Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| KIRC | Kidney renal clear cell carcinoma | R1010* | Nonsense | 3 |
| COAD | Colon adenocarcinoma | R58* | Nonsense | 2 |
| KIRC | Kidney renal clear cell carcinoma | R1052* | Nonsense | 2 |
| KIRC | Kidney renal clear cell carcinoma | R1185* | Nonsense | 2 |
| KIRC | Kidney renal clear cell carcinoma | R58* | Nonsense | 2 |
| KIRC | Kidney renal clear cell carcinoma | R850* | Nonsense | 2 |
| LIHC | Liver hepatocellular carcinoma | R472* | Nonsense | 2 |
| LIHC | Liver hepatocellular carcinoma | V1527L | Missense | 2 |
| LUAD | Lung adenocarcinoma | S941* | Nonsense | 2 |
| BLCA | Bladder urothelial carcinoma | D1286N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D1325N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E1049K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E1132K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E1645* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | E583K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E767Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E846K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E905Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E990K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I1309T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K1373N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L1653L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L182F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | M1383I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | M499I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | N1262D | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P1496L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q153Q | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | Q779E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R1096C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R1173C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R876C | Missense | 1 |
| BRCA | Breast invasive carcinoma | E1014Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | G1554R | Missense | 1 |
| BRCA | Breast invasive carcinoma | L886V | Missense | 1 |
| BRCA | Breast invasive carcinoma | M1539I | Missense | 1 |
| BRCA | Breast invasive carcinoma | M586I | Missense | 1 |
| BRCA | Breast invasive carcinoma | N739N | Silent | 1 |
| BRCA | Breast invasive carcinoma | R394S | Missense | 1 |
| BRCA | Breast invasive carcinoma | V1037V | Silent | 1 |
| CESC | Cervical and endocervical cancers | I376M | Missense | 1 |
| CESC | Cervical and endocervical cancers | I575N | Missense | 1 |
| CESC | Cervical and endocervical cancers | Q388* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | A192T | Missense | 1 |
| COAD | Colon adenocarcinoma | D1637D | Silent | 1 |
| COAD | Colon adenocarcinoma | E1214E | Silent | 1 |
| COAD | Colon adenocarcinoma | E564* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | F1012V | Missense | 1 |
| COAD | Colon adenocarcinoma | F1277L | Missense | 1 |
| COAD | Colon adenocarcinoma | G1187R | Missense | 1 |
| COAD | Colon adenocarcinoma | K277* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | P1524P | Silent | 1 |
| COAD | Colon adenocarcinoma | R298* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | R836W | Missense | 1 |
| COAD | Colon adenocarcinoma | S32R | Missense | 1 |
| COAD | Colon adenocarcinoma | T821K | Missense | 1 |
| ESCA | Esophageal carcinoma | A362D | Missense | 1 |
| ESCA | Esophageal carcinoma | A459V | Missense | 1 |
| ESCA | Esophageal carcinoma | D446H | Missense | 1 |
| ESCA | Esophageal carcinoma | M586I | Missense | 1 |
| ESCA | Esophageal carcinoma | N121K | Missense | 1 |
| ESCA | Esophageal carcinoma | P427P | Silent | 1 |
| ESCA | Esophageal carcinoma | R522* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | R58* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | R58R | Silent | 1 |
| GBM | Glioblastoma multiforme | E1248G | Missense | 1 |
| GBM | Glioblastoma multiforme | R1411C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E105Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E356* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L1304F | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L68F | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L886L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | N528I | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q1298Q | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R679H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R760H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R835C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R921* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S343L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S605F | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S941* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | A928A | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | C1233W | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E1016* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E1132* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E1137* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E1287D | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E160* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E368* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E457* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E602* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E846* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E860K | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E981* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | G626V | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | I252R | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | I709T | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | K243* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | K485* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | K96* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | L1611P | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | L614V | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | L618H | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | L618L | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | L886R | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | M523R | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | M586K | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | M586T | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | N528I | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | N601K | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | P1048L | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | P1048R | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | P42L | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | Q1298* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | Q1570* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | Q188* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | Q209* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | Q422* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | Q440* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | Q779* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | Q869* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | R1670P | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | R690* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | R710* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | R798* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | R876L | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | R921* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | S10T | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | S295* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | S371* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | S502* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | S788* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | S859* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | T1202K | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | W1417G | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | Y1261* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | Y1428* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | Y580C | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | Y666* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | Y718C | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | A890E | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | P1520T | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | R710* | Nonsense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | Y1575* | Nonsense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | Y331C | Missense | 1 |
| LGG | Brain Lower Grade Glioma | F280V | Missense | 1 |
| LGG | Brain Lower Grade Glioma | P1360P | Silent | 1 |
| LGG | Brain Lower Grade Glioma | P556S | Missense | 1 |
| LGG | Brain Lower Grade Glioma | P741P | Silent | 1 |
| LGG | Brain Lower Grade Glioma | Q660H | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R1260C | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R921* | Nonsense | 1 |
| LGG | Brain Lower Grade Glioma | S788S | Silent | 1 |
| LGG | Brain Lower Grade Glioma | V1040V | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | E1287K | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S1377A | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | T1247I | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | V755V | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | Y1610H | Missense | 1 |
| LUAD | Lung adenocarcinoma | E981Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | K623R | Missense | 1 |
| LUAD | Lung adenocarcinoma | M731K | Missense | 1 |
| LUAD | Lung adenocarcinoma | N739S | Missense | 1 |
| LUAD | Lung adenocarcinoma | R522L | Missense | 1 |
| LUAD | Lung adenocarcinoma | S3S | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | D823H | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E184D | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E226Q | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | F456S | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | F594F | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | I245F | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R1000G | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | I193I | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | K231R | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | Y963* | Nonsense | 1 |
| PAAD | Pancreatic adenocarcinoma | E572* | Nonsense | 1 |
| PAAD | Pancreatic adenocarcinoma | L1274V | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R1096C | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R540T | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R876C | Missense | 1 |
| PRAD | Prostate adenocarcinoma | G17R | Missense | 1 |
| PRAD | Prostate adenocarcinoma | I252I | Silent | 1 |
| PRAD | Prostate adenocarcinoma | P427L | Missense | 1 |
| PRAD | Prostate adenocarcinoma | V152F | Missense | 1 |
| PRAD | Prostate adenocarcinoma | Y1290Y | Silent | 1 |
| READ | Rectum adenocarcinoma | E1318K | Missense | 1 |
| READ | Rectum adenocarcinoma | Q99Q | Silent | 1 |
| READ | Rectum adenocarcinoma | T737T | Silent | 1 |
| SARC | Sarcoma | L1388L | Silent | 1 |
| SARC | Sarcoma | S743T | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D674D | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | D962D | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | K1270Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | K1299K | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | K702T | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | K717* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | L1631L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L1672M | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L361* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | L804* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | N528S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1225S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P313S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R1062Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R1185* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | R710* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | S378S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S505F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | V1086V | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | W1183* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | Y1063* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | A192V | Missense | 1 |
| STAD | Stomach adenocarcinoma | D115V | Missense | 1 |
| STAD | Stomach adenocarcinoma | E1054V | Missense | 1 |
| STAD | Stomach adenocarcinoma | F1051V | Missense | 1 |
| STAD | Stomach adenocarcinoma | F116F | Silent | 1 |
| STAD | Stomach adenocarcinoma | G1376G | Silent | 1 |
| STAD | Stomach adenocarcinoma | K61T | Missense | 1 |
| STAD | Stomach adenocarcinoma | M724T | Missense | 1 |
| STAD | Stomach adenocarcinoma | N121Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q719R | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1000Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1185* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | R1379W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R576H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R78* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | V964I | Missense | 1 |
| STAD | Stomach adenocarcinoma | Y1290F | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | S303S | Silent | 1 |
| THYM | Thymoma | N1126S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D159D | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D20G | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F1316C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F871L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K1034* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P427S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1088Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1185* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R921* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S275* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T821A | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 5.6 | 14.5 | 1.3 |
| BRCA | Breast invasive carcinoma | 976 | 5.6 | 4.3 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 1.4 | 1.3 |
| COAD | Colon adenocarcinoma | 367 | 8.3 | 5.1 | 6.5 |
| ESCA | Esophageal carcinoma | 185 | 5.6 | 3.6 | 2.6 |
| GBM | Glioblastoma multiforme | 283 | 0 | 1.4 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 5.6 | 6.5 | 3.9 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 5.6 | 18.1 | 55.8 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 2.2 | 2.6 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 11.1 | 2.9 | 1.3 |
| LIHC | Liver hepatocellular carcinoma | 373 | 2.8 | 4.3 | 2.6 |
| LUAD | Lung adenocarcinoma | 533 | 2.8 | 3.6 | 2.6 |
| LUSC | Lung squamous cell carcinoma | 177 | 2.8 | 4.3 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 2.8 | 0.7 | 1.3 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 2.9 | 1.3 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 5.6 | 2.2 | 0 |
| READ | Rectum adenocarcinoma | 122 | 5.6 | 0.7 | 0 |
| SARC | Sarcoma | 247 | 2.8 | 0.7 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 16.7 | 5.8 | 9.1 |
| STAD | Stomach adenocarcinoma | 393 | 5.6 | 9.4 | 2.6 |
| TGCT | Testicular Germ Cell Tumors | 147 | 2.8 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0.7 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 2.8 | 4.3 | 5.2 |