Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | E271Q | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | *1277* | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | A34E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | A417T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D624N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E1180* | Nonsense | 1 |
| BLCA | Bladder urothelial carcinoma | E85K | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | E884Q | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G454C | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | G650A | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K170R | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K249N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P512P | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | P67P | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | P936L | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R962S | Missense | 1 |
| BRCA | Breast invasive carcinoma | A1163T | Missense | 1 |
| BRCA | Breast invasive carcinoma | A561A | Silent | 1 |
| BRCA | Breast invasive carcinoma | D760D | Silent | 1 |
| BRCA | Breast invasive carcinoma | R173H | Missense | 1 |
| BRCA | Breast invasive carcinoma | V629M | Missense | 1 |
| BRCA | Breast invasive carcinoma | Y194C | Missense | 1 |
| CESC | Cervical and endocervical cancers | E267K | Missense | 1 |
| CESC | Cervical and endocervical cancers | E37K | Missense | 1 |
| CESC | Cervical and endocervical cancers | G690R | Missense | 1 |
| CESC | Cervical and endocervical cancers | S153N | Missense | 1 |
| CESC | Cervical and endocervical cancers | S918S | Silent | 1 |
| CESC | Cervical and endocervical cancers | T229T | Silent | 1 |
| COAD | Colon adenocarcinoma | A573A | Silent | 1 |
| COAD | Colon adenocarcinoma | D1070D | Silent | 1 |
| COAD | Colon adenocarcinoma | D1123D | Silent | 1 |
| COAD | Colon adenocarcinoma | D1197N | Missense | 1 |
| COAD | Colon adenocarcinoma | D628D | Silent | 1 |
| COAD | Colon adenocarcinoma | D632D | Silent | 1 |
| COAD | Colon adenocarcinoma | E338K | Missense | 1 |
| COAD | Colon adenocarcinoma | F290L | Missense | 1 |
| COAD | Colon adenocarcinoma | G707S | Missense | 1 |
| COAD | Colon adenocarcinoma | H416H | Silent | 1 |
| COAD | Colon adenocarcinoma | K778K | Silent | 1 |
| COAD | Colon adenocarcinoma | N161D | Missense | 1 |
| COAD | Colon adenocarcinoma | N161S | Missense | 1 |
| COAD | Colon adenocarcinoma | P462S | Missense | 1 |
| COAD | Colon adenocarcinoma | R1199H | Missense | 1 |
| COAD | Colon adenocarcinoma | R336C | Missense | 1 |
| COAD | Colon adenocarcinoma | R357C | Missense | 1 |
| COAD | Colon adenocarcinoma | R411R | Silent | 1 |
| COAD | Colon adenocarcinoma | R986C | Missense | 1 |
| COAD | Colon adenocarcinoma | S560S | Silent | 1 |
| COAD | Colon adenocarcinoma | T404M | Missense | 1 |
| COAD | Colon adenocarcinoma | T618A | Missense | 1 |
| COAD | Colon adenocarcinoma | Y73Y | Silent | 1 |
| ESCA | Esophageal carcinoma | A643S | Missense | 1 |
| ESCA | Esophageal carcinoma | D774Y | Missense | 1 |
| ESCA | Esophageal carcinoma | E1219Q | Missense | 1 |
| ESCA | Esophageal carcinoma | G1018G | Silent | 1 |
| ESCA | Esophageal carcinoma | S797S | Silent | 1 |
| GBM | Glioblastoma multiforme | A689A | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A458D | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A654S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A654V | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D225N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | D636H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E266K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E902* | Nonsense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | I959S | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | L224L | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P393L | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | P67P | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q1020Q | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | T621T | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Y251D | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | D917D | Silent | 1 |
| KIRP | Kidney renal papillary cell carcinoma | H1032R | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | H355N | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | S921S | Silent | 1 |
| LAML | Acute Myeloid Leukemia | V588M | Missense | 1 |
| LGG | Brain Lower Grade Glioma | G15S | Missense | 1 |
| LGG | Brain Lower Grade Glioma | H366H | Silent | 1 |
| LGG | Brain Lower Grade Glioma | R1025Q | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | F84Y | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | H1032L | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | L264Q | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | L528Q | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | R846W | Missense | 1 |
| LUAD | Lung adenocarcinoma | A259A | Silent | 1 |
| LUAD | Lung adenocarcinoma | A561A | Silent | 1 |
| LUAD | Lung adenocarcinoma | A746G | Missense | 1 |
| LUAD | Lung adenocarcinoma | D544D | Silent | 1 |
| LUAD | Lung adenocarcinoma | D616Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | D624H | Missense | 1 |
| LUAD | Lung adenocarcinoma | D624Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | D742Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | E1084* | Nonsense | 1 |
| LUAD | Lung adenocarcinoma | E1120K | Missense | 1 |
| LUAD | Lung adenocarcinoma | E1203K | Missense | 1 |
| LUAD | Lung adenocarcinoma | F230S | Missense | 1 |
| LUAD | Lung adenocarcinoma | G1103C | Missense | 1 |
| LUAD | Lung adenocarcinoma | G574R | Missense | 1 |
| LUAD | Lung adenocarcinoma | G601C | Missense | 1 |
| LUAD | Lung adenocarcinoma | G657W | Missense | 1 |
| LUAD | Lung adenocarcinoma | G947R | Missense | 1 |
| LUAD | Lung adenocarcinoma | K122N | Missense | 1 |
| LUAD | Lung adenocarcinoma | K284N | Missense | 1 |
| LUAD | Lung adenocarcinoma | K401N | Missense | 1 |
| LUAD | Lung adenocarcinoma | M709I | Missense | 1 |
| LUAD | Lung adenocarcinoma | P1036L | Missense | 1 |
| LUAD | Lung adenocarcinoma | P495L | Missense | 1 |
| LUAD | Lung adenocarcinoma | R307R | Silent | 1 |
| LUAD | Lung adenocarcinoma | R743* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | D1070E | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | G111G | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | G484V | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | I387I | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | R247L | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | S1138W | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | Y951C | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | G651G | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | F156F | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | R873Q | Missense | 1 |
| PCPG | Pheochromocytoma and Paraganglioma | Y403Y | Silent | 1 |
| PRAD | Prostate adenocarcinoma | G1018R | Missense | 1 |
| PRAD | Prostate adenocarcinoma | G687G | Silent | 1 |
| PRAD | Prostate adenocarcinoma | S586P | Missense | 1 |
| PRAD | Prostate adenocarcinoma | S627S | Silent | 1 |
| READ | Rectum adenocarcinoma | F579F | Silent | 1 |
| READ | Rectum adenocarcinoma | L625M | Missense | 1 |
| SARC | Sarcoma | A845A | Silent | 1 |
| SARC | Sarcoma | P524H | Missense | 1 |
| SARC | Sarcoma | S1074S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | A1205V | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D1210N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D312N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | D760N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E1121K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E1203E | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | E1266K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E141K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E201K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E237K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E37K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E576K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E701K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E800K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E884K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | E909D | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F290F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | F514F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | F725F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G1042G | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G1193G | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G263D | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G263S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G650R | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G919D | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G919S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | H1247Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I1076I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | I1100I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | K1209N | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L547L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L745L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | N1014N | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P24P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P490L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P490S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P53L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P71L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P720L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P784L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P787H | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P787L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P787P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | P92S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | Q383P | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R1015C | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | R307R | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R888R | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S1241F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S358L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S491F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S521F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S698S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S940F | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S940S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | S992S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | V343V | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | Y261N | Missense | 1 |
| STAD | Stomach adenocarcinoma | A376A | Silent | 1 |
| STAD | Stomach adenocarcinoma | A417T | Missense | 1 |
| STAD | Stomach adenocarcinoma | A509T | Missense | 1 |
| STAD | Stomach adenocarcinoma | A663A | Silent | 1 |
| STAD | Stomach adenocarcinoma | A916A | Silent | 1 |
| STAD | Stomach adenocarcinoma | D1066D | Silent | 1 |
| STAD | Stomach adenocarcinoma | D1122D | Silent | 1 |
| STAD | Stomach adenocarcinoma | D418N | Missense | 1 |
| STAD | Stomach adenocarcinoma | D544N | Missense | 1 |
| STAD | Stomach adenocarcinoma | D597N | Missense | 1 |
| STAD | Stomach adenocarcinoma | D781D | Silent | 1 |
| STAD | Stomach adenocarcinoma | E1266E | Silent | 1 |
| STAD | Stomach adenocarcinoma | E237K | Missense | 1 |
| STAD | Stomach adenocarcinoma | E576K | Missense | 1 |
| STAD | Stomach adenocarcinoma | E754K | Missense | 1 |
| STAD | Stomach adenocarcinoma | F230L | Missense | 1 |
| STAD | Stomach adenocarcinoma | F290F | Silent | 1 |
| STAD | Stomach adenocarcinoma | F579L | Missense | 1 |
| STAD | Stomach adenocarcinoma | L110P | Missense | 1 |
| STAD | Stomach adenocarcinoma | N1082N | Silent | 1 |
| STAD | Stomach adenocarcinoma | P1188P | Silent | 1 |
| STAD | Stomach adenocarcinoma | P349P | Silent | 1 |
| STAD | Stomach adenocarcinoma | P526P | Silent | 1 |
| STAD | Stomach adenocarcinoma | P656P | Silent | 1 |
| STAD | Stomach adenocarcinoma | R231H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R420H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R525Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | R971W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R999Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | S277S | Silent | 1 |
| STAD | Stomach adenocarcinoma | S379S | Silent | 1 |
| STAD | Stomach adenocarcinoma | T1092I | Missense | 1 |
| STAD | Stomach adenocarcinoma | T390M | Missense | 1 |
| STAD | Stomach adenocarcinoma | T741T | Silent | 1 |
| STAD | Stomach adenocarcinoma | V17I | Missense | 1 |
| STAD | Stomach adenocarcinoma | V662M | Missense | 1 |
| STAD | Stomach adenocarcinoma | Y738* | Nonsense | 1 |
| TGCT | Testicular Germ Cell Tumors | A689S | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | A845V | Missense | 1 |
| THCA | Thyroid carcinoma | P55L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A163V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A175V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A964V | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C1013Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D628N | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E237K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | F1008L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G1181G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L908M | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N816N | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q1020H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q140H | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R357C | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R525W | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S44L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S475S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T1142T | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V1260V | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V196V | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 3.7 | 8.1 | 20 |
| BRCA | Breast invasive carcinoma | 976 | 2.4 | 2.5 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 2.4 | 2.5 | 0 |
| COAD | Colon adenocarcinoma | 367 | 12.2 | 8.1 | 0 |
| ESCA | Esophageal carcinoma | 185 | 2.4 | 1.9 | 0 |
| GBM | Glioblastoma multiforme | 283 | 1.2 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 4.9 | 5.6 | 20 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 2.4 | 1.2 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0.6 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 1.2 | 1.2 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 3.1 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 4.9 | 11.9 | 40 |
| LUSC | Lung squamous cell carcinoma | 177 | 2.4 | 3.1 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 1.2 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 1.2 | 0.6 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 1.2 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 2.4 | 1.2 | 0 |
| READ | Rectum adenocarcinoma | 122 | 1.2 | 0.6 | 0 |
| SARC | Sarcoma | 247 | 2.4 | 0.6 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 23.2 | 24.4 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 19.5 | 12.5 | 20 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 1.2 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 0.6 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 7.3 | 8.1 | 0 |