Silent
Missense
Nonsense
Frequency of SNVs in pancancer level
| Cancer | Full Name | Mutation | Mutation Type | Sample Number |
|---|---|---|---|---|
| BRCA | Breast invasive carcinoma | I431I | Silent | 1 |
| BRCA | Breast invasive carcinoma | L153V | Missense | 1 |
| BRCA | Breast invasive carcinoma | L49L | Silent | 1 |
| BRCA | Breast invasive carcinoma | S286* | Nonsense | 1 |
| CESC | Cervical and endocervical cancers | G24S | Missense | 1 |
| COAD | Colon adenocarcinoma | E134K | Missense | 1 |
| COAD | Colon adenocarcinoma | R327H | Missense | 1 |
| COAD | Colon adenocarcinoma | R9S | Missense | 1 |
| COAD | Colon adenocarcinoma | T96M | Missense | 1 |
| COAD | Colon adenocarcinoma | Y192Y | Silent | 1 |
| COAD | Colon adenocarcinoma | Y290H | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | K235N | Missense | 1 |
| HNSC | Head and Neck squamous cell carcinoma | M222I | Missense | 1 |
| LGG | Brain Lower Grade Glioma | A39T | Missense | 1 |
| LGG | Brain Lower Grade Glioma | L142M | Missense | 1 |
| LIHC | Liver hepatocellular carcinoma | I59F | Missense | 1 |
| LUAD | Lung adenocarcinoma | A163T | Missense | 1 |
| LUAD | Lung adenocarcinoma | A73A | Silent | 1 |
| LUAD | Lung adenocarcinoma | S286* | Nonsense | 1 |
| LUSC | Lung squamous cell carcinoma | R160L | Missense | 1 |
| OV | Ovarian serous cystadenocarcinoma | G74G | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | N267N | Silent | 1 |
| OV | Ovarian serous cystadenocarcinoma | V281G | Missense | 1 |
| READ | Rectum adenocarcinoma | P380S | Missense | 1 |
| SARC | Sarcoma | G386G | Silent | 1 |
| SARC | Sarcoma | G391S | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | F154F | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | H83Y | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | I59I | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | L113L | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | N82N | Silent | 1 |
| SKCM | Skin Cutaneous Melanoma | R121L | Missense | 1 |
| SKCM | Skin Cutaneous Melanoma | T361T | Silent | 1 |
| STAD | Stomach adenocarcinoma | C20C | Silent | 1 |
| STAD | Stomach adenocarcinoma | Q348* | Nonsense | 1 |
| STAD | Stomach adenocarcinoma | R160W | Missense | 1 |
| STAD | Stomach adenocarcinoma | S406P | Missense | 1 |
| STAD | Stomach adenocarcinoma | T340M | Missense | 1 |
| STAD | Stomach adenocarcinoma | T420R | Missense | 1 |
| STAD | Stomach adenocarcinoma | T96M | Missense | 1 |
| STAD | Stomach adenocarcinoma | V262V | Silent | 1 |
| THCA | Thyroid carcinoma | G214G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | E94K | Missense | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | G145G | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | R403R | Silent | 1 |
| UCEC | Uterine Corpus Endometrial Carcinoma | T373T | Silent | 1 |
Mutational percentage of Silent, Missense and Nonsense for various cancers
Summary of mutation in pancancer level
| Cancer | Full Name | # Sample | % Silent | % Missense | % Nonsense |
|---|---|---|---|---|---|
| BLCA | Bladder urothelial carcinoma | 394 | 0 | 0 | 0 |
| BRCA | Breast invasive carcinoma | 976 | 11.1 | 4 | 33.3 |
| CESC | Cervical and endocervical cancers | 194 | 0 | 4 | 0 |
| COAD | Colon adenocarcinoma | 367 | 5.6 | 20 | 0 |
| ESCA | Esophageal carcinoma | 185 | 0 | 0 | 0 |
| GBM | Glioblastoma multiforme | 283 | 0 | 0 | 0 |
| HNSC | Head and Neck squamous cell carcinoma | 511 | 0 | 8 | 0 |
| KIRC | Kidney renal clear cell carcinoma | 476 | 0 | 0 | 0 |
| KIRP | Kidney renal papillary cell carcinoma | 282 | 0 | 0 | 0 |
| LAML | Acute Myeloid Leukemia | 192 | 0 | 0 | 0 |
| LGG | Brain Lower Grade Glioma | 516 | 0 | 8 | 0 |
| LIHC | Liver hepatocellular carcinoma | 373 | 0 | 4 | 0 |
| LUAD | Lung adenocarcinoma | 533 | 5.6 | 4 | 33.3 |
| LUSC | Lung squamous cell carcinoma | 177 | 0 | 4 | 0 |
| OV | Ovarian serous cystadenocarcinoma | 465 | 11.1 | 4 | 0 |
| PAAD | Pancreatic adenocarcinoma | 126 | 0 | 0 | 0 |
| PCPG | Pheochromocytoma and Paraganglioma | 179 | 0 | 0 | 0 |
| PRAD | Prostate adenocarcinoma | 498 | 0 | 0 | 0 |
| READ | Rectum adenocarcinoma | 122 | 0 | 4 | 0 |
| SARC | Sarcoma | 247 | 5.6 | 4 | 0 |
| SKCM | Skin Cutaneous Melanoma | 290 | 27.8 | 8 | 0 |
| STAD | Stomach adenocarcinoma | 393 | 11.1 | 20 | 33.3 |
| TGCT | Testicular Germ Cell Tumors | 147 | 0 | 0 | 0 |
| THCA | Thyroid carcinoma | 495 | 5.6 | 0 | 0 |
| THYM | Thymoma | 119 | 0 | 0 | 0 |
| UCEC | Uterine Corpus Endometrial Carcinoma | 248 | 16.7 | 4 | 0 |