Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| SKCM | Skin Cutaneous Melanoma | P180S | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | A1310A | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | A956A | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | D979H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E228D | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K1203N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | L717V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | M1240I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | Q1343H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R114W | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R1245Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R174C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R447S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | T1358N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | V100V | Silent | 1 |
| BRCA | Breast invasive carcinoma | D533H | Missense | 1 |
| BRCA | Breast invasive carcinoma | E300Q | Missense | 1 |
| BRCA | Breast invasive carcinoma | N1437S | Missense | 1 |
| BRCA | Breast invasive carcinoma | S1321S | Silent | 1 |
| BRCA | Breast invasive carcinoma | S323S | Silent | 1 |
| CESC | Cervical and endocervical cancers | E1184Q | Missense | 1 |
| CESC | Cervical and endocervical cancers | E1283K | Missense | 1 |
| CESC | Cervical and endocervical cancers | I728M | Missense | 1 |
| CESC | Cervical and endocervical cancers | R1180S | Missense | 1 |
| COAD | Colon adenocarcinoma | F441F | Silent | 1 |
| COAD | Colon adenocarcinoma | G1118V | Missense | 1 |
| COAD | Colon adenocarcinoma | G1335G | Silent | 1 |
| COAD | Colon adenocarcinoma | G732R | Missense | 1 |
| COAD | Colon adenocarcinoma | I662I | Silent | 1 |
| COAD | Colon adenocarcinoma | K212K | Silent | 1 |
| COAD | Colon adenocarcinoma | N552D | Missense | 1 |
| COAD | Colon adenocarcinoma | R1028H | Missense | 1 |
| COAD | Colon adenocarcinoma | R1043C | Missense | 1 |
| COAD | Colon adenocarcinoma | R361Q | Missense | 1 |
| COAD | Colon adenocarcinoma | R421* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | R758C | Missense | 1 |
| COAD | Colon adenocarcinoma | R873C | Missense | 1 |
| COAD | Colon adenocarcinoma | R881* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | T656A | Missense | 1 |
| ESCA | Esophageal carcinoma | A624S | Missense | 1 |
| ESCA | Esophageal carcinoma | C767* | Nonsense | 1 |
| ESCA | Esophageal carcinoma | G543G | Silent | 1 |
| ESCA | Esophageal carcinoma | G584C | Missense | 1 |
| ESCA | Esophageal carcinoma | P1433P | Silent | 1 |
| ESCA | Esophageal carcinoma | P196S | Missense | 1 |
| ESCA | Esophageal carcinoma | R1073H | Missense | 1 |
| ESCA | Esophageal carcinoma | V1390M | Missense | 1 |
| GBM | Glioblastoma multiforme | C1230Y | Missense | 1 |
| GBM | Glioblastoma multiforme | G156E | Missense | 1 |
| GBM | Glioblastoma multiforme | G329S | Missense | 1 |
| GBM | Glioblastoma multiforme | H1219H | Silent | 1 |
| GBM | Glioblastoma multiforme | P297S | Missense | 1 |
| GBM | Glioblastoma multiforme | R880W | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A203A | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E1434* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K969E | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S697S | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T1455M | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | D1220V | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | V266A | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | A1497V | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | L1008L | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | Q1228P | Missense | 1 |
| LGG | Brain Lower Grade Glioma | D466D | Silent | 1 |
| LGG | Brain Lower Grade Glioma | G1335G | Silent | 1 |
| LGG | Brain Lower Grade Glioma | I955I | Silent | 1 |
| LGG | Brain Lower Grade Glioma | R1242Q | Missense | 1 |
| LGG | Brain Lower Grade Glioma | S1453Y | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | A1288T | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | A12V | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | M276L | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | Q1439Q | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | T1351T | Silent | 1 |
| LIHC | Liver hepatocellular carcinoma | T825T | Silent | 1 |
| LUAD | Lung adenocarcinoma | A1310A | Silent | 1 |
| LUAD | Lung adenocarcinoma | A525V | Missense | 1 |
| LUAD | Lung adenocarcinoma | C314F | Missense | 1 |
| LUAD | Lung adenocarcinoma | E1072Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | E1279* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | E300Q | Missense | 1 |
| LUAD | Lung adenocarcinoma | G635G | Silent | 1 |
| LUAD | Lung adenocarcinoma | K1132N | Missense | 1 |
| LUAD | Lung adenocarcinoma | P1431P | Silent | 1 |
| LUAD | Lung adenocarcinoma | P6T | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q1496H | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q705Q | Silent | 1 |
| LUAD | Lung adenocarcinoma | R114P | Missense | 1 |
| LUAD | Lung adenocarcinoma | R864L | Missense | 1 |
| LUAD | Lung adenocarcinoma | S842S | Silent | 1 |
| LUAD | Lung adenocarcinoma | V1109I | Missense | 1 |
| LUAD | Lung adenocarcinoma | W452L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | A1126T | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | K745N | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | R864L | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | G1458G | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | P655A | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | A490V | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | C1142Y | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R4H | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | R776H | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A1224V | Missense | 1 |
| PRAD | Prostate adenocarcinoma | H227H | Silent | 1 |
| READ | Rectum adenocarcinoma | K1233N | Missense | 1 |
| READ | Rectum adenocarcinoma | V1409M | Missense | 1 |
| SARC | Sarcoma | F939Y | Missense | 1 |
| SARC | Sarcoma | H1243Q | Missense | 1 |
| SARC | Sarcoma | T1413I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | C740G | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D1048E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E778D | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F238F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | F463F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | H951H | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | I1055I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | I955I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P443L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P905L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q1428Q | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S1361S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S591S | Silent | 1 |
| STAD | Stomach adenocarcinoma | A1490A | Silent | 1 |
| STAD | Stomach adenocarcinoma | A492V | Missense | 1 |
| STAD | Stomach adenocarcinoma | C1230C | Silent | 1 |
| STAD | Stomach adenocarcinoma | F441F | Silent | 1 |
| STAD | Stomach adenocarcinoma | K1187R | Missense | 1 |
| STAD | Stomach adenocarcinoma | L731L | Silent | 1 |
| STAD | Stomach adenocarcinoma | N1050N | Silent | 1 |
| STAD | Stomach adenocarcinoma | R611W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R679W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R996Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | S902S | Silent | 1 |
| STAD | Stomach adenocarcinoma | T1197M | Missense | 1 |
| STAD | Stomach adenocarcinoma | T1468T | Silent | 1 |
| STAD | Stomach adenocarcinoma | V1215I | Missense | 1 |
| THCA | Thyroid carcinoma | G925S | Missense | 1 |
| THCA | Thyroid carcinoma | L647V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A889A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C1058C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C1159Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C1230C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C292C | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G543G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | H1106Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | H1214H | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | I649I | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | P603P | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1043C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R1147C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R174H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S169I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S504S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V1276I | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y1205Y | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 5.7 | 11.5 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 3.8 | 3.1 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 4.2 | 0 |
| COAD | Colon adenocarcinoma | 367 | 7.5 | 9.4 | 40 |
| ESCA | Esophageal carcinoma | 185 | 3.8 | 5.2 | 20 |
| GBM | Glioblastoma multiforme | 283 | 1.9 | 5.2 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 3.8 | 2.1 | 20 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 2.1 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 1.9 | 2.1 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 5.7 | 2.1 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 5.7 | 3.1 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 9.4 | 11.5 | 20 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 3.1 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 1.9 | 1 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 4.2 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 1.9 | 1 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 2.1 | 0 |
| SARC | Sarcoma | 247 | 0 | 3.1 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 15.1 | 7.3 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 13.2 | 7.3 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 2.1 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 18.9 | 7.3 | 0 |