Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| SKCM | Skin Cutaneous Melanoma | P317S | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | E337K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R210Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | D284H | Missense | 1 |
| COAD | Colon adenocarcinoma | K211N | Missense | 1 |
| COAD | Colon adenocarcinoma | K87N | Missense | 1 |
| COAD | Colon adenocarcinoma | L335M | Missense | 1 |
| COAD | Colon adenocarcinoma | R359C | Missense | 1 |
| COAD | Colon adenocarcinoma | R71S | Missense | 1 |
| COAD | Colon adenocarcinoma | S131P | Missense | 1 |
| COAD | Colon adenocarcinoma | S313A | Missense | 1 |
| COAD | Colon adenocarcinoma | S56S | Silent | 1 |
| COAD | Colon adenocarcinoma | T3A | Missense | 1 |
| COAD | Colon adenocarcinoma | V57M | Missense | 1 |
| ESCA | Esophageal carcinoma | R244H | Missense | 1 |
| ESCA | Esophageal carcinoma | W343* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E165K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K354K | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K7N | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | L162L | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | Y245C | Missense | 1 |
| LGG | Brain Lower Grade Glioma | K104R | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | N54D | Missense | 1 |
| LUAD | Lung adenocarcinoma | E44* | Nonsense | 1 |
| OV | Ovarian serous cystadenocarcinoma | A250A | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | F60V | Missense | 1 |
| PCPG | Pheochromocytoma and Paraganglioma | C276C | Silent | 1 |
| PRAD | Prostate adenocarcinoma | H200Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A303V | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | C300C | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G280E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I373I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | Q151* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | R145C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R267R | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R289K | Missense | 1 |
| STAD | Stomach adenocarcinoma | P69H | Missense | 1 |
| THCA | Thyroid carcinoma | Q151Q | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D260Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E212* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P69H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R92Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T196A | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 6.5 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 3.2 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 0 | 0 |
| COAD | Colon adenocarcinoma | 367 | 11.1 | 29 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 3.2 | 25 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 11.1 | 6.5 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 11.1 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 3.2 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 3.2 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 3.2 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 0 | 0 | 25 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 0 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 11.1 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 3.2 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 11.1 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 3.2 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 0 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 33.3 | 19.4 | 25 |
| STAD | Stomach adenocarcinoma | 393 | 0 | 3.2 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 11.1 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 0 | 12.9 | 25 |