Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| COAD | Colon adenocarcinoma | A311A | Silent | 2 |
| COAD | Colon adenocarcinoma | F84L | Missense | 2 |
| COAD | Colon adenocarcinoma | R683* | Nonsense | 2 |
| LUAD | Lung adenocarcinoma | L94L | Silent | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R126C | Missense | 2 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R32Q | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | D379H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D689H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E238K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E587* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | E687Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | F406L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K321* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | Q119* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | Q732H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R739H | Missense | 1 |
| BRCA | Breast invasive carcinoma | D886H | Missense | 1 |
| BRCA | Breast invasive carcinoma | E303K | Missense | 1 |
| BRCA | Breast invasive carcinoma | G711E | Missense | 1 |
| BRCA | Breast invasive carcinoma | R559T | Missense | 1 |
| BRCA | Breast invasive carcinoma | S707S | Silent | 1 |
| BRCA | Breast invasive carcinoma | Y863C | Missense | 1 |
| CESC | Cervical and endocervical cancers | E48Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | E550* | Nonsense | 1 |
| CESC | Cervical and endocervical cancers | E674* | Nonsense | 1 |
| CESC | Cervical and endocervical cancers | Q1010Q | Silent | 1 |
| COAD | Colon adenocarcinoma | D878G | Missense | 1 |
| COAD | Colon adenocarcinoma | E835* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | H800N | Missense | 1 |
| COAD | Colon adenocarcinoma | K298R | Missense | 1 |
| COAD | Colon adenocarcinoma | K571K | Silent | 1 |
| COAD | Colon adenocarcinoma | K767N | Missense | 1 |
| COAD | Colon adenocarcinoma | K865K | Silent | 1 |
| COAD | Colon adenocarcinoma | L466V | Missense | 1 |
| COAD | Colon adenocarcinoma | P248P | Silent | 1 |
| COAD | Colon adenocarcinoma | R126C | Missense | 1 |
| COAD | Colon adenocarcinoma | V93A | Missense | 1 |
| COAD | Colon adenocarcinoma | V93V | Silent | 1 |
| ESCA | Esophageal carcinoma | S634I | Missense | 1 |
| GBM | Glioblastoma multiforme | Q416P | Missense | 1 |
| GBM | Glioblastoma multiforme | Y29C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D293H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E690K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | I685V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | I998M | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K576E | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K737I | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L278L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | M898I | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P936P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q1010H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S478T | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V1017V | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | A179T | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | D99H | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | I722T | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | A286A | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | C497W | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | E56G | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | E860D | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | R263T | Missense | 1 |
| LGG | Brain Lower Grade Glioma | E557A | Missense | 1 |
| LGG | Brain Lower Grade Glioma | G268D | Missense | 1 |
| LGG | Brain Lower Grade Glioma | K851K | Silent | 1 |
| LGG | Brain Lower Grade Glioma | N841H | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R812Q | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | R683* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | A989V | Missense | 1 |
| LUAD | Lung adenocarcinoma | C221* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | D37E | Missense | 1 |
| LUAD | Lung adenocarcinoma | E39E | Silent | 1 |
| LUAD | Lung adenocarcinoma | G606W | Missense | 1 |
| LUAD | Lung adenocarcinoma | H563L | Missense | 1 |
| LUAD | Lung adenocarcinoma | H897L | Missense | 1 |
| LUAD | Lung adenocarcinoma | H897Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | K207R | Missense | 1 |
| LUAD | Lung adenocarcinoma | K298N | Missense | 1 |
| LUAD | Lung adenocarcinoma | K901* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | L25S | Missense | 1 |
| LUAD | Lung adenocarcinoma | L654L | Silent | 1 |
| LUAD | Lung adenocarcinoma | Q385P | Missense | 1 |
| LUAD | Lung adenocarcinoma | R499M | Missense | 1 |
| LUAD | Lung adenocarcinoma | R96P | Missense | 1 |
| LUAD | Lung adenocarcinoma | W734C | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G880A | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | I33V | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | L629L | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | Q817* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | R8L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | V924I | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | V93V | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | F240C | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | L374* | Nonsense | 1 |
| PAAD | Pancreatic adenocarcinoma | R18S | Missense | 1 |
| READ | Rectum adenocarcinoma | A311A | Silent | 1 |
| READ | Rectum adenocarcinoma | K791N | Missense | 1 |
| READ | Rectum adenocarcinoma | V969V | Silent | 1 |
| SARC | Sarcoma | C751* | Nonsense | 1 |
| SARC | Sarcoma | V227I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F663L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G912E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G980E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H46Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | K280N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P424P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | Q272* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | R126C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R8C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S599S | Silent | 1 |
| STAD | Stomach adenocarcinoma | C709F | Missense | 1 |
| STAD | Stomach adenocarcinoma | D646E | Missense | 1 |
| STAD | Stomach adenocarcinoma | E373E | Silent | 1 |
| STAD | Stomach adenocarcinoma | G440E | Missense | 1 |
| STAD | Stomach adenocarcinoma | H861Y | Missense | 1 |
| STAD | Stomach adenocarcinoma | I156I | Silent | 1 |
| STAD | Stomach adenocarcinoma | K547E | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q661R | Missense | 1 |
| STAD | Stomach adenocarcinoma | R66* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | S613N | Missense | 1 |
| STAD | Stomach adenocarcinoma | S809S | Silent | 1 |
| STAD | Stomach adenocarcinoma | T505A | Missense | 1 |
| STAD | Stomach adenocarcinoma | V924V | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | R348C | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | V708M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D552Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D83Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E592K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E934K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F84L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G142G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G77W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P436Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R126H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R130I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R277* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R413K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R612Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R683* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R833* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S359Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S613S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T858A | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 7 | 15.8 |
| BRCA | Breast invasive carcinoma | 976 | 3.4 | 5 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 3.4 | 1 | 10.5 |
| COAD | Colon adenocarcinoma | 367 | 20.7 | 9 | 15.8 |
| ESCA | Esophageal carcinoma | 185 | 0 | 1 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 2 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 10.3 | 9 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 3 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 3.4 | 4 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 3.4 | 4 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 0 | 5.3 |
| LUAD | Lung adenocarcinoma | 533 | 13.8 | 13 | 10.5 |
| LUSC | Lung squamous cell carcinoma | 177 | 3.4 | 4 | 5.3 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 3.4 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 2 | 5.3 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 6.9 | 1 | 0 |
| SARC | Sarcoma | 247 | 0 | 1 | 5.3 |
| SKCM | Skin Cutaneous Melanoma | 290 | 6.9 | 7 | 5.3 |
| STAD | Stomach adenocarcinoma | 393 | 13.8 | 8 | 5.3 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 2 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 6.9 | 17 | 15.8 |