Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | S613P | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | E775E | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | I986M | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S115R | Missense | 1 |
| BRCA | Breast invasive carcinoma | A418A | Silent | 1 |
| BRCA | Breast invasive carcinoma | S22C | Missense | 1 |
| CESC | Cervical and endocervical cancers | C823C | Silent | 1 |
| CESC | Cervical and endocervical cancers | E978Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | R867H | Missense | 1 |
| COAD | Colon adenocarcinoma | A111T | Missense | 1 |
| COAD | Colon adenocarcinoma | C800C | Silent | 1 |
| COAD | Colon adenocarcinoma | C823C | Silent | 1 |
| COAD | Colon adenocarcinoma | E879* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | L133L | Silent | 1 |
| COAD | Colon adenocarcinoma | L837P | Missense | 1 |
| COAD | Colon adenocarcinoma | N143D | Missense | 1 |
| COAD | Colon adenocarcinoma | R152W | Missense | 1 |
| COAD | Colon adenocarcinoma | R355Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R45W | Missense | 1 |
| COAD | Colon adenocarcinoma | R854H | Missense | 1 |
| COAD | Colon adenocarcinoma | R859H | Missense | 1 |
| COAD | Colon adenocarcinoma | R860H | Missense | 1 |
| COAD | Colon adenocarcinoma | S5S | Silent | 1 |
| COAD | Colon adenocarcinoma | S761P | Missense | 1 |
| ESCA | Esophageal carcinoma | A424V | Missense | 1 |
| ESCA | Esophageal carcinoma | A809T | Missense | 1 |
| ESCA | Esophageal carcinoma | G720A | Missense | 1 |
| ESCA | Esophageal carcinoma | R82R | Silent | 1 |
| GBM | Glioblastoma multiforme | V729M | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A360A | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K993M | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R860C | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A215T | Missense | 1 |
| LGG | Brain Lower Grade Glioma | H736R | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R836R | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | S786S | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | T356K | Missense | 1 |
| LUAD | Lung adenocarcinoma | A125P | Missense | 1 |
| LUAD | Lung adenocarcinoma | P631A | Missense | 1 |
| LUAD | Lung adenocarcinoma | P770P | Silent | 1 |
| LUAD | Lung adenocarcinoma | Y806F | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P361P | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | A101T | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R852R | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | R854H | Missense | 1 |
| PRAD | Prostate adenocarcinoma | M719I | Missense | 1 |
| PRAD | Prostate adenocarcinoma | S653C | Missense | 1 |
| SARC | Sarcoma | P451Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G302G | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | I395N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L142L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L40L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P660S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R152G | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R167W | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | V652V | Silent | 1 |
| STAD | Stomach adenocarcinoma | L208S | Missense | 1 |
| STAD | Stomach adenocarcinoma | R306R | Silent | 1 |
| STAD | Stomach adenocarcinoma | R852R | Silent | 1 |
| STAD | Stomach adenocarcinoma | S15R | Missense | 1 |
| STAD | Stomach adenocarcinoma | Y802H | Missense | 1 |
| STAD | Stomach adenocarcinoma | Y806N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A795A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I870M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P461P | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 4.5 | 4.7 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 4.5 | 2.3 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 4.5 | 4.7 | 0 |
| COAD | Colon adenocarcinoma | 367 | 18.2 | 27.9 | 100 |
| ESCA | Esophageal carcinoma | 185 | 4.5 | 7 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 2.3 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 4.5 | 4.7 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 4.5 | 4.7 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 4.5 | 2.3 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 4.5 | 7 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 4.5 | 0 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 2.3 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 4.5 | 2.3 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 4.7 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 0 | 0 |
| SARC | Sarcoma | 247 | 0 | 2.3 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 18.2 | 9.3 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 9.1 | 9.3 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 9.1 | 2.3 | 0 |