Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | S420L | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | D141N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E292Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E413Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G150C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G491S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I249I | Silent | 1 |
| BRCA | Breast invasive carcinoma | A424A | Silent | 1 |
| BRCA | Breast invasive carcinoma | L65L | Silent | 1 |
| BRCA | Breast invasive carcinoma | V309V | Silent | 1 |
| BRCA | Breast invasive carcinoma | V352G | Missense | 1 |
| CESC | Cervical and endocervical cancers | G177S | Missense | 1 |
| CESC | Cervical and endocervical cancers | L337L | Silent | 1 |
| CESC | Cervical and endocervical cancers | R277R | Silent | 1 |
| CESC | Cervical and endocervical cancers | T59M | Missense | 1 |
| COAD | Colon adenocarcinoma | A143A | Silent | 1 |
| COAD | Colon adenocarcinoma | D374A | Missense | 1 |
| COAD | Colon adenocarcinoma | N167N | Silent | 1 |
| COAD | Colon adenocarcinoma | R285S | Missense | 1 |
| COAD | Colon adenocarcinoma | V137M | Missense | 1 |
| COAD | Colon adenocarcinoma | V326V | Silent | 1 |
| ESCA | Esophageal carcinoma | W195C | Missense | 1 |
| ESCA | Esophageal carcinoma | W399L | Missense | 1 |
| GBM | Glioblastoma multiforme | E31K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E226D | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | I365I | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | M264I | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R256Q | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | R456W | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S487L | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | E344K | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | S101R | Missense | 1 |
| LGG | Brain Lower Grade Glioma | L307I | Missense | 1 |
| LGG | Brain Lower Grade Glioma | M4V | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R319C | Missense | 1 |
| LGG | Brain Lower Grade Glioma | R94H | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | D435N | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | E41G | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | G391G | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | I183T | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | I249I | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | M496I | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | T59T | Silent | 1 |
| LUAD | Lung adenocarcinoma | A18A | Silent | 1 |
| LUAD | Lung adenocarcinoma | C16F | Missense | 1 |
| LUAD | Lung adenocarcinoma | G138C | Missense | 1 |
| LUAD | Lung adenocarcinoma | G395V | Missense | 1 |
| LUAD | Lung adenocarcinoma | G395W | Missense | 1 |
| LUAD | Lung adenocarcinoma | H276D | Missense | 1 |
| LUAD | Lung adenocarcinoma | I13I | Silent | 1 |
| LUAD | Lung adenocarcinoma | I183I | Silent | 1 |
| LUAD | Lung adenocarcinoma | K214T | Missense | 1 |
| LUAD | Lung adenocarcinoma | L347V | Missense | 1 |
| LUAD | Lung adenocarcinoma | L462I | Missense | 1 |
| LUAD | Lung adenocarcinoma | R142R | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | D95Y | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | H437D | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | V50L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | W399* | Nonsense | 1 |
| OV | Ovarian serous cystadenocarcinoma | K407M | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A375T | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A380E | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | P474L | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | V455V | Silent | 1 |
| READ | Rectum adenocarcinoma | E348K | Missense | 1 |
| SARC | Sarcoma | A49A | Silent | 1 |
| SARC | Sarcoma | C22S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | A350T | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D211N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D322N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E261K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F117F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | I170I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | I175S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P471S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R30K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S431F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T213T | Silent | 1 |
| STAD | Stomach adenocarcinoma | A144V | Missense | 1 |
| STAD | Stomach adenocarcinoma | A380V | Missense | 1 |
| STAD | Stomach adenocarcinoma | E413K | Missense | 1 |
| STAD | Stomach adenocarcinoma | M151T | Missense | 1 |
| STAD | Stomach adenocarcinoma | S346P | Missense | 1 |
| STAD | Stomach adenocarcinoma | V163M | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | G92W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A350V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I175I | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I97I | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K492T | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R450C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R456W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S269I | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 4.2 | 10.3 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 12.5 | 1.5 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 8.3 | 2.9 | 0 |
| COAD | Colon adenocarcinoma | 367 | 12.5 | 4.4 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 2.9 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 1.5 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 4.2 | 7.4 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 1.5 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 1.5 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 5.9 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 12.5 | 5.9 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 16.7 | 11.8 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 4.4 | 100 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 1.5 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 4.2 | 4.4 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 1.5 | 0 |
| SARC | Sarcoma | 247 | 4.2 | 1.5 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 12.5 | 11.8 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 0 | 8.8 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 1.5 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 8.3 | 7.4 | 0 |