Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | L139L | Silent | 1 |
| BRCA | Breast invasive carcinoma | A246S | Missense | 1 |
| BRCA | Breast invasive carcinoma | I234V | Missense | 1 |
| BRCA | Breast invasive carcinoma | L139L | Silent | 1 |
| BRCA | Breast invasive carcinoma | R471H | Missense | 1 |
| CESC | Cervical and endocervical cancers | G127S | Missense | 1 |
| CESC | Cervical and endocervical cancers | L213L | Silent | 1 |
| COAD | Colon adenocarcinoma | A160A | Silent | 1 |
| COAD | Colon adenocarcinoma | A66V | Missense | 1 |
| COAD | Colon adenocarcinoma | P394S | Missense | 1 |
| COAD | Colon adenocarcinoma | Q493* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | D480E | Missense | 1 |
| ESCA | Esophageal carcinoma | E243Q | Missense | 1 |
| ESCA | Esophageal carcinoma | R300Q | Missense | 1 |
| ESCA | Esophageal carcinoma | S158N | Missense | 1 |
| ESCA | Esophageal carcinoma | S314S | Silent | 1 |
| ESCA | Esophageal carcinoma | T245T | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G406D | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G87V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P216P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R303W | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T51M | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T51S | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | P95H | Missense | 1 |
| LGG | Brain Lower Grade Glioma | F229F | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | L287P | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | Q472H | Missense | 1 |
| LUAD | Lung adenocarcinoma | A112S | Missense | 1 |
| LUAD | Lung adenocarcinoma | A125A | Silent | 1 |
| LUAD | Lung adenocarcinoma | A146A | Silent | 1 |
| LUAD | Lung adenocarcinoma | L464L | Silent | 1 |
| LUAD | Lung adenocarcinoma | P109H | Missense | 1 |
| LUAD | Lung adenocarcinoma | P165S | Missense | 1 |
| LUAD | Lung adenocarcinoma | P255Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | P522R | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q235Q | Silent | 1 |
| LUAD | Lung adenocarcinoma | Q241* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | S219* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | T167T | Silent | 1 |
| LUAD | Lung adenocarcinoma | W391* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | A162V | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | V169M | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | A280T | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | D89A | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A134T | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | L225L | Silent | 1 |
| PRAD | Prostate adenocarcinoma | A162T | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R90W | Missense | 1 |
| READ | Rectum adenocarcinoma | V106I | Missense | 1 |
| SARC | Sarcoma | L82F | Missense | 1 |
| SARC | Sarcoma | P92H | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E463K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F229F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G43E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G510R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G529S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G87D | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G87S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H226Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I183I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L462L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L82F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | N187D | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P109P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P126S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P212L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P216P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P218S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P222L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P224P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P251P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P271S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P371L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P371S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P79L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q297* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q528Q | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S175N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T167I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T44T | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | T500T | Silent | 1 |
| STAD | Stomach adenocarcinoma | A168A | Silent | 1 |
| STAD | Stomach adenocarcinoma | A261T | Missense | 1 |
| STAD | Stomach adenocarcinoma | L508L | Silent | 1 |
| STAD | Stomach adenocarcinoma | R88Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | S105S | Silent | 1 |
| STAD | Stomach adenocarcinoma | T167T | Silent | 1 |
| STAD | Stomach adenocarcinoma | T240M | Missense | 1 |
| STAD | Stomach adenocarcinoma | Y150Y | Silent | 1 |
| TGCT | Testicular Germ Cell Tumors | A312V | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | E463* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A116T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A66V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G389G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G87G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K402N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R192C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S244N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V55I | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 3.2 | 0 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 3.2 | 4.8 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 3.2 | 1.6 | 0 |
| COAD | Colon adenocarcinoma | 367 | 3.2 | 3.2 | 16.7 |
| ESCA | Esophageal carcinoma | 185 | 6.5 | 6.5 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 3.2 | 8.1 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 1.6 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 3.2 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 3.2 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 16.1 | 8.1 | 50 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 3.2 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 3.2 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 3.2 | 1.6 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 3.2 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 1.6 | 0 |
| SARC | Sarcoma | 247 | 0 | 3.2 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 32.3 | 30.6 | 16.7 |
| STAD | Stomach adenocarcinoma | 393 | 16.1 | 4.8 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 1.6 | 16.7 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 6.5 | 9.7 | 0 |