Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | A41G | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D264H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E334Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E68* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | R335K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S83F | Missense | 1 |
| BRCA | Breast invasive carcinoma | D141N | Missense | 1 |
| BRCA | Breast invasive carcinoma | N328Y | Missense | 1 |
| BRCA | Breast invasive carcinoma | R116Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | R274* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | A40V | Missense | 1 |
| COAD | Colon adenocarcinoma | T179T | Silent | 1 |
| ESCA | Esophageal carcinoma | G165V | Missense | 1 |
| GBM | Glioblastoma multiforme | E315Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D262N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R101R | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | C292S | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | G213V | Missense | 1 |
| LAML | Acute Myeloid Leukemia | C242Y | Missense | 1 |
| LAML | Acute Myeloid Leukemia | E139* | Nonsense | 1 |
| LAML | Acute Myeloid Leukemia | G287V | Missense | 1 |
| LGG | Brain Lower Grade Glioma | N137S | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | K132R | Missense | 1 |
| LUAD | Lung adenocarcinoma | A233G | Missense | 1 |
| LUAD | Lung adenocarcinoma | E189* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | H131Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | L324L | Silent | 1 |
| LUAD | Lung adenocarcinoma | Q251K | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G248C | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G63C | Missense | 1 |
| SARC | Sarcoma | H110Q | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A296A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | K164R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Y301Y | Silent | 1 |
| STAD | Stomach adenocarcinoma | N171I | Missense | 1 |
| STAD | Stomach adenocarcinoma | R319* | Nonsense | 1 |
| THCA | Thyroid carcinoma | G93C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E139K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E189D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K132N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K299N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R116Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S2* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S318S | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 15.6 | 16.7 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 9.4 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 0 | 16.7 |
| COAD | Colon adenocarcinoma | 367 | 16.7 | 3.1 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 3.1 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 3.1 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 16.7 | 3.1 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 6.2 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 6.2 | 16.7 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 3.1 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 3.1 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 16.7 | 9.4 | 16.7 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 6.2 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 0 | 0 |
| SARC | Sarcoma | 247 | 0 | 3.1 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 33.3 | 3.1 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 0 | 3.1 | 16.7 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 3.1 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 16.7 | 15.6 | 16.7 |