Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | R124R | Silent | 6 |
| LIHC | Liver hepatocellular carcinoma | M448V | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | L277L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L74L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | S323F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Y370C | Missense | 1 |
| COAD | Colon adenocarcinoma | A203A | Silent | 1 |
| COAD | Colon adenocarcinoma | L398L | Silent | 1 |
| COAD | Colon adenocarcinoma | R142H | Missense | 1 |
| COAD | Colon adenocarcinoma | R170H | Missense | 1 |
| COAD | Colon adenocarcinoma | Y276H | Missense | 1 |
| ESCA | Esophageal carcinoma | L123L | Silent | 1 |
| ESCA | Esophageal carcinoma | R247L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E305K | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | D298E | Missense | 1 |
| LGG | Brain Lower Grade Glioma | Y276C | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | E273* | Nonsense | 1 |
| LIHC | Liver hepatocellular carcinoma | Q171* | Nonsense | 1 |
| LIHC | Liver hepatocellular carcinoma | S301S | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | V250V | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | F461F | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | P244P | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | P278P | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | Y199D | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | K493T | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | Y88H | Missense | 1 |
| PRAD | Prostate adenocarcinoma | L257V | Missense | 1 |
| PRAD | Prostate adenocarcinoma | Q441* | Nonsense | 1 |
| READ | Rectum adenocarcinoma | D414G | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P358S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S339F | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q91R | Missense | 1 |
| THYM | Thymoma | R113Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E92* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R308Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R491R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S339Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V100V | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 11.1 | 9.1 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 0 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 0 | 0 |
| COAD | Colon adenocarcinoma | 367 | 44.4 | 13.6 | 0 |
| ESCA | Esophageal carcinoma | 185 | 5.6 | 4.5 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 4.5 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 4.5 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 4.5 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 11.1 | 9.1 | 50 |
| LUAD | Lung adenocarcinoma | 533 | 0 | 0 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 16.7 | 4.5 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 9.1 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 4.5 | 25 |
| READ | Rectum adenocarcinoma | 122 | 0 | 4.5 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 0 | 9.1 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 0 | 4.5 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 4.5 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 11.1 | 9.1 | 25 |