Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | C553Y | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D189N | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D282H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | D507E | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I130V | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K703R | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | K750K | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L379P | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | N278I | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | P434S | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | R106T | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | S139C | Missense | 1 |
| BRCA | Breast invasive carcinoma | G208A | Missense | 1 |
| BRCA | Breast invasive carcinoma | L563L | Silent | 1 |
| BRCA | Breast invasive carcinoma | L650F | Missense | 1 |
| BRCA | Breast invasive carcinoma | S323N | Missense | 1 |
| BRCA | Breast invasive carcinoma | V29V | Silent | 1 |
| CESC | Cervical and endocervical cancers | H42D | Missense | 1 |
| COAD | Colon adenocarcinoma | A793A | Silent | 1 |
| COAD | Colon adenocarcinoma | G75D | Missense | 1 |
| COAD | Colon adenocarcinoma | K551N | Missense | 1 |
| COAD | Colon adenocarcinoma | R436L | Missense | 1 |
| COAD | Colon adenocarcinoma | R491H | Missense | 1 |
| COAD | Colon adenocarcinoma | R728W | Missense | 1 |
| COAD | Colon adenocarcinoma | Y791C | Missense | 1 |
| ESCA | Esophageal carcinoma | R700C | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | E212K | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | F622F | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | S759* | Nonsense | 1 |
| KIRC | Kidney renal clear cell carcinoma | N243Y | Missense | 1 |
| KIRC | Kidney renal clear cell carcinoma | N89H | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | L740P | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | P401T | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | Y528C | Missense | 1 |
| LUAD | Lung adenocarcinoma | G253V | Missense | 1 |
| LUAD | Lung adenocarcinoma | H568R | Missense | 1 |
| LUAD | Lung adenocarcinoma | M82I | Missense | 1 |
| LUAD | Lung adenocarcinoma | S223F | Missense | 1 |
| LUAD | Lung adenocarcinoma | S298C | Missense | 1 |
| LUAD | Lung adenocarcinoma | V240M | Missense | 1 |
| LUAD | Lung adenocarcinoma | Y115F | Missense | 1 |
| LUSC | Lung squamous cell carcinoma | L235L | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | A789V | Missense | 1 |
| PAAD | Pancreatic adenocarcinoma | Q358* | Nonsense | 1 |
| PAAD | Pancreatic adenocarcinoma | R436W | Missense | 1 |
| READ | Rectum adenocarcinoma | G161A | Missense | 1 |
| READ | Rectum adenocarcinoma | L717I | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G670E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | L92L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R747S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S30S | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | T91T | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | V329V | Silent | 1 |
| STAD | Stomach adenocarcinoma | G174G | Silent | 1 |
| STAD | Stomach adenocarcinoma | K718K | Silent | 1 |
| STAD | Stomach adenocarcinoma | L85L | Silent | 1 |
| STAD | Stomach adenocarcinoma | R634W | Missense | 1 |
| STAD | Stomach adenocarcinoma | R700C | Missense | 1 |
| THCA | Thyroid carcinoma | H618Y | Missense | 1 |
| THCA | Thyroid carcinoma | S796Y | Missense | 1 |
| THYM | Thymoma | G183D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A302S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | A793A | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | C592* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E195D | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E481G | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E766* | Nonsense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | K644K | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L100L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L357L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | L546L | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | N308S | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Q691Q | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S778S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T697A | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | Y90C | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 5 | 21.2 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 10 | 5.8 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 1.9 | 0 |
| COAD | Colon adenocarcinoma | 367 | 5 | 11.5 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 1.9 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 5 | 1.9 | 25 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 3.8 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 0 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 5.8 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 0 | 13.5 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 5 | 0 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 3.8 | 25 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 3.8 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 20 | 3.8 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 15 | 3.8 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 0 | 3.8 | 0 |
| THYM | Thymoma | 119 | 0 | 1.9 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 35 | 11.5 | 50 |