Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | E553E | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | I253M | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R209W | Missense | 1 |
| BRCA | Breast invasive carcinoma | L535L | Silent | 1 |
| BRCA | Breast invasive carcinoma | P344P | Silent | 1 |
| BRCA | Breast invasive carcinoma | R215P | Missense | 1 |
| BRCA | Breast invasive carcinoma | S187W | Missense | 1 |
| BRCA | Breast invasive carcinoma | V261G | Missense | 1 |
| COAD | Colon adenocarcinoma | A151T | Missense | 1 |
| COAD | Colon adenocarcinoma | E515K | Missense | 1 |
| COAD | Colon adenocarcinoma | K23K | Silent | 1 |
| COAD | Colon adenocarcinoma | S38P | Missense | 1 |
| ESCA | Esophageal carcinoma | R155R | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E222K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P109P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R489Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S177A | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | P499A | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | R497H | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | P8P | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | Y197C | Missense | 1 |
| LUAD | Lung adenocarcinoma | E429K | Missense | 1 |
| LUAD | Lung adenocarcinoma | E573D | Missense | 1 |
| LUAD | Lung adenocarcinoma | L258Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | L317L | Silent | 1 |
| LUAD | Lung adenocarcinoma | Q274L | Missense | 1 |
| LUAD | Lung adenocarcinoma | S107L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | A151V | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | L20L | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | E96K | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | H417R | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | C48C | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | C498C | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P203P | Silent | 1 |
| STAD | Stomach adenocarcinoma | E527K | Missense | 1 |
| STAD | Stomach adenocarcinoma | L57L | Silent | 1 |
| STAD | Stomach adenocarcinoma | R369H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R548W | Missense | 1 |
| STAD | Stomach adenocarcinoma | S366F | Missense | 1 |
| STAD | Stomach adenocarcinoma | S531S | Silent | 1 |
| STAD | Stomach adenocarcinoma | V46A | Missense | 1 |
| STAD | Stomach adenocarcinoma | V509D | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | C198C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E329D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E75K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L399V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L485M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R209W | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 6.7 | 6.1 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 13.3 | 9.1 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 0 | 0 |
| COAD | Colon adenocarcinoma | 367 | 6.7 | 9.1 | 0 |
| ESCA | Esophageal carcinoma | 185 | 6.7 | 0 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 6.7 | 9.1 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 3 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 3 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 6.7 | 3 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 6.7 | 15.2 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 6.7 | 3 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 6.1 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 6.7 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 0 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 13.3 | 0 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 13.3 | 18.2 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 6.7 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 0 | 15.2 | 0 |