Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | L100L | Silent | 1 |
| BRCA | Breast invasive carcinoma | K187N | Missense | 1 |
| CESC | Cervical and endocervical cancers | F280F | Silent | 1 |
| COAD | Colon adenocarcinoma | I180I | Silent | 1 |
| COAD | Colon adenocarcinoma | R158W | Missense | 1 |
| COAD | Colon adenocarcinoma | S73S | Silent | 1 |
| GBM | Glioblastoma multiforme | A236T | Missense | 1 |
| GBM | Glioblastoma multiforme | A25T | Missense | 1 |
| GBM | Glioblastoma multiforme | G181S | Missense | 1 |
| GBM | Glioblastoma multiforme | I28I | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A25A | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S94C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T112N | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | A123V | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | I150I | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | H265Y | Missense | 1 |
| LGG | Brain Lower Grade Glioma | H206Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | L210L | Silent | 1 |
| LUAD | Lung adenocarcinoma | S80C | Missense | 1 |
| LUAD | Lung adenocarcinoma | Y202* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | Q310* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | W137* | Nonsense | 1 |
| PAAD | Pancreatic adenocarcinoma | R40H | Missense | 1 |
| READ | Rectum adenocarcinoma | E170K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D151N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F230F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G203E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L6L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | T208I | Missense | 1 |
| STAD | Stomach adenocarcinoma | L100L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D151N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R168C | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 9.1 | 0 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 5.6 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 9.1 | 0 | 0 |
| COAD | Colon adenocarcinoma | 367 | 18.2 | 5.6 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 0 | 0 |
| GBM | Glioblastoma multiforme | 283 | 9.1 | 16.7 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 9.1 | 11.1 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 9.1 | 5.6 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 5.6 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 5.6 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 0 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 9.1 | 5.6 | 33.3 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 0 | 66.7 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 5.6 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 5.6 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 18.2 | 16.7 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 9.1 | 0 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 0 | 11.1 | 0 |