Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| STAD | Stomach adenocarcinoma | H1143H | Silent | 2 |
| STAD | Stomach adenocarcinoma | S1264S | Silent | 2 |
| BLCA | Bladder urothelial carcinoma | A317V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | C1123Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | C154S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E195K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E280K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | F226F | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | G1015G | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | I711I | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L1314L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L151V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q326E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R1119W | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R378T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R614Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R992L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S1373F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S432F | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | T322S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | T822T | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | V1624M | Missense | 1 |
| BRCA | Breast invasive carcinoma | A424A | Silent | 1 |
| BRCA | Breast invasive carcinoma | D148N | Missense | 1 |
| BRCA | Breast invasive carcinoma | E828K | Missense | 1 |
| BRCA | Breast invasive carcinoma | R1179W | Missense | 1 |
| BRCA | Breast invasive carcinoma | R374* | Nonsense | 1 |
| BRCA | Breast invasive carcinoma | T1341P | Missense | 1 |
| BRCA | Breast invasive carcinoma | T799T | Silent | 1 |
| BRCA | Breast invasive carcinoma | T890I | Missense | 1 |
| CESC | Cervical and endocervical cancers | C949Y | Missense | 1 |
| CESC | Cervical and endocervical cancers | E1573K | Missense | 1 |
| CESC | Cervical and endocervical cancers | E918Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | F632F | Silent | 1 |
| CESC | Cervical and endocervical cancers | L531L | Silent | 1 |
| CESC | Cervical and endocervical cancers | P146A | Missense | 1 |
| CESC | Cervical and endocervical cancers | S430C | Missense | 1 |
| COAD | Colon adenocarcinoma | A1278T | Missense | 1 |
| COAD | Colon adenocarcinoma | A646A | Silent | 1 |
| COAD | Colon adenocarcinoma | G53V | Missense | 1 |
| COAD | Colon adenocarcinoma | K1006Q | Missense | 1 |
| COAD | Colon adenocarcinoma | K1136K | Silent | 1 |
| COAD | Colon adenocarcinoma | P183L | Missense | 1 |
| COAD | Colon adenocarcinoma | P402T | Missense | 1 |
| COAD | Colon adenocarcinoma | P669Q | Missense | 1 |
| COAD | Colon adenocarcinoma | Q372Q | Silent | 1 |
| COAD | Colon adenocarcinoma | R158R | Silent | 1 |
| COAD | Colon adenocarcinoma | S480S | Silent | 1 |
| COAD | Colon adenocarcinoma | V171A | Missense | 1 |
| COAD | Colon adenocarcinoma | V481M | Missense | 1 |
| ESCA | Esophageal carcinoma | P852P | Silent | 1 |
| ESCA | Esophageal carcinoma | R374* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | T293T | Silent | 1 |
| GBM | Glioblastoma multiforme | A646V | Missense | 1 |
| GBM | Glioblastoma multiforme | D975V | Missense | 1 |
| GBM | Glioblastoma multiforme | P569Q | Missense | 1 |
| GBM | Glioblastoma multiforme | P938S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A1622V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A596A | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D103N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D1258N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D193N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E137K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E920Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G721G | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | I1578F | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L217L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L422L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L433V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P592S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R1092L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R1171S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R1181L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S101C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S1373C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S511W | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S814L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | V347L | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E1122E | Silent | 1 |
| KIRC | Kidney renal clear cell carcinoma | P937P | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | G319D | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | P474P | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | S364P | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A1033A | Silent | 1 |
| LGG | Brain Lower Grade Glioma | A610V | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A901T | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A96T | Missense | 1 |
| LGG | Brain Lower Grade Glioma | E187G | Missense | 1 |
| LGG | Brain Lower Grade Glioma | F1274C | Missense | 1 |
| LGG | Brain Lower Grade Glioma | P935S | Missense | 1 |
| LGG | Brain Lower Grade Glioma | T122T | Silent | 1 |
| LGG | Brain Lower Grade Glioma | T1234M | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | A1364A | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | D1625E | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | H1227D | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | L112L | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | L200L | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | L506L | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | P1482L | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | P1508L | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | R1181L | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | S549S | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | S948F | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | V249G | Missense | 1 |
| LUAD | Lung adenocarcinoma | A119P | Missense | 1 |
| LUAD | Lung adenocarcinoma | A1278T | Missense | 1 |
| LUAD | Lung adenocarcinoma | A646V | Missense | 1 |
| LUAD | Lung adenocarcinoma | G162V | Missense | 1 |
| LUAD | Lung adenocarcinoma | I819M | Missense | 1 |
| LUAD | Lung adenocarcinoma | L1132L | Silent | 1 |
| LUAD | Lung adenocarcinoma | P1334P | Silent | 1 |
| LUAD | Lung adenocarcinoma | Q160E | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q926H | Missense | 1 |
| LUAD | Lung adenocarcinoma | R1219K | Missense | 1 |
| LUAD | Lung adenocarcinoma | S925R | Missense | 1 |
| LUAD | Lung adenocarcinoma | V1624M | Missense | 1 |
| LUAD | Lung adenocarcinoma | V481L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | A1622G | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | E848K | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G927C | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R1018L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S1124S | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | S358C | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | C186S | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | S101Y | Missense | 1 |
| PCPG | Pheochromocytoma and Paraganglioma | P409S | Missense | 1 |
| PRAD | Prostate adenocarcinoma | G853S | Missense | 1 |
| PRAD | Prostate adenocarcinoma | P16L | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R277Q | Missense | 1 |
| PRAD | Prostate adenocarcinoma | R614R | Silent | 1 |
| READ | Rectum adenocarcinoma | A1204A | Silent | 1 |
| READ | Rectum adenocarcinoma | A1366V | Missense | 1 |
| SARC | Sarcoma | E1573D | Missense | 1 |
| SARC | Sarcoma | G427V | Missense | 1 |
| SARC | Sarcoma | I165V | Missense | 1 |
| SARC | Sarcoma | R303C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A119A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | A1267A | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | A1267V | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E1144K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F555F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | I393I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | K1598R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L1314L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P1146L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P1243P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P663L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R158* | Nonsense | 1 |
| SKCM | Skin Cutaneous Melanoma | S1313S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S1332L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S144F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S250F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S465S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S73S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S755F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | V770V | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | Y129D | Missense | 1 |
| STAD | Stomach adenocarcinoma | A1523T | Missense | 1 |
| STAD | Stomach adenocarcinoma | A232A | Silent | 1 |
| STAD | Stomach adenocarcinoma | A312V | Missense | 1 |
| STAD | Stomach adenocarcinoma | A424A | Silent | 1 |
| STAD | Stomach adenocarcinoma | A646A | Silent | 1 |
| STAD | Stomach adenocarcinoma | A911D | Missense | 1 |
| STAD | Stomach adenocarcinoma | D58G | Missense | 1 |
| STAD | Stomach adenocarcinoma | D603G | Missense | 1 |
| STAD | Stomach adenocarcinoma | E314K | Missense | 1 |
| STAD | Stomach adenocarcinoma | G1015G | Silent | 1 |
| STAD | Stomach adenocarcinoma | G897R | Missense | 1 |
| STAD | Stomach adenocarcinoma | K360N | Missense | 1 |
| STAD | Stomach adenocarcinoma | K823E | Missense | 1 |
| STAD | Stomach adenocarcinoma | L642L | Silent | 1 |
| STAD | Stomach adenocarcinoma | Q1282L | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1188Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R1631R | Silent | 1 |
| STAD | Stomach adenocarcinoma | R194C | Missense | 1 |
| STAD | Stomach adenocarcinoma | R337W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R994H | Missense | 1 |
| STAD | Stomach adenocarcinoma | S192G | Missense | 1 |
| STAD | Stomach adenocarcinoma | S306T | Missense | 1 |
| STAD | Stomach adenocarcinoma | T396M | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | A786S | Missense | 1 |
| THCA | Thyroid carcinoma | C134Y | Missense | 1 |
| THCA | Thyroid carcinoma | T872T | Silent | 1 |
| THYM | Thymoma | A1398A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A1005V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A1414T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A1523T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A61A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C1491C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D1277N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E137K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E1452K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F777F | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G1649G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P1239P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1131R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R149Q | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R374* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R527R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R659C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R673I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R681M | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 7.8 | 11 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 3.1 | 3.7 | 25 |
| CESC | Cervical and endocervical cancers | 194 | 3.1 | 3.7 | 0 |
| COAD | Colon adenocarcinoma | 367 | 7.8 | 5.9 | 0 |
| ESCA | Esophageal carcinoma | 185 | 3.1 | 0 | 25 |
| GBM | Glioblastoma multiforme | 283 | 0 | 2.9 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 6.2 | 12.5 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 3.1 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 1.6 | 1.5 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 3.1 | 5.1 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 7.8 | 5.1 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 3.1 | 8.1 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 1.6 | 3.7 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0.7 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0.7 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0.7 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 1.6 | 2.2 | 0 |
| READ | Rectum adenocarcinoma | 122 | 1.6 | 0.7 | 0 |
| SARC | Sarcoma | 247 | 0 | 2.9 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 15.6 | 7.4 | 25 |
| STAD | Stomach adenocarcinoma | 393 | 15.6 | 12.5 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0.7 | 0 |
| THCA | Thyroid carcinoma | 495 | 1.6 | 0.7 | 0 |
| THYM | Thymoma | 119 | 1.6 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 10.9 | 7.4 | 25 |