Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| PRAD | Prostate adenocarcinoma | G207G | Silent | 2 |
| PRAD | Prostate adenocarcinoma | Q212H | Missense | 2 |
| BLCA | Bladder urothelial carcinoma | D186H | Missense | 1 |
| BLCA | Bladder urothelial carcinoma | I305I | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | L283L | Silent | 1 |
| BLCA | Bladder urothelial carcinoma | Q212H | Missense | 1 |
| BRCA | Breast invasive carcinoma | D186N | Missense | 1 |
| BRCA | Breast invasive carcinoma | R635C | Missense | 1 |
| BRCA | Breast invasive carcinoma | R678G | Missense | 1 |
| BRCA | Breast invasive carcinoma | V197M | Missense | 1 |
| COAD | Colon adenocarcinoma | D123Y | Missense | 1 |
| COAD | Colon adenocarcinoma | E673* | Nonsense | 1 |
| COAD | Colon adenocarcinoma | L91L | Silent | 1 |
| COAD | Colon adenocarcinoma | Q212H | Missense | 1 |
| COAD | Colon adenocarcinoma | R144I | Missense | 1 |
| COAD | Colon adenocarcinoma | R660R | Silent | 1 |
| COAD | Colon adenocarcinoma | S28S | Silent | 1 |
| ESCA | Esophageal carcinoma | F176F | Silent | 1 |
| ESCA | Esophageal carcinoma | G207S | Missense | 1 |
| ESCA | Esophageal carcinoma | N109N | Silent | 1 |
| ESCA | Esophageal carcinoma | Q281L | Missense | 1 |
| GBM | Glioblastoma multiforme | G195G | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | A79A | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | C277C | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G204D | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | G292G | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | I305I | Silent | 1 |
| HNSC | Head and Neck squamous cell carcinoma | Q212H | Missense | 1 |
| KIRP | Kidney renal papillary cell carcinoma | Q217E | Missense | 1 |
| LGG | Brain Lower Grade Glioma | D53G | Missense | 1 |
| LGG | Brain Lower Grade Glioma | K132N | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | A321V | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | G222G | Silent | 1 |
| LUAD | Lung adenocarcinoma | G207G | Silent | 1 |
| LUAD | Lung adenocarcinoma | H183Y | Missense | 1 |
| LUAD | Lung adenocarcinoma | L86P | Missense | 1 |
| LUAD | Lung adenocarcinoma | N270T | Missense | 1 |
| LUAD | Lung adenocarcinoma | P169S | Missense | 1 |
| LUAD | Lung adenocarcinoma | Q217E | Missense | 1 |
| LUAD | Lung adenocarcinoma | R678R | Silent | 1 |
| LUSC | Lung squamous cell carcinoma | T617T | Silent | 1 |
| PAAD | Pancreatic adenocarcinoma | S253I | Missense | 1 |
| PRAD | Prostate adenocarcinoma | A172V | Missense | 1 |
| PRAD | Prostate adenocarcinoma | I305I | Silent | 1 |
| PRAD | Prostate adenocarcinoma | P317P | Silent | 1 |
| READ | Rectum adenocarcinoma | L329L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | F261F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | G110E | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | G207S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | P239P | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R645K | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | S278S | Silent | 1 |
| STAD | Stomach adenocarcinoma | G195G | Silent | 1 |
| STAD | Stomach adenocarcinoma | G206G | Silent | 1 |
| STAD | Stomach adenocarcinoma | G286G | Silent | 1 |
| STAD | Stomach adenocarcinoma | K650Q | Missense | 1 |
| STAD | Stomach adenocarcinoma | N625S | Missense | 1 |
| STAD | Stomach adenocarcinoma | P169P | Silent | 1 |
| STAD | Stomach adenocarcinoma | P622P | Silent | 1 |
| STAD | Stomach adenocarcinoma | P669T | Missense | 1 |
| STAD | Stomach adenocarcinoma | Q212H | Missense | 1 |
| STAD | Stomach adenocarcinoma | R115C | Missense | 1 |
| STAD | Stomach adenocarcinoma | R635H | Missense | 1 |
| TGCT | Testicular Germ Cell Tumors | C350F | Missense | 1 |
| THCA | Thyroid carcinoma | H647H | Silent | 1 |
| THCA | Thyroid carcinoma | P534S | Missense | 1 |
| THCA | Thyroid carcinoma | S94L | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | D24Y | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | S188S | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | V45A | Missense | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 6.5 | 5 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 0 | 10 | 0 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 0 | 0 |
| COAD | Colon adenocarcinoma | 367 | 9.7 | 7.5 | 100 |
| ESCA | Esophageal carcinoma | 185 | 6.5 | 5 | 0 |
| GBM | Glioblastoma multiforme | 283 | 3.2 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 12.9 | 5 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 2.5 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 5 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 3.2 | 2.5 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 6.5 | 12.5 | 0 |
| LUSC | Lung squamous cell carcinoma | 177 | 3.2 | 0 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 0 | 0 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 2.5 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 12.9 | 7.5 | 0 |
| READ | Rectum adenocarcinoma | 122 | 3.2 | 0 | 0 |
| SARC | Sarcoma | 247 | 0 | 0 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 9.7 | 7.5 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 16.1 | 15 | 0 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 2.5 | 0 |
| THCA | Thyroid carcinoma | 495 | 3.2 | 5 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 3.2 | 5 | 0 |