Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| STAD | Stomach adenocarcinoma | P500T | Missense | 2 |
| STAD | Stomach adenocarcinoma | T493A | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | E590D | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | F205F | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | G836C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | H260Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L88L | Silent | 1 |
| BRCA | Breast invasive carcinoma | A25T | Missense | 1 |
| BRCA | Breast invasive carcinoma | L1086L | Silent | 1 |
| BRCA | Breast invasive carcinoma | Q1080H | Missense | 1 |
| BRCA | Breast invasive carcinoma | R592* | Nonsense | 1 |
| CESC | Cervical and endocervical cancers | D24H | Missense | 1 |
| CESC | Cervical and endocervical cancers | E417Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | I90I | Silent | 1 |
| COAD | Colon adenocarcinoma | A628V | Missense | 1 |
| COAD | Colon adenocarcinoma | A761T | Missense | 1 |
| COAD | Colon adenocarcinoma | A820V | Missense | 1 |
| COAD | Colon adenocarcinoma | C240C | Silent | 1 |
| COAD | Colon adenocarcinoma | F332F | Silent | 1 |
| COAD | Colon adenocarcinoma | F363L | Missense | 1 |
| COAD | Colon adenocarcinoma | K634T | Missense | 1 |
| COAD | Colon adenocarcinoma | N191N | Silent | 1 |
| COAD | Colon adenocarcinoma | P451P | Silent | 1 |
| COAD | Colon adenocarcinoma | P473P | Silent | 1 |
| COAD | Colon adenocarcinoma | P508P | Silent | 1 |
| COAD | Colon adenocarcinoma | P983P | Silent | 1 |
| COAD | Colon adenocarcinoma | R592* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | R922C | Missense | 1 |
| COAD | Colon adenocarcinoma | R94Q | Missense | 1 |
| COAD | Colon adenocarcinoma | S183N | Missense | 1 |
| COAD | Colon adenocarcinoma | S275L | Missense | 1 |
| COAD | Colon adenocarcinoma | T1040A | Missense | 1 |
| COAD | Colon adenocarcinoma | T520M | Missense | 1 |
| COAD | Colon adenocarcinoma | V449I | Missense | 1 |
| ESCA | Esophageal carcinoma | G388W | Missense | 1 |
| ESCA | Esophageal carcinoma | K389N | Missense | 1 |
| ESCA | Esophageal carcinoma | P500T | Missense | 1 |
| ESCA | Esophageal carcinoma | P512H | Missense | 1 |
| ESCA | Esophageal carcinoma | P692L | Missense | 1 |
| ESCA | Esophageal carcinoma | P700P | Silent | 1 |
| ESCA | Esophageal carcinoma | P747S | Missense | 1 |
| ESCA | Esophageal carcinoma | S997T | Missense | 1 |
| ESCA | Esophageal carcinoma | T493A | Missense | 1 |
| ESCA | Esophageal carcinoma | T716M | Missense | 1 |
| GBM | Glioblastoma multiforme | P140P | Silent | 1 |
| GBM | Glioblastoma multiforme | P423S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A380A | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D808N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E22G | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E367K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | F332F | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K894N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V146I | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | I271L | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | L422L | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | L811L | Silent | 1 |
| LGG | Brain Lower Grade Glioma | C26C | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | G684C | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | L811L | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | N780S | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | P983P | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | S288C | Missense | 1 |
| LUAD | Lung adenocarcinoma | A1037S | Missense | 1 |
| LUAD | Lung adenocarcinoma | C53W | Missense | 1 |
| LUAD | Lung adenocarcinoma | D675E | Missense | 1 |
| LUAD | Lung adenocarcinoma | E443* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | E54* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | E923D | Missense | 1 |
| LUAD | Lung adenocarcinoma | G134G | Silent | 1 |
| LUAD | Lung adenocarcinoma | G134V | Missense | 1 |
| LUAD | Lung adenocarcinoma | L650L | Silent | 1 |
| LUAD | Lung adenocarcinoma | L768R | Missense | 1 |
| LUAD | Lung adenocarcinoma | L866L | Silent | 1 |
| LUAD | Lung adenocarcinoma | Q1080Q | Silent | 1 |
| LUAD | Lung adenocarcinoma | R674Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | S809Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | T716T | Silent | 1 |
| LUAD | Lung adenocarcinoma | T963T | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | E102K | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | Q362E | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | V104L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | V910V | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | W284L | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | P1013L | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | T312T | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | E41E | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | F366Y | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | K602R | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | S800S | Silent | 1 |
| PRAD | Prostate adenocarcinoma | A1078T | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A369V | Missense | 1 |
| PRAD | Prostate adenocarcinoma | G388A | Missense | 1 |
| READ | Rectum adenocarcinoma | A849T | Missense | 1 |
| READ | Rectum adenocarcinoma | V854V | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | E667E | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | F637L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L572L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P130S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P316L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P364P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P392P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P721L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P903L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P903S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R107S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S474F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S573N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S760L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S800F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S891S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | V753V | Silent | 1 |
| STAD | Stomach adenocarcinoma | A935V | Missense | 1 |
| STAD | Stomach adenocarcinoma | D148D | Silent | 1 |
| STAD | Stomach adenocarcinoma | D675D | Silent | 1 |
| STAD | Stomach adenocarcinoma | D900D | Silent | 1 |
| STAD | Stomach adenocarcinoma | F205F | Silent | 1 |
| STAD | Stomach adenocarcinoma | G775G | Silent | 1 |
| STAD | Stomach adenocarcinoma | I930I | Silent | 1 |
| STAD | Stomach adenocarcinoma | M801T | Missense | 1 |
| STAD | Stomach adenocarcinoma | P273T | Missense | 1 |
| STAD | Stomach adenocarcinoma | P480P | Silent | 1 |
| STAD | Stomach adenocarcinoma | P700L | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1070C | Missense | 1 |
| STAD | Stomach adenocarcinoma | R896M | Missense | 1 |
| STAD | Stomach adenocarcinoma | S625S | Silent | 1 |
| STAD | Stomach adenocarcinoma | T455A | Missense | 1 |
| STAD | Stomach adenocarcinoma | V680M | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | K564R | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | L941F | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | R107H | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | T143T | Silent | 1 |
| THYM | Thymoma | S823S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A661T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C240C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D855N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D872N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E150K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E549K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F659F | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F889F | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K213N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K894N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L934L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R283H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R694W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S183S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V456V | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 3.8 | 3.3 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 1.9 | 2.2 | 25 |
| CESC | Cervical and endocervical cancers | 194 | 1.9 | 2.2 | 0 |
| COAD | Colon adenocarcinoma | 367 | 13.2 | 13 | 25 |
| ESCA | Esophageal carcinoma | 185 | 1.9 | 9.8 | 0 |
| GBM | Glioblastoma multiforme | 283 | 1.9 | 1.1 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 3.8 | 5.4 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 3.8 | 1.1 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 1.9 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 3.8 | 3.3 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 11.3 | 8.7 | 50 |
| LUSC | Lung squamous cell carcinoma | 177 | 1.9 | 4.3 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 1.9 | 1.1 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 3.8 | 2.2 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 3.3 | 0 |
| READ | Rectum adenocarcinoma | 122 | 1.9 | 1.1 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 11.3 | 12 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 15.1 | 13 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 1.9 | 3.3 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 1.9 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 11.3 | 9.8 | 0 |