Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | S177W | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | T292T | Silent | 1 |
| BRCA | Breast invasive carcinoma | K20T | Missense | 1 |
| BRCA | Breast invasive carcinoma | T254P | Missense | 1 |
| CESC | Cervical and endocervical cancers | H257Y | Missense | 1 |
| CESC | Cervical and endocervical cancers | P164S | Missense | 1 |
| COAD | Colon adenocarcinoma | C277Y | Missense | 1 |
| COAD | Colon adenocarcinoma | R22H | Missense | 1 |
| COAD | Colon adenocarcinoma | R244H | Missense | 1 |
| COAD | Colon adenocarcinoma | S259S | Silent | 1 |
| COAD | Colon adenocarcinoma | V233M | Missense | 1 |
| ESCA | Esophageal carcinoma | R278W | Missense | 1 |
| ESCA | Esophageal carcinoma | S104G | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S169A | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S173F | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S173S | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | A37V | Missense | 1 |
| LGG | Brain Lower Grade Glioma | S280S | Silent | 1 |
| LGG | Brain Lower Grade Glioma | W230* | Nonsense | 1 |
| LIHC | Liver hepatocellular carcinoma | N288S | Missense | 1 |
| LUAD | Lung adenocarcinoma | S178I | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | P164P | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | R210L | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A242V | Missense | 1 |
| PRAD | Prostate adenocarcinoma | G138A | Missense | 1 |
| READ | Rectum adenocarcinoma | D68D | Silent | 1 |
| SARC | Sarcoma | D174N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I200I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P176L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R210* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | R278Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | D227D | Silent | 1 |
| STAD | Stomach adenocarcinoma | R210Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E191* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E48D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K102N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R125S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R210* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S154N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T113M | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 12.5 | 3.6 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 7.1 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 7.1 | 0 |
| COAD | Colon adenocarcinoma | 367 | 12.5 | 14.3 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 7.1 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 12.5 | 7.1 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 3.6 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 12.5 | 0 | 25 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 3.6 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 0 | 3.6 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 12.5 | 3.6 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 3.6 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 3.6 | 0 |
| READ | Rectum adenocarcinoma | 122 | 12.5 | 0 | 0 |
| SARC | Sarcoma | 247 | 0 | 3.6 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 12.5 | 7.1 | 25 |
| STAD | Stomach adenocarcinoma | 393 | 12.5 | 3.6 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 0 | 17.9 | 50 |