | Stomach adenocarcinoma | D53H | Missense | 1 |
| STAD | Stomach adenocarcinoma | D930H | Missense | 1 |
| STAD | Stomach adenocarcinoma | E204K | Missense | 1 |
| STAD | Stomach adenocarcinoma | F853L | Missense | 1 |
| STAD | Stomach adenocarcinoma | G859A | Missense | 1 |
| STAD | Stomach adenocarcinoma | G912R | Missense | 1 |
| STAD | Stomach adenocarcinoma | K353R | Missense | 1 |
| STAD | Stomach adenocarcinoma | P534T | Missense | 1 |
| STAD | Stomach adenocarcinoma | R333* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | T148A | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | G912* | Nonsense | 1 |
| TGCT | Testicular Germ Cell Tumors | K585R | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | Q26E | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D483Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D557G | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D92D | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E115K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E215G | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E544* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F707F | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F738L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K253T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K542T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L593L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R333L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R757C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S343S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V34A | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y14F | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 23.5 | 7.2 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 5.9 | 4.8 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 1.2 | 0 |
| COAD | Colon adenocarcinoma | 367 | 11.8 | 12 | 25 |
| ESCA | Esophageal carcinoma | 185 | 5.9 | 2.4 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 1.2 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 11.8 | 3.6 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 1.2 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 6 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 7.2 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 0 | 6 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 4.8 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 5.9 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 1.2 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 3.6 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 11.8 | 7.2 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 0 | 10.8 | 25 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 2.4 | 25 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 23.5 | 16.9 | 25 |