Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | E797Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R699Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | A92A | Silent | 1 |
| BRCA | Breast invasive carcinoma | E643A | Missense | 1 |
| BRCA | Breast invasive carcinoma | R699W | Missense | 1 |
| BRCA | Breast invasive carcinoma | S621L | Missense | 1 |
| BRCA | Breast invasive carcinoma | V204L | Missense | 1 |
| BRCA | Breast invasive carcinoma | V671L | Missense | 1 |
| CESC | Cervical and endocervical cancers | A251A | Silent | 1 |
| CESC | Cervical and endocervical cancers | I60M | Missense | 1 |
| CESC | Cervical and endocervical cancers | L771R | Missense | 1 |
| CESC | Cervical and endocervical cancers | Q77H | Missense | 1 |
| CESC | Cervical and endocervical cancers | R228* | Nonsense | 1 |
| CESC | Cervical and endocervical cancers | R39C | Missense | 1 |
| CESC | Cervical and endocervical cancers | T537N | Missense | 1 |
| COAD | Colon adenocarcinoma | A81T | Missense | 1 |
| COAD | Colon adenocarcinoma | G257G | Silent | 1 |
| COAD | Colon adenocarcinoma | G306D | Missense | 1 |
| COAD | Colon adenocarcinoma | G418G | Silent | 1 |
| COAD | Colon adenocarcinoma | H320Y | Missense | 1 |
| COAD | Colon adenocarcinoma | K710N | Missense | 1 |
| COAD | Colon adenocarcinoma | L750L | Silent | 1 |
| COAD | Colon adenocarcinoma | P132P | Silent | 1 |
| COAD | Colon adenocarcinoma | P514S | Missense | 1 |
| COAD | Colon adenocarcinoma | Q466H | Missense | 1 |
| COAD | Colon adenocarcinoma | R39C | Missense | 1 |
| COAD | Colon adenocarcinoma | R656C | Missense | 1 |
| COAD | Colon adenocarcinoma | R777W | Missense | 1 |
| COAD | Colon adenocarcinoma | S21S | Silent | 1 |
| COAD | Colon adenocarcinoma | S723L | Missense | 1 |
| COAD | Colon adenocarcinoma | T759H | Missense | 1 |
| COAD | Colon adenocarcinoma | V720M | Missense | 1 |
| ESCA | Esophageal carcinoma | A72T | Missense | 1 |
| ESCA | Esophageal carcinoma | R656H | Missense | 1 |
| ESCA | Esophageal carcinoma | S21N | Missense | 1 |
| ESCA | Esophageal carcinoma | T717I | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A234V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L262L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P261L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q494Q | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q76Q | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S121G | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S37G | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V677M | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Y849C | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | C665Y | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | P406Q | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | C29* | Nonsense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | I821M | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A582V | Missense | 1 |
| LGG | Brain Lower Grade Glioma | T90T | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | A165A | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | H775R | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | I323T | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S311R | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | T529T | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | T731T | Silent | 1 |
| LUAD | Lung adenocarcinoma | F448L | Missense | 1 |
| LUAD | Lung adenocarcinoma | L846L | Silent | 1 |
| LUAD | Lung adenocarcinoma | N297S | Missense | 1 |
| LUAD | Lung adenocarcinoma | N557K | Missense | 1 |
| LUAD | Lung adenocarcinoma | V314V | Silent | 1 |
| LUAD | Lung adenocarcinoma | Y746Y | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | A129A | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | F448L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G823R | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | D822E | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | L750F | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | L644L | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | P752H | Missense | 1 |
| PRAD | Prostate adenocarcinoma | G549S | Missense | 1 |
| PRAD | Prostate adenocarcinoma | Y627D | Missense | 1 |
| READ | Rectum adenocarcinoma | S11Y | Missense | 1 |
| READ | Rectum adenocarcinoma | S143P | Missense | 1 |
| SARC | Sarcoma | T508T | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | F585F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | F605F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L644R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P637L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P637S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T56T | Silent | 1 |
| STAD | Stomach adenocarcinoma | A129V | Missense | 1 |
| STAD | Stomach adenocarcinoma | E574D | Missense | 1 |
| STAD | Stomach adenocarcinoma | G172G | Silent | 1 |
| STAD | Stomach adenocarcinoma | L188L | Silent | 1 |
| STAD | Stomach adenocarcinoma | P361Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | P514P | Silent | 1 |
| STAD | Stomach adenocarcinoma | R39H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R54R | Silent | 1 |
| STAD | Stomach adenocarcinoma | R697H | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | Q457K | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | R656R | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | V300V | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A453T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A693V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I573I | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I821I | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L834P | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q67Q | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R699W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R817C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T70M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V57M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y79H | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 2.9 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 3.1 | 7.1 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 3.1 | 7.1 | 50 |
| COAD | Colon adenocarcinoma | 367 | 15.6 | 17.1 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 5.7 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 9.4 | 8.6 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 2.9 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 1.4 | 50 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 3.1 | 1.4 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 9.4 | 4.3 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 9.4 | 4.3 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 3.1 | 2.9 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 2.9 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 3.1 | 1.4 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 2.9 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 2.9 | 0 |
| SARC | Sarcoma | 247 | 3.1 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 9.4 | 4.3 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 12.5 | 7.1 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 6.2 | 1.4 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 9.4 | 11.4 | 0 |