Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | D648N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L328F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L6V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R314K | Missense | 1 |
| BRCA | Breast invasive carcinoma | A469A | Silent | 1 |
| BRCA | Breast invasive carcinoma | E329Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | A167A | Silent | 1 |
| CESC | Cervical and endocervical cancers | A671V | Missense | 1 |
| CESC | Cervical and endocervical cancers | E345K | Missense | 1 |
| CESC | Cervical and endocervical cancers | L138L | Silent | 1 |
| COAD | Colon adenocarcinoma | A143V | Missense | 1 |
| COAD | Colon adenocarcinoma | A655A | Silent | 1 |
| COAD | Colon adenocarcinoma | C503Y | Missense | 1 |
| COAD | Colon adenocarcinoma | E361E | Silent | 1 |
| COAD | Colon adenocarcinoma | L136L | Silent | 1 |
| COAD | Colon adenocarcinoma | R623H | Missense | 1 |
| COAD | Colon adenocarcinoma | T160T | Silent | 1 |
| COAD | Colon adenocarcinoma | T297M | Missense | 1 |
| COAD | Colon adenocarcinoma | T310A | Missense | 1 |
| ESCA | Esophageal carcinoma | P76L | Missense | 1 |
| ESCA | Esophageal carcinoma | T133A | Missense | 1 |
| ESCA | Esophageal carcinoma | T225I | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A161D | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A354E | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P398P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R430H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V404V | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | G641G | Silent | 1 |
| LGG | Brain Lower Grade Glioma | S497G | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | K334K | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | P221P | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | P546P | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | Q36R | Missense | 1 |
| LUAD | Lung adenocarcinoma | G188W | Missense | 1 |
| LUAD | Lung adenocarcinoma | L169L | Silent | 1 |
| LUAD | Lung adenocarcinoma | L6L | Silent | 1 |
| LUAD | Lung adenocarcinoma | P210S | Missense | 1 |
| LUAD | Lung adenocarcinoma | R359R | Silent | 1 |
| LUAD | Lung adenocarcinoma | R426R | Silent | 1 |
| LUAD | Lung adenocarcinoma | R495K | Missense | 1 |
| LUAD | Lung adenocarcinoma | T155T | Silent | 1 |
| LUAD | Lung adenocarcinoma | T466I | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G402E | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | Q93H | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | H282Q | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | P470H | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A191V | Missense | 1 |
| READ | Rectum adenocarcinoma | K566K | Silent | 1 |
| READ | Rectum adenocarcinoma | L231I | Missense | 1 |
| READ | Rectum adenocarcinoma | V471V | Silent | 1 |
| READ | Rectum adenocarcinoma | Y558Y | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | D489E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F269F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | I260I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P263P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P355P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P445L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q217K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R59W | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S497S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S614F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S666T | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | V64V | Silent | 1 |
| STAD | Stomach adenocarcinoma | A46D | Missense | 1 |
| STAD | Stomach adenocarcinoma | G627D | Missense | 1 |
| STAD | Stomach adenocarcinoma | H105H | Silent | 1 |
| STAD | Stomach adenocarcinoma | I156N | Missense | 1 |
| STAD | Stomach adenocarcinoma | L259R | Missense | 1 |
| STAD | Stomach adenocarcinoma | L266L | Silent | 1 |
| STAD | Stomach adenocarcinoma | R607Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | T160T | Silent | 1 |
| STAD | Stomach adenocarcinoma | T466A | Missense | 1 |
| STAD | Stomach adenocarcinoma | V215L | Missense | 1 |
| STAD | Stomach adenocarcinoma | V215V | Silent | 1 |
| STAD | Stomach adenocarcinoma | V287I | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | N115N | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | P647P | Silent | 1 |
| THCA | Thyroid carcinoma | C491C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I44L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L315L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L438L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q278H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R262M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T225I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T659T | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V284I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V370L | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 8 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 2.7 | 2 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 5.4 | 4 | 0 |
| COAD | Colon adenocarcinoma | 367 | 10.8 | 10 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 6 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 5.4 | 6 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 2.7 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 2 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 8.1 | 2 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 13.5 | 8 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 4 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 4 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 2 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 8.1 | 2 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 16.2 | 12 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 10.8 | 16 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 5.4 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 2.7 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 8.1 | 12 | 0 |